Interventions To Prevent Retinopathy of Prematurity: A Meta-analysis.

Abstract:

CONTEXT:The effectiveness of many interventions aimed at reducing the risk of retinopathy has not been well established. OBJECTIVE:To estimate the effectiveness of nutritional interventions, oxygen saturation targeting, blood transfusion management, and infection prevention on the incidence of retinopathy of prematurity (ROP). DATA SOURCES:A comprehensive search of several databases was conducted, including Medline, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus through March 2014. STUDY SELECTION:We included studies that evaluated nutritional interventions, management of supplemental oxygen, blood transfusions, or infection reduction and reported the incidence of ROP and mortality in neonates born at <32 weeks. DATA EXTRACTION:We extracted patient characteristics, interventions, and risk of bias indicators. Outcomes of interest were any stage ROP, severe ROP or ROP requiring treatment, and mortality. RESULTS:We identified 67 studies enrolling 21 819 infants. Lower oxygen saturation targets reduced the risk of developing any stage ROP (relative risk [RR] 0.86, 95% confidence interval [CI], 0.77-0.97) and severe ROP or ROP requiring intervention (RR 0.58, 95% CI, 0.45-0.74) but increased mortality (RR 1.15, 95% CI, 1.04-1.29). Aggressive parenteral nutrition reduced the risk of any stage ROP but not severe ROP. Supplementation of vitamin A, E, or inositol and breast milk feeding were beneficial but only in observational studies. Use of transfusion guidelines, erythropoietin, and antifungal agents were not beneficial. LIMITATIONS:Results of observational studies were not replicated in randomized trials. Interventions were heterogeneous across studies. CONCLUSIONS:At the present time, there are no safe interventions supported with high quality evidence to prevent severe ROP.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Fang JL,Sorita A,Carey WA,Colby CE,Murad MH,Alahdab F

doi

10.1542/peds.2015-3387

subject

Has Abstract

pub_date

2016-04-01 00:00:00

issue

4

eissn

0031-4005

issn

1098-4275

pii

peds.2015-3387

journal_volume

137

pub_type

杂志文章,meta分析,评审
  • Marijuana and Tobacco Coexposure in Hospitalized Children.

    abstract:BACKGROUND:The impact of secondhand marijuana smoke exposure on children is unknown. New methods allow for the detection of marijuana smoke exposure in children. METHODS:We studied children who were hospitalized in Colorado and had a parent participating in a smoking cessation study; all children had urine samples rem...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2018-0820

    authors: Wilson KM,Torok MR,Wei B,Wang L,Lowary M,Blount BC

    更新日期:2018-12-01 00:00:00

  • Circulating pro- and counterinflammatory cytokine levels and severity in necrotizing enterocolitis.

    abstract:OBJECTIVES:To evaluate the relationship between the severity of necrotizing enterocolitis (NEC) and circulating concentrations of proinflammatory cytokines interleukin (IL)-1beta and IL-8 and counterinflammatory cytokines IL-1 receptor antagonist (IL-1ra) and IL-10. These cytokines have been associated with bowel injur...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.103.4.766

    authors: Edelson MB,Bagwell CE,Rozycki HJ

    更新日期:1999-04-01 00:00:00

  • Developmental changes in energy expenditure and physical activity in children: evidence for a decline in physical activity in girls before puberty.

    abstract:OBJECTIVE:To examine individual changes in energy expenditure and physical activity during prepubertal growth in boys and girls. METHODS:Total energy expenditure (TEE), resting energy expenditure, physical activity-related energy expenditure, reported physical activity, and fat and fat-free mass were measured three ti...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.101.5.887

    authors: Goran MI,Gower BA,Nagy TR,Johnson RK

    更新日期:1998-05-01 00:00:00

  • Self-reported quality of life of young children with conditions from early infancy: a systematic review.

    abstract:CONTEXT:There is little consistency in the use of instruments for measuring self-reported quality of life (QoL) in young children. OBJECTIVE:To systematically review studies of self-reported QoL in children aged <12 years with congenital health conditions, and to examine the agreement between self- and proxy-reports. ...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2014-0352

    authors: Jardine J,Glinianaia SV,McConachie H,Embleton ND,Rankin J

    更新日期:2014-10-01 00:00:00

  • Dietary fiber in weaning foods of young children.

    abstract:OBJECTIVE:An evaluation of the opportunity to introduce fiber in the diet of weaning infants. METHODS:A descriptive review of the literature to assess the role of fiber in the following dietary interventions: (1) definition of the nutrient amounts that meet the weaning infant's physiologic needs; (2) modulation of dig...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Agostoni C,Riva E,Giovannini M

