Combination antifungals as an effective means of salvage in paediatric leukaemia patients with invasive fungal infections.

Abstract:

:Invasive fungal infections (IFIs) are an important cause of morbidity and mortality in paediatric leukaemias. Antifungal combinations to treat these patients are being explored. Fourteen children with leukaemias and IFIs were treated with a combination of antifungal agents at our centre. The first antifungal was amphotericin-B in 13 children and voriconazole in one child. In view of no improvement and clinical deterioration, in nine patients, voriconazole was added as the second antifungal agent and in four, it was caspofungin. All patients completed 4-6 weeks of antifungal therapy. The overall mortality attributable to IFI for the cohort was 4/14 (28%).

journal_name

Indian J Med Microbiol

authors

Meena JP,Gupta AK,Jana M,Seth R

doi

10.4103/ijmm.IJMM_18_157

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

109-112

issue

1

eissn

0255-0857

issn

1998-3646

pii

IndianJMedMicrobiol_2019_37_1_109_264475

journal_volume

37

pub_type

杂志文章
  • Necrotizing (malignant) otitis externa: an unusual localization of mucormycosis.

    abstract::Malignant otitis externa (MOE) is a severe infection of external auditory canal and skull base. A 17-year-old diabetic girl was admitted with diabetic ketoacidosis. Cellulitis of her right ear occurred on the second day of hospitalization and a black necrotic scar in the same region appeared on the next day. The lesio...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.29390

    authors: Tuzcu A,Bahceci M,Celen MK,Kilinc N,Ozmen S

    更新日期:2006-10-01 00:00:00

  • Cutaneous cryptococcosis among HIV infected patients.

    abstract::Five patients with HIV associated cutaneous cryptococcal infection are reported. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Vasanthi S,Padmavathy BK,Gopal R,Sundaram RS,Manoharan G

    更新日期:2002-07-01 00:00:00

  • A pilot study of Chlamydia trachomatis pneumonia in infants.

    abstract::Chlamydia trachomatis is currently recognized as one of the most common sexually transmitted pathogen and a major cause of perinatally acquired infection. Vertical transmission of infection from mother to the infant may result in the development of conjunctivitis and pneumonia. The study was conducted with the aim of ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Chawla R,Bhalla P,Sachdev HP

    更新日期:2004-07-01 00:00:00

  • Rising trend of antimicrobial resistance among Neisseria gonorrhoeae isolates and the emergence of N. gonorrhoeae isolate with decreased susceptibility to ceftriaxone.

    abstract:CONTEXT:Gonorrhoea is one of the most common sexually transmitted infections (STI) in developing countries and is a global health problem. AIMS:To analyze the trend of antimicrobial susceptibility of Neisseria gonorrhoeae isolates over the years, in a tertiary care hospital of North India. SETTINGS AND DESIGN:The stu...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.148374

    authors: Bharara T,Bhalla P,Rawat D,Garg VK,Sardana K,Chakravarti A

    更新日期:2015-01-01 00:00:00

  • Blood culture gram stain, acridine orange stain and direct sensitivity-based antimicrobial therapy of bloodstream infection in patients with trauma.

    abstract:PURPOSE:The purpose of this study was to ascertain if the simple practice of Gram stain, acridine orange stain and direct sensitivity determination of positive blood culture bottles could be used to guide early and appropriate treatment in trauma patients with clinical suspicion of sepsis. The study also aimed to evalu...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.62491

    authors: Behera B,Mathur P,Gupta B

    更新日期:2010-04-01 00:00:00

  • Types of human papillomavirus observed in hospital-based population.

    abstract:Background and Objectives:Human papillomavirus (HPV) is the causative agent of cervical cancer, a major cause of cancer mortality in Indian women. The current study was undertaken to add information to the existing data on HPV type distribution in Indians, in an attempt to document HPV types for future vaccination prog...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_19_451

    authors: Wagh P,Kulkarni P,Kerkar S,Tongaonkar H,Deodhar K,Rekhi B,Salvi V,Chaudhari H,Warke H,Mania-Pramanik J

    更新日期:2019-10-01 00:00:00

  • Unimicrobial appendicitis due to non-vaccine serotype of streptococcus pneumoniae: Implications for and management and prevention.

