Abstract:
OBJECTIVE:We aimed to assess the feasibility, safety, and efficacy of radiofrequency (RF) ablation for the treatment of large (≥5 cm in greatest diameter) hepatic hemangiomas. METHODS:Thirty-six patients (15 male, 21 female; mean age 50 years) with 41 hepatic hemangiomas ≥5 cm in diameter were enrolled and treated with RF ablation attributable to the presence of enlargement tendency and/or persistent hemangioma-associated symptoms. Twenty patients had 24 hemangiomas <10 cm, and 16 patients had 17 hemangiomas ≥10 cm. Technical success, complications related to RF ablation, completed ablation, symptom relief, change in size of ablation zone, and recurrence of the residual tumor were analyzed. RESULTS:Of the 41 hemangiomas with a mean diameter 10 ± 4 cm (range, 5-22 cm), 26 subcapsular lesions were treated with a laparoscopic approach, and 15 lesions located in liver parenchyma underwent a computed tomography-guided percutaneous approach. RF ablation was performed successfully in all patients. There were 62 complications related to the ablation in 22 patients, including 6 of 20 patients with hemangiomas <10 cm and all the 16 patients with hemangiomas ≥10 cm. According to the Dindo-Clavien classification, 2 complications (lower esophageal fistula and acute respiratory distress syndrome, Grade III and Grade IV, respectively) were major in 2 patients with hemangiomas ≥10 cm; all the other were minor in 20 patients (Grade I). All the complications were recovered by conservative treatment. Thirty-eight (93%) of 41 hepatic hemangiomas were ablated completely, including all the 24 lesions <10 cm and 14 of 17 lesions ≥10 cm. All the symptoms related to hemangiomas disappeared (n = 22) or were ameliorated (n = 4) after ablation. The mean diameter of ablation zone was decreased to 6 ± 3 cm (2-12 cm) in a mean follow-up period (X ± SD) of 15 ± 6 months (range, 6-24 months), without recurrence or enlargement of the 3 residual tumors. CONCLUSION:The present study supports RF ablation as an alternative treatment for hepatic hemangiomas ≥5 cm (but smaller than 10 cm) for the low risk of complications and likelihood of complete ablation, but, in contrast, RF ablation appears to be an inappropriate method for hepatic hemangiomas ≥10 cm because of the high occurrence rate of complications.
journal_name
Surgeryjournal_title
Surgeryauthors
Gao J,Ke S,Ding XM,Zhou YM,Qian XJ,Sun WBdoi
10.1016/j.surg.2012.06.004subject
Has Abstractpub_date
2013-01-01 00:00:00pages
78-85issue
1eissn
0039-6060issn
1532-7361pii
S0039-6060(12)00291-7journal_volume
153pub_type
杂志文章相关文献
SURGERY文献大全abstract:BACKGROUND:The effect of trehalose on the preservation of canine lungs was studied with the use of Euro-Collins solution (ECS). METHODS:In group 1, five lungs were perfused and preserved with a modified ECS in which trehalose (35.0 gm/L) was used instead of glucose. In group 2, six lungs were perfused and preserved wi...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Serial thickness measurements of the glomerular basement membrane were performed over a 24-month period in four groups of inbred male Lewis rats. Group I consisted of normal animals age-matched to the remaining experimental groups. In groups II, III, and IV, diabetes was induced by intravenous alloxan (42 to 44 mg/kg)...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1980-07-01 00:00:00
abstract::The incidence and management of complications of injection sclerotherapy are reviewed in 304 consecutive patients with esophageal varices followed up prospectively for a 10-year period. The 304 patients were injected on 1336 occasions. Three hundred eleven local esophageal complications occurred in 140 patients (compl...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract:BACKGROUND:Anastomotic leakage represents a major complication after anterior resection of the rectum. The incidence of anastomotic leakage varies considerably among clinical studies in part owing to the lack of a standardized definition of this complication. The aim of the present article was to propose a definition a...