    更新日期:1995-11-01 00:00:00

  • Cerebral oxygenation in preterm infants.

    abstract:BACKGROUND AND OBJECTIVE:Prone sleeping is a major risk factor for sudden infant death syndrome (SIDS) and preterm infants are at significantly increased risk. In term infants, prone sleeping is associated with reduced mean arterial pressure (MAP) and cerebral tissue oxygenation index (TOI). However, little is known ab...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2014-0773

    authors: Fyfe KL,Yiallourou SR,Wong FY,Odoi A,Walker AM,Horne RS

    更新日期:2014-09-01 00:00:00

  • United States vaccine research: a delicate fabric of public and private collaboration. National Vaccine Advisory Committee.

    abstract::In the last 20 years, two thirds of all new vaccines provided worldwide have been produced by a US network of independent industrial, governmental, and academic partners engaged in vaccine research and development. Vaccines are complex products and the science of vaccinology is difficult. To achieve the full promise o...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.100.6.1015

    authors:

    更新日期:1997-12-01 00:00:00

  • "You are hereby commanded to appear": pediatrician subpoena and court appearance in child maltreatment.

    abstract:OBJECTIVE:To determine the frequency of court appearance by pediatricians evaluating child abuse and neglect cases and to identify case characteristics associated with actual court appearance or case adjournment. DESIGN:Retrospective review of subpoenas received between 1995 and 1999 for child maltreatment cases perso...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.107.6.1427

    authors: Palusci VJ,Hicks RA,Vandervort FE

    更新日期:2001-06-01 00:00:00

  • Pediatric Psychopharmacology for Treatment of ADHD, Depression, and Anxiety.

    abstract::The pediatric practitioner is often the first point-of-contact for children and adolescents suffering from mental illness. Part of the treatment planning for psychiatric diagnoses includes consideration of medication. Attention-deficit/hyperactivity disorder, one of the most common diagnoses, is very responsive to sti...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2014-1581

    authors: Southammakosane C,Schmitz K

    更新日期:2015-08-01 00:00:00

  • Prevention and management of positional skull deformities in infants. American Academy of Pediatrics Committee on Practice and Ambulatory Medicine, Section on Plastic Surgery and Section on Neurological Surgery.

    abstract::Cranial asymmetry may be present at birth or may develop during the first few months of life. Over the past several years, pediatricians have seen an increase in the number of children with cranial asymmetry, particularly unilateral flattening of the occiput. This increase likely is attributable to parents following t...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章,实务指引

    doi:10.1542/peds.112.1.199

    authors: Persing J,James H,Swanson J,Kattwinkel J,American Academy of Pediatrics Committee on Practice and Ambulatory Medicine, Section on Plastic Surgery and Section on Neurological Surgery.

    更新日期:2003-07-01 00:00:00

  • Treatment of chronic childhood asthma with beclomethasone dipropionate aerosols: II. Effect on pituitary-adrenal function after substitution for oral corticosteroids.

    abstract::The effects of beclomethasone, dipropionate aerosol (DBA) (400 microgram/day) on clinical course, pulmonary function, and pituitary-adrenal function was studied in 34 steroid-dependent asthmatic children. Asthma severity was assessed by daily symptom and medication scores, peak flow measured three times a day, and wee...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:

    authors: Kershnar H,Klein R,Waldman D,Berger W,Rachelefsky G,Katz R,Siegel S

    更新日期:1978-08-01 00:00:00

  • Incidence, prognosis, and risk factors for fatigue and chronic fatigue syndrome in adolescents: a prospective community study.

    abstract:OBJECTIVE:The objective of this study was to describe the incidence, prevalence, risk factors, and prognosis of fatigue, chronic fatigue, and chronic fatigue syndrome in 11- to 15-year-olds. METHODS:A random general population sample (n = 842) of British adolescents and their parents were assessed at baseline and 4 to...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-2231

    authors: Rimes KA,Goodman R,Hotopf M,Wessely S,Meltzer H,Chalder T

    更新日期:2007-03-01 00:00:00

  • Nutritional practices in the neonatal intensive care unit: analysis of a 2006 neonatal nutrition survey.