    abstract::The aetiology of appendicitis is usually polymicrobial. We report a rare case of appendicitis caused by Streptococcus pneumoniae as the only causative organism. The case assumes significance because it occurs in the absence of any predisposing factor for invasive pneumococcal infection, it is unimicrobial, it may lead...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Bhattacharya S,Kanungo R,Natarajan MK,Mahalakshmi VN,Srinivasan K

    更新日期:2001-04-01 00:00:00

  • Recent advances in rhinosporidiosis and Rhinosporidium seeberi.

    abstract::Rhinosporidiosis and its causative pathogen Rhinosporidium seeberi have been known for over a hundred years. Yet unresolved enigmas in rhinosporidiosis include the mode of infection, mechanisms of spread, mechanisms of immunity, some aspects of histopathology e.g. the significance of transepidermal elimination of spor...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Arseculeratne SN

    更新日期:2002-07-01 00:00:00

  • The presence of dsRNA virus in Trichomonas vaginalis isolates from symptomatic and asymptomatic Indian women and its correlation with in vitro metronidazole sensitivity.

    abstract:PURPOSE:Trichomonas vaginalis, a protozoan parasite, is the causative agent of human trichomoniasis, the most common non-viral sexually transmitted disease. The infection encompasses from a complete asymptomatic presentation to severe sequelae; yet, the virulence markers have been poorly understood. It is suggested tha...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.81801

    authors: Malla N,Kaul P,Sehgal R,Gupta I

    更新日期:2011-04-01 00:00:00

  • Extended spectrum beta lactamase (ESBL) mediated resistance to third generation cephalosporins among Klebsiella pneumoniae in Chennai.

    abstract:PURPOSE:To examine the incidence of extended spectrum b lactamase (ESbL) producing strains and multidrug resistant strains of Klebsiella pneumoniae isolated from children between 0-5 years of age. METHODS:Multidrug resistance and ESbL production was studied in a total of 120 isolates of Klebsiella pneumoniae obtained ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Subha A,Ananthan S

    更新日期:2002-04-01 00:00:00

  • Dynamics of the occurrence of influenza in relation to seasonal variation in Chennai, Tamil Nadu: A 7 -year cumulative study.

    abstract:Background:Influenza viruses have emerged as virulent pathogens causing considerable burden across the world. A thorough understanding of the pattern in occurrence of influenza globally is the need of hour. The present study deals with analysis of the dynamics of Influenza virus, especially the influence of seasonal ch...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_19_226

    authors: Kiruba R,Suresh Babu BV,Sheriff AK,Gunasekaran P,Anupama CP,Saran N,Kumar VS,Padmapriya P,Chakravarthy NN,Kaveri K

    更新日期:2019-07-01 00:00:00

  • Corynebacterium striatum: an emerging nosocomial pathogen in a case of laryngeal carcinoma.

    abstract::Corynebacterium striatum is an emerging nosocomial pathogen associated with wound infections, pneumonia and meningitis. It is also a multidrug-resistant pathogen causing high morbidity. This is a report of an unusual case of wound infection in a patient with laryngeal carcinoma. Accurate diagnosis of the infection and...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.136589

    authors: Biswal I,Mohapatra S,Deb M,Dawar R,Gaind R

    更新日期:2014-07-01 00:00:00

  • Disseminated cryptococcosis in a patient with nephrotic syndrome.

    abstract::Disseminated cryptococcosis mainly occurs in patients with impaired cell mediated immunity. We present a case of disseminated cryptococcosis in a non-HIV patient with nephrotic syndrome who never received immunosuppression. Cultures of bone marrow aspirate, cerebrospinal fluid analysis and histology of skin lesions we...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.25209

    authors: Qadir F,Manzoor K,Ahmed E

    更新日期:2006-04-01 00:00:00

  • Ophthalmomyiasis: three cases from North India.

    abstract::Three cases of external ophthalmomyiasis are reported here. The larvae were identified to be Oestrus ovis in two cases and Cochliomyia hominivorax in one. Two of the patients were immunocompetent while one was undergoing treatment for squamous cell carcinoma of eyelid. In the latter myiasis led to complete destruction...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.66490

    authors: Khurana S,Biswal M,Bhatti HS,Pandav SS,Gupta A,Chatterjee SS,Lyngdoh WV,Malla N

    更新日期:2010-07-01 00:00:00

  • Erratum: Endemic Indian clones of Klebsiella pneumoniae harbouring New Delhi metallo beta lactamase 1 on a hybrid plasmid replicon type: A case of changing New Delhi metallo beta lactamase plasmid landscapes in India?