journal_title:Surgery
pub_type: 杂志文章,评审
doi:10.1016/j.surg.2009.10.012
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:The management of patients with a complete clinical response after neoadjuvant therapy for rectal adenocarcinoma is controversial. Those who advocate for resection point out the inaccuracy of N-staging with current imaging modalities. The objective of this study is to determine the impact of residual nodal i...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2019.03.026
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Groin hernia repair occasionally leads to severe chronic pain associated with entrapped or damaged nerves. Conservative treatment is often unsuccessful. Selective neurectomy may be effective, but long-term results are scarce. The authors assessed the long-term efficacy of surgical neurectomy for chronic, pos...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2009.08.008
更新日期:2010-02-01 00:00:00
abstract::Hemolytic uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia, and acute renal failure, usually in children under 10 years of age. Gastrointestinal symptoms, including abdominal pain and bloody diarrhea, frequently precede the onset of renal failure. It has not been generally appreciated that ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1979-03-01 00:00:00
abstract:BACKGROUND:With over 110,000 bariatric operations performed in the United States annually, it is important to understand the biochemical abnormalities causing endocrine dysfunction associated with these procedures. Here we compare 2 malabsorptive procedures, duodenal switch and Roux-en-Y gastric bypass, to determine th...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2016.08.046
更新日期:2017-03-01 00:00:00
abstract::Ischemia and reperfusion lead to eicosanoid- and neutrophil (PMN)-dependent injury. This study tests the role of ischemia-induced lipoxygenase activity in mediating PMN activation and diapedesis. Anesthetized rabbits (n = 8) underwent 3 hours of bilateral hindlimb ischemia. At 10 minutes of reperfusion, leukotriene B4...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
abstract:BACKGROUND:Our aim was to identify differential expression of genes in hepatocellular carcinoma (HCC) with the ultimate goal of discovering novel diagnostic and therapeutic targets. METHODS:We examined differences in gene expression between HCC and noncancerous liver tissue using a cDNA array with probes for 15,843 ge...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.12.007
更新日期:2011-06-01 00:00:00
abstract::This retrospective study evaluated quantification of skin fluorescein delivery by fiberoptic fluorometry as a means of predicting the healing potential of an amputation site. Fluorometry uses a dual-channel fiberoptic light guide--one channel transmits blue light to excite the fluorescein in the skin under study, and ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
abstract::A patient who underwent jejunoileal bypass for morbid obesity developed servere renal failure associated with hyperoxaluria and renal oxalosis. Renal function improved and oxalate excretion decreased following hemodialysis and restoration of gastrointestinal continuity. ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1977-11-01 00:00:00
abstract::Metabolic alkalosis secondary to chloride depletion, especially following gastrointestinal surgery and associated with acute renal failure, is a frequent clinical occurrence. Management of the resultant acid-base disturbance mandates chloride replacement. The presence of oliguria limits the choice of accompanying cati...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1975-10-01 00:00:00
abstract:BACKGROUND:Gross vascular invasion is a well-established prognostic indicator in hepatocellular carcinoma (HCC), but the biological significance of microscopic invasion remains unclear. METHODS:Curatively resected primary HCCs were classified retrospectively into 3 groups: HCCs without vascular invasion (V0), HCCs wit...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2009.09.037
更新日期:2010-03-01 00:00:00
abstract::Nelson's syndrome--progressive cutaneous hyperpigmentation with x-ray film evidence of an expanding pituitary tumor--is now a well-recognized sequela of bilateral adrenalectomy for Cushing's disease. It is estimated to occur in 8% to 38% of adults. Because Cushing's disease is rare in children, a higher incidence of N...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1984-12-01 00:00:00
abstract:INTRODUCTION:A diverting stoma is often performed at the time of low anterior resection (LAR) for rectal cancer after neoadjuvant chemoradiation (nCRT) to protect the anastomosis. The aim of this study was to compare surgical outcomes in large cohorts of mid-high rectal cancer patients undergoing LAR after nCRT with an...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2015.02.026
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:An altered immune microenvironment may contribute to papillary thyroid cancer development, as immune infiltrates are identified postoperatively in many papillary thyroid cancer cases with or without diagnosed thyroiditis. Oxygen radicals, endogenous or inflammation-induced, can generate DNA damage, which cau...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2019.02.024