    abstract:OBJECTIVE:The goal of this investigation was to determine how current parenteral nutrition and enteral nutrition practice intentions for preterm infants compare with published recommendations and previous feeding practices. METHODS:A survey of feeding strategies for 3 preterm infant weight groups was sent to NICU dire...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-3644

    authors: Hans DM,Pylipow M,Long JD,Thureen PJ,Georgieff MK

    更新日期:2009-01-01 00:00:00

  • Expanding the availability of extracorporeal cardiopulmonary resuscitation.

    abstract::A healthy 14-year-old presented to an emergency department in Alaska, complaining of shortness of breath, chest pain, and 72 hours of malaise and headache. On admission, her blood pressure was 80/50 mm Hg, and she had cool extremities. Electrocardiography revealed wide-complex ventricular tachycardia. She underwent sy...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-2371

    authors: McMullan DM

    更新日期:2013-03-01 00:00:00

  • Ethical Implications for Providers Regarding Cannabis Use in Children With Autism Spectrum Disorders.

    abstract::Children with autism spectrum disorder (ASD) are at risk for self-injurious behaviors that can be difficult to treat in the context of co-occurring low IQ and adaptive skills. Increased prevalence and decriminalization of cannabis in some states have led to more frequent questions for pediatricians about the use of ca...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2018-0558

    authors: Duvall SW,Lindly O,Zuckerman K,Msall ME,Weddle M

    更新日期:2019-02-01 00:00:00

  • The Seattle children's bicycle helmet campaign: changes in helmet use and head injury admissions.

    abstract:OBJECTIVE:To describe the impact of a community bicycle helmet campaign on helmet use and the incidence of bicycle-related head injuries. SETTING:Metropolitan community and a large health maintenance organization. INTERVENTIONS:Communitywide bicycle helmet campaign. OUTCOMES:Rate of observed bicycle helmet use in th...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Rivara FP,Thompson DC,Thompson RS,Rogers LW,Alexander B,Felix D,Bergman AB

    更新日期:1994-04-01 00:00:00

  • Parent diet modification, child activity, or both in obese children: an RCT.

    abstract:OBJECTIVES:Outcomes of childhood obesity interventions are rarely reported beyond 1 year. We hypothesized that the impact on the BMI z score from a child-centered physical-activity program in combination with a parent-centered dietary-modification program would be greater than either program conducted alone at 24 month...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2010-1518

    authors: Collins CE,Okely AD,Morgan PJ,Jones RA,Burrows TL,Cliff DP,Colyvas K,Warren JM,Steele JR,Baur LA

    更新日期:2011-04-01 00:00:00

  • Free Tax Services in Pediatric Clinics.

    abstract:OBJECTIVES:The earned income tax credit (EITC), refundable monies for America's working poor, is associated with improved child health. Yet, 20% of eligible families do not receive it. We provided free tax preparation services in clinics serving low-income families and assessed use, financial impact, and accuracy. MET...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-3608

    authors: Marcil LE,Hole MK,Wenren LM,Schuler MS,Zuckerman BS,Vinci RJ

    更新日期:2018-06-01 00:00:00

  • Developmental care does not alter sleep and development of premature infants.

    abstract:OBJECTIVE:The Neonatal Individualized Developmental Care Program (NIDCAP) for very low birth weight (VLBW) preterm infants has been suggested by Als et al to improve several medical outcome variables such as time on ventilator, time to nipple feed, the duration of hospital stay, better behavioral performance on Assessm...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1542/peds.100.6.e9

    authors: Ariagno RL,Thoman EB,Boeddiker MA,Kugener B,Constantinou JC,Mirmiran M,Baldwin RB

    更新日期:1997-12-01 00:00:00

  • Treatment outcomes of overweight children and parents in the medical home.

    abstract:OBJECTIVE:To test in the primary care setting the short- and long-term efficacy of a behavioral intervention that simultaneously targeted an overweight child and parent versus an information control (IC) targeting weight control only in the child. METHODS:Two- to 5-year-old children who had BMI ≥85th percentile and an...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2013-4084

    authors: Quattrin T,Roemmich JN,Paluch R,Yu J,Epstein LH,Ecker MA

    更新日期:2014-08-01 00:00:00

  • Microstream capnography improves patient monitoring during moderate sedation: a randomized, controlled trial.

    abstract:BACKGROUND:Investigative efforts to improve monitoring during sedation for patients of all ages are part of a national agenda for patient safety. According to the Institute of Medicine, recent technological advances in patient monitoring have contributed to substantially decreased mortality for people receiving general...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2005-1709

    authors: Lightdale JR,Goldmann DA,Feldman HA,Newburg AR,DiNardo JA,Fox VL

    更新日期:2006-06-01 00:00:00

  • Improving transition from pediatric to adult cystic fibrosis care: lessons from a national survey of current practices.