    abstract::[This corrects the article DOI: 10.4103/0255-0857.188314.]. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 已发布勘误

    doi:10.4103/0255-0857.195384

    authors:

    更新日期:2016-10-01 00:00:00

  • Identification of Raoultella spp.: Comparison of three methods.

    abstract:Background:Raoultella is a Gram-negative bacteria, which commonly occur in the natural environment such as water, soil and on plants. In recent years, Raoultella spp. gained more interest. There is also an increasing number of publications describing mainly clinical cases involving these bacteria. Identification of Rao...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_17_99

    authors: Sekowska A,Mikucka A,Gospodarek-Komkowska E

    更新日期:2018-04-01 00:00:00

  • Human subcutaneous dirofilariasis in India: a report of three cases with brief review of literature.

    abstract::Human subcutaneous dirofilariasis is a rare infection caused by filarial worms of the genus Dirofilaria. The parasites are transmitted to man by mosquitoes and the infection is manifested as subcutaneous nodules. Excision of the lesion is both diagnostic and therapeutic. Hereby we report three cases of human subcutane...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章,评审

    doi:10.4103/0255-0857.71836

    authors: Khurana S,Singh G,Bhatti HS,Malla N

    更新日期:2010-10-01 00:00:00

  • Molecular characterisation and clinical correlates of rotavirus in children and adults in a tertiary care centre, Chennai, South India.

    abstract:AIMS:This study was undertaken to determine the rate of detection of rotavirus causing diarrhoea among children and adults, identify the common genotypes circulating and determine clinical correlates. SETTINGS AND DESIGN:This is a cross-sectional study in a tertiary care centre. MATERIALS AND METHODS:Stool samples we...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_16_51

    authors: Selvarajan S,Reju S,Pushpanathan P,Arumugam R,Padmanabhan R,Kothandaramanujam SM,Srikanth P,Kang G

    更新日期:2017-04-01 00:00:00

  • Trichosporon asahii as an emerging etiologic agent of disseminated trichosporonosis: a case report and an update.

    abstract:PURPOSE:To report a fatal case of disseminated trichosporonosis caused by Trichosporon asahii in a patient with acute myeloblastic leukemia (AML) and to present an update on systemic trichosporonosis with special reference to India. METHODS:The diagnosis was based on repeated demonstration of budding yeast cells and a...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Chowdhary A,Ahmad S,Khan ZU,Doval DC,Randhawa HS

    更新日期:2004-01-01 00:00:00

  • Identification of opportunistic enteric parasites among immunocompetent patients with diarrhoea from Northern India and genetic characterisation of Cryptosporidium and Microsporidia.

    abstract:PURPOSE:Enteric parasitic infestation is a major public health problem in developing countries. Parasites such as Cryptosporidium spp., Cyclospora spp., Cystoisospora spp. and Microsporidia may cause severe diarrhoea among immunocompromised patients. There is scanty data on their frequency among immunocompetent patient...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.174114

    authors: Ghoshal U,Dey A,Ranjan P,Khanduja S,Agarwal V,Ghoshal UC

    更新日期:2016-01-01 00:00:00

  • In vitro analysis of the minimal inhibitory concentration values of different generations of anti-methicillin-resistant Staphylococcus aureus antibiotics.

    abstract::Methicillin-resistant Staphylococcus aureus (MRSA) resistance to antimicrobials may result in the increased risk of treatment failure. The objective of the study was to analyse in vitro MRSA susceptibility to vancomycin, linezolid, daptomycin, tigecycline, ceftaroline, dalbavancin, clindamycin, ciprofloxacin and trime...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_17_136

    authors: Guzek A,Rybicki Z,Tomaszewski D

    更新日期:2018-01-01 00:00:00

  • The seroepidemiology of Rubella in Amritsar (Punjab).

    abstract::Seroprevalence of Rubella was determined in 580 women including 80 women of medical community of district Amritsar, by ELISA test. The overall Rubella IgG seropositivity was 68.8% while in women of medical community it was 80%. Maximum number of women were seropositive (77.2%) in age group 26-35 years. Significantly h...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Singla N,Jindal N,Aggarwal A

    更新日期:2004-01-01 00:00:00

  • Ludwig's angina by Salmonella Typhi: a clinical dilemma.