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Repeat hepatectomy is a feasible treatment modality for intrahepatic recurrence after hepatectomy of hepatocellular carcinoma, yet the survival benefit remains ill-defined. The objective of the current study was to define long-term, oncologic outcomes after repeat hepatectomy among patients with early and la...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2019.11.005
更新日期:2019-12-23 00:00:00
abstract:BACKGROUND:Although hepatic resection is the most reliable treatment for hepatocellular carcinoma, impaired liver function because of cirrhosis or chronic hepatitis contributes to relatively high rates of postoperative complications. We have reviewed a series of hepatectomies at our institution and investigated risk fa...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::Several clinical studies have documented an increased incidence of gallstones after truncal vagotomy. Previous laboratory studies, however, have failed to establish a clear mechanism for this phenomenon. Whereas lithogenic bile is a prerequisite for cholesterol cholelithiasis, gallbladder stasis has also been shown to...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1981-08-01 00:00:00
abstract::Heterotopic rat heart allografts were performed in 35 rats. At intervals after transplantation, rats were killed and tissue concentrations of immunoassayable prostaglandin E (PGE) were measured in the native heart, transplanted heart, spleen, and thymus. A significant increase in allograft PGE activity was observed at...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1975-10-01 00:00:00
abstract:BACKGROUND:Vaccination of tumor-bearing animals with tumor cells genetically engineered to secrete cytokines including interleukin-2 (IL-2) and interferon-gamma (IFN-gamma) has been shown to induce effective tumor-specific immune responses capable of inhibiting local and metastatic disease. Previous unsuccessful attemp...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/s0039-6060(96)80285-6
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND:Although there exists robust literature on mortality-associated factors in burn patients, it is not known how electronic medical records affect outcomes. Using burn injury as a surgical care model of information and communication, we hypothesized that functionality and interoperability of the electronic medi...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2018.07.010
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Hemorrhage-induced activation of endothelial cell Na+/H+ -exchanger results in cellular swelling, which physically impedes capillary filling and compromises gut perfusion. We hypothesized that correction of the vascular volume deficit by conventional resuscitation does not improve capillary filling unless ce...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2007.08.007
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Results of the conservative treatment of renal cell carcinomas arising in functional renal transplants are unknown compared to transplant nephrectomy. Only small series or case reports have been reported. METHODS:Data were collected from 32 transplantation centers nationwide on cases of de novo tumors in fu...
journal_title:Surgery
pub_type: 杂志文章,多中心研究
doi:10.1016/j.surg.2016.01.022
更新日期:2016-07-01 00:00:00
abstract::The Consortium of American College of Surgeons-Accredited Education Institutes was created to explore new opportunities in simulation-based surgical education and training beyond the scope of individual accredited institutes. During the Third Annual Meeting of the Consortium of American College of Surgeons-Accredited ...
journal_title:Surgery
pub_type:
doi:10.1016/j.surg.2010.11.010
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Hepatocellular carcinoma (HCC) is among the most common malignant neoplasms worldwide. Only few data on HCC in noncirrhotic livers without viral hepatitis in Western countries are available. The purpose of this study was to define the outcomes and potential prognostic factors associated with survival after h...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2012.09.015
更新日期:2013-04-01 00:00:00
abstract:UNLABELLED:In patients undergoing pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma (PC), conversion to total pancreatectomy (TP) may be necessary to achieve R0 resection. HYPOTHESIS:We sought to examine the oncologic benefit of conversion of PD to TP to achieve an R0 resection in patients with an isolated po...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2007.07.016
更新日期:2007-10-01 00:00:00
abstract::Two patient groups were studied to determine the need to preserve the greater saphenous vein during femoral outflow reconstruction for later aortocoronary bypass procedures. First, 74 patients were followed to the time of death or to a minimum of 5 years after femoral outflow reconstruction was performed. Only four pa...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1984-04-01 00:00:00
abstract:PURPOSE:Enhancer of zeste homologue 2 (EZH2), a component of the chromatin modification protein complex, is upregulated in pancreatic ductal adenocarcinoma (PDAC), whereas loss of p53 and its downstream target, p21(waf1/cip1), is also observed frequently. We sought to investigate the role of the p53-p21(waf1/cip1) path...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2013.06.041
更新日期:2013-10-01 00:00:00