Abstract:
INTRODUCTION:Platelet-rich plasma (PRP) is a blood component therapy with a supraphysiological concentration of platelets derived from allogenic or, more commonly, autologous blood. PRP has been used in different non-transfusion indications because of its role in the promotion of tissue repair and healing, in fields such as Traumatology, Dermatology and Dentistry. OBJECTIVE:To provide a synthesis of the efficacy of PRP for different clinical situations. METHODS:Systematic searches were carried out in MEDLINE, Embase, Cochrane Library and LILACS in July 2018 to identify systematic reviews (SRs) of randomized clinical trials (RCTs) focusing on PRP for non-transfusion use. Two authors independently screened all retrieved references in two stages (titles and abstracts at a first stage and full texts at a second stage). The methodological quality of SRs that met the eligibility criteria was appraised by AMSTAR 2. Conclusions were based on the most recent SRs with highest quality. RESULTS:One thousand two hundred and forty references were retrieved. After checking the inclusion criteria, 29 SRs of RCTs related to three different fields (wound care, Orthopedics and Dentistry) were included. The results suggest the benefit of PRP for different clinical situations, such as diabetic wounds, acute lesions of musculoskeletal system, rotator cuff lesions, tendinopathies, knee and hip osteoarthritis, total knee arthroplasty, allogenic bone graft for dental implants and periodontal intrabony defects. CONCLUSION:There is low to moderate quality evidence supporting the efficacy of PRP for specific clinical situations. The low quality of the evidence limits the certainty of these findings. Well-planned and well-conducted RCTs are still needed to further assess the efficacy of PRP.
journal_name
Int J Clin Practjournal_title
International journal of clinical practiceauthors
Pachito DV,Latorraca COC,Riera Rdoi
10.1111/ijcp.13402subject
Has Abstractpub_date
2019-11-01 00:00:00pages
e13402issue
11eissn
1368-5031issn
1742-1241journal_volume
73pub_type
杂志文章abstract:BACKGROUND:Although many models have been developed to explain health behaviour, differences in individual response to symptoms remain largely unexplained; moreover, they tend to underestimate affective (i.e., emotional) processes and they neglect the construct of well-being, despite its predominant role in the definit...
journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2009.02183.x
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abstract::A prospective survey of patients attending day case surgery was undertaken to determine patient satisfaction. In an eight-week prospective study, patients undergoing procedures in the day surgical unit were asked to fill in two questionnaires, the first before surgery and the second two weeks after surgery. One hundre...
journal_title:International journal of clinical practice
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abstract::Men with cardiovascular disease (CVD) are more likely to have erectile dysfunction (ED) than the general population, as both conditions share risk factors and some drugs used to treat CVD may induce ED as a side-effect. This study was undertaken to assess the efficacy and safety of sildenafil citrate for the treatment...
journal_title:International journal of clinical practice
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2010-07-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
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journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:
更新日期:1998-04-01 00:00:00
abstract:AIMS:To investigate the diagnostic value of the International Prostate Symptom Score (IPSS) voiding-to-storage subscore ratio (IPSS-V/S) in male lower urinary tract symptoms (LUTS). METHODS:A total of 253 men with LUTS were enrolled from January 2005 to July 2010. The voiding (IPSS-V) and storage IPSS (IPSS-S) subscor...
journal_title:International journal of clinical practice
pub_type: 杂志文章
doi:10.1111/j.1742-1241.2011.02638.x
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:10.1111/j.1742-1241.2008.01941.x
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journal_title:International journal of clinical practice
pub_type: 杂志文章,meta分析,评审
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更新日期:2010-07-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1742-1241.2007.01574.x
更新日期:2007-11-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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pub_type: 杂志文章,meta分析,评审
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:International journal of clinical practice
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journal_title:International journal of clinical practice
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更新日期:2016-08-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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journal_title:International journal of clinical practice
pub_type: 杂志文章,评审
doi:
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journal_title:International journal of clinical practice
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更新日期:2007-04-01 00:00:00
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journal_title:International journal of clinical practice
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章,多中心研究
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更新日期:2009-03-01 00:00:00
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