    abstract::Salmonella Typhi has rarely been associated with focal abscesses; and in literature, there is no evidence of its association with abscesses in the neck spaces. Ability of Salmonella Typhi to invade and localise in the neck spaces not only poses a diagnostic challenge but also underscores the necessity to understand th...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.154889

    authors: Mahajan RK,Sharma S,Madan P,Sharma N

    更新日期:2015-04-01 00:00:00

  • Prevalence and antimicrobial resistance pattern of multidrug-resistant enterococci isolated from clinical specimens.

    abstract:PURPOSE:Vancomycin-resistant enterococci (VRE) pose an emerging problem in hospitals worldwide. The present study was undertaken to determine the occurrence, species prevalence, antibacterial resistance, and phenotypic and genetic characteristics of VRE isolated in Riyadh hospitals, KSA. MATERIALS AND METHODS:Two hund...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.93032

    authors: Salem-Bekhit MM,Moussa IM,Muharram MM,Alanazy FK,Hefni HM

    更新日期:2012-01-01 00:00:00

  • Bacteremia due to Rhodococcus equi in an immunocompetent infant.

    abstract::Rhodococcus equi , previously known as Corynebacterium equi, is one of the most important causes of zoonotic infection in grazing animals. Increased cases of human infection with R. equi have been reported especially in immunocompromised patients. Infection in immunocompetent patients is extremely rare. We report a ca...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.76529

    authors: Devi P,Malhotra S,Chadha A

    更新日期:2011-01-01 00:00:00

  • A rare case of tubercular cerebellar abscess.

    abstract::Tubercular brain abscess are uncommon and tubercular cerebellar abscess are rarely reported. Most of these cases occur in immunocompromised patients. We report a case of multiple cerebellar abscesses in a 55-year-old HIV seronegative non-diabetic female, who complained of headache, neck pain and unsteadiness of gait s...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.55464

    authors: Wanjari K,Baradkar VP,Nataraj G,Kumar S

    更新日期:2009-10-01 00:00:00

  • Increased prevalence of extended spectrum beta lactamase producers in neonatal septicaemic cases at a tertiary referral hospital.

    abstract::Emergence of extended spectrum beta lactamases (ESBLs) producing strains of gram negative bacteria, as one of the leading cause of septicaemia often complicates the clinical and therapeutic outcome. The present study was undertaken to investigate the prevalence of ESBLs in bacteria isolated from neonatal septicaemic c...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.43578

    authors: Bhattacharjee A,Sen MR,Prakash P,Gaur A,Anupurba S

    更新日期:2008-10-01 00:00:00

  • Eumycetoma pedis due to Exophiala jeanselmei.

    abstract::A case of eumycetoma of foot in an 8-year old male child was clinically diagnosed as chronic osteomyelitis and was microbiologically confirmed as eumycetoma. The case is being reported for its uncommon clinical presentation and etiological agent, Exophiala jeanselmei. The patient recovered completely after treatment w...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.32726

    authors: Capoor MR,Khanna G,Nair D,Hasan A,Rajni,Deb M,Aggarwal P

    更新日期:2007-04-01 00:00:00

  • Pre-transplant cytomegalovirus immunoglobulin G antibody levels could prevent severe cytomegalovirus infections post-transplant in liver transplant recipients: Experience from a tertiary care liver centre.

    abstract:BACKGROUND:Humoral immune responses in cytomegalovirus (CMV) are not studied well. Pre-transplant CMV immunoglobulin G (IgG) antibody levels (Pre-Tx IgG) could influence the occurrence of post-transplant CMV infections. OBJECTIVE:Correlation between pre-Tx IgG and post-Tx risk of acquiring CMV infection was investigat...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_17_201

    authors: Gupta E,Pamecha V,Verma Y,Kumar N,Rastogi A,Hasnian N,Bhadoria AS

    更新日期:2017-10-01 00:00:00

  • Assessment of microbiological status after successful completion of intermittent revised national tuberculosis control programme directly observed treatment, short course regimen for microbiologically confirmed pulmonary tuberculosis cases: While new dail

    abstract:Purpose:The Revised National Tuberculosis Control Programme (RNTCP) is now introducing daily fixed-dose regimen instead of Directly Observed Treatment, Short Course (DOTS) regimen for treatment of drug-sensitive tuberculosis (TB) in India. It would be beneficial to understand the drawbacks, barriers and advantages of t...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_18_65

    authors: Ghosh R,Roy S,Rashid MK

    更新日期:2018-04-01 00:00:00