    abstract:OBJECTIVES:More than 500,000 adolescents with special health care needs age into adulthood each year in the United States, and there is growing recognition of the need for support of their transition to adult-oriented health care. Because of improved survival, cystic fibrosis has experienced this increasing transition ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-2217

    authors: McLaughlin SE,Diener-West M,Indurkhya A,Rubin H,Heckmann R,Boyle MP

    更新日期:2008-05-01 00:00:00

  • Effect of honey on nocturnal cough and sleep quality: a double-blind, randomized, placebo-controlled study.

    abstract:OBJECTIVES:To compare the effects of a single nocturnal dose of 3 honey products (eucalyptus honey, citrus honey, or labiatae honey) to placebo (silan date extract) on nocturnal cough and difficulty sleeping associated with childhood upper respiratory tract infections (URIs). METHODS:A survey was administered to paren...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2011-3075

    authors: Cohen HA,Rozen J,Kristal H,Laks Y,Berkovitch M,Uziel Y,Kozer E,Pomeranz A,Efrat H

    更新日期:2012-09-01 00:00:00

  • National patterns of aspirin use and Reye syndrome reporting, United States, 1980 to 1985.

    abstract::The number of cases of Reye syndrome reported annually to the Centers for Disease Control declined markedly between 1980 and 1985. In this article, we present pharmaceutical marketing research data that suggest sharp decreases in the use and purchase of children's aspirin between 1980 and 1985. These trends appear to ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Arrowsmith JB,Kennedy DL,Kuritsky JN,Faich GA

    更新日期:1987-06-01 00:00:00

  • Dating violence and associated sexual risk and pregnancy among adolescent girls in the United States.

    abstract:OBJECTIVES:To assess the annual prevalence of physical violence from dating partners among a representative sample of sexually experienced adolescent girls attending US public and private high schools, as well as sexual risk behaviors and pregnancy among this population. DESIGN, SETTING, PARTICIPANTS, AND MEASURES:Fem...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.114.2.e220

    authors: Silverman JG,Raj A,Clements K

    更新日期:2004-08-01 00:00:00

  • Multiple organ failure after ingestion of pennyroyal oil from herbal tea in two infants.

    abstract:BACKGROUND:Hepatic and neurologic injury developed in two infants after ingestion of mint tea. Examination of the mint plants, from which the teas were brewed, indicated that they contained the toxic agent pennyroyal oil. METHODS:Sera from each infant were analyzed for the toxic constituents of pennyroyal oil, includi...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Bakerink JA,Gospe SM Jr,Dimand RJ,Eldridge MW

    更新日期:1996-11-01 00:00:00

  • Relative impact of influenza and respiratory syncytial virus in young children.

    abstract:OBJECTIVE:We measured the relative impact of influenza and respiratory syncytial virus (RSV) infections in young children in terms of emergency department (ED) visits, clinical care requirements, and overall resource use. METHODS:Patients who were aged

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-3074

    authors: Bourgeois FT,Valim C,McAdam AJ,Mandl KD

    更新日期:2009-12-01 00:00:00

  • Metopic craniostenosis as a consequence of fetal head constraint: two interesting experiments of nature.

    abstract::Two instances of metopic craniosynostosis provide dramatic experiments of nature which implicate fetal head constraint as one cause of early sutural fusion. The presumed restriction of growth stretch at the metopic suture in one instance was due to a bicornuate uterus in which the fetal head was markedly constrained. ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Graham JM Jr,Smith DW

    更新日期:1980-05-01 00:00:00

  • Reducing violent injuries: priorities for pediatrician advocacy.

    abstract::A basic framework for developing an advocacy plan must systematically break down the large task of policy development implementation into manageable components. The basic framework described in detail in this paper includes three steps: Setting policy objectives by narrowing the scope of policy, by reviewing policy op...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Dolins JC,Christoffel KK

    更新日期:1994-10-01 00:00:00

  • Disseminated fungal infections in very low-birth-weight infants: therapeutic toxicity.

    abstract::The improved survival of very low-birth-weight infants, who require prolonged hospitalization and many invasive procedures, increases the risks for nosocomial illnesses, such as disseminated fungal infections. In a 2-year period, systemic fungal infections were clinically diagnosed in ten infants. This necessitated th...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Baley JE,Kliegman RM,Fanaroff AA

    更新日期:1984-02-01 00:00:00