Abstract:
:The emergence of drug-resistant tuberculosis (TB) is an increasing problem which adversely affects patient care and public health. This study aimed to determine the rates and patterns of primary anti-TB drugs resistance in Najran, Southwestern Saudi Arabia. The study included 80 smear-positive new pulmonary TB patients. Sputum samples were cultured on Lowenstein-Jensen and Middle-Brook 7H10 media. Mycobacterium tuberculosis susceptibility testing was done by the conventional agar proportion method for isoniazide (INH), rifampicin (RIF), streptomycin (SPM) and ethambutol (EMB). Out of the 68 M. tuberculosis isolates, 42 (61.8%) were sensitive to all 4 drugs and 26 (38.2%) were resistant to one or more drugs. The most common resistance was found to INH (33.8%), followed by RIF (23.5%), SPM (13.2%) and EMB (2.9%). Eight (11.8%) isolates were resistant to one drug, 14 (20.6%) were resistant to 2 drugs, 3 (4.4%) were resistant to 3 drugs and one (1.5%) was resistant to 4 drugs. Multi-drug resistant (MDR) isolates were found in 14 (20.6%) cases. In conclusion, the primary resistance rate to four first-line anti-tuberculous drugs and MDR-TB rate are worryingly high, representing an alarming situation in Najran. Further studies are necessary for continuous surveillance of M. tuberculosis resistance patterns.
journal_name
J Infect Public Healthjournal_title
Journal of infection and public healthauthors
Asaad AM,Alqahtani JMdoi
10.1016/j.jiph.2012.03.005subject
Has Abstractpub_date
2012-08-01 00:00:00pages
281-5issue
4eissn
1876-0341issn
1876-035Xpii
S1876-0341(12)00058-5journal_volume
5pub_type
杂志文章abstract::Hand washing is widely accepted as the cornerstone of infection control in the intensive care unit (ICU). Nosocomial infections are frequently viewed as indicating poor compliance with hand washing guidelines. To determine the hand hygiene (HH) compliance rate among healthcare workers (HCWs) and its effect on the noso...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2012.09.014
更新日期:2013-02-01 00:00:00
abstract::Toxocarosis is a zoonotic parasitic disease transmitted from companion animals to humans. Environmental contamination with Toxocara eggs is considered to be the main source of human infections. In Portugal, knowledge regarding the current situation, including density, distribution and environmental contamination by To...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2017.05.002
更新日期:2018-01-01 00:00:00
abstract::MERS-coronavirus infection is currently responsible for considerable morbidity and mortality in Saudi Arabia. Understanding its burden, as an emerging infectious disease, is vital for devising appropriate control strategies. In this study, the burden of MERS-CoV was estimated over 31months period from June 6, 2012 to ...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.11.016
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Spontaneous bacterial peritonitis (SBP) is a potentially lethal complication of cirrhosis. It is probably the most characteristic infectious complication of cirrhosis. AIM:The aim of this study was to evaluate the bacterial and fungal causes of SBP in Egyptian population. Furthermore to predict the occurren...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2011.06.002
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:Laboratory testing and reporting are error-prone and redundant due to repeated, unnecessary requests and delayed or missed reactions to laboratory reports. Occurring errors may negatively affect the patient treatment process and clinical decision making. Evaluation on laboratory testing and Laboratory Info...
journal_title:Journal of infection and public health
pub_type: 杂志文章,评审
doi:10.1016/j.jiph.2016.08.014
更新日期:2016-01-01 00:00:00
abstract::To study the nursing effects of different CT angiography (CTA) technology-based nursing methods on patients with coronary artery heart diseases (CHD), CHD patients treated in Dongying People's Hospital were selected as the research objects and were divided into the control group and the observation group. Different co...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.06.023
更新日期:2020-12-01 00:00:00
abstract::Leprosy is a chronic disease caused by Mycobacterium leprae. Although the occurrence of leprosy has declined in Saudi Arabia, it has not yet been eradicated. To our knowledge, this descriptive retrospective study is the first to assess the clinical presentation of leprosy at the time of diagnosis in Saudi Arabia. All ...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2015.12.015
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Coronavirus disease 2019 (COVID-19) has been highly epidemic in China since January 2020. Rapid detection of the causative agent, severe acute respiratory coronavirus-2 (SARS-CoV-2), is very important due to its high rate of infectivity. This study aimed to clarify the epidemiology and clinical characteristi...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2020.05.003
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Norovirus (NoV) is recognized as a leading global cause of viral acute gastroenteritis (AGE). To better understand the prevalence and genotypic patterns of NoV infection in Southeast China, we conducted a retrospective study of diarrheal syndrome surveillance of NoV and analyzed the epidemiological character...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.06.006
更新日期:2020-01-01 00:00:00
abstract::Brucellosis is a common zoonotic disease throughout the world. Brucella spp. transmit to humans through contact with fluids of infected animals, especially sheep, cattle, and goats. It is also transmitted by ingestion of fluid-derived products of infected animals, such as unpasteurized milk and cheese. Brucella spp. c...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2014.07.004
更新日期:2014-11-01 00:00:00
abstract:INTRODUCTION:Middle East respiratory syndrome coronavirus (MERS-CoV) belongs to the family Coronaviridae, and is named for the crown-like spikes on its surface. The clinical presentation of MERS-CoV infection ranges from asymptomatic to very severe disease, and the classical presentation includes fever, cough chills, s...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2018.02.001
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Few studies have reported the uptake of health preventive measures among Hajj pilgrims from Saudi Arabia. Yet, none of these studies have explored their perceptions of health risks at Hajj or pretravel health-advice-seeking behavior. METHODS:A cross-sectional survey conducted among Hajj pilgrims from Saudi ...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.04.007
更新日期:2019-01-01 00:00:00
abstract::The objective of the study was to determine the level of Knowledge, Attitude and Practice (KAP) of patients attended dental clinics at King Abdulaziz University Hospital (KAUH) regarding cross infections and infection control in dentistry. A cross-sectional study was conducted among 225 patients who attended the denta...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2016.06.002
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to estimate the attributable risk for all-cause mortality in hypertensive adults living in Beijing, China. METHODS:We conducted a prospective cohort study on the basis of the disease risk prediction model, which included 3006 hypertensive patients aged 50 and over who participated ...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.12.010
更新日期:2020-09-01 00:00:00
abstract::Carbapenemase-producing Enterobacteriaceae have been steadily spreading worldwide during the last decade. Nine patients were identified prospectively and were followed during their hospitalization course to identify the epidemiology, clinical profiles and outcomes. These patients had one or more cultures positive for ...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2017.05.004
更新日期:2017-01-01 00:00:00
abstract::This study compares the factors, which influence individuals from the countries of China, Japan and South Korea to obtain any type of influenza vaccines and their perceived concerns about the new strain of the influenza - pandemic (H1N1) 2009. The data analyzed was from the East Asian Social Survey (EASS), Cross-Natio...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2016.06.004
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:In this study, expression of cancer stem cells (CSCs)-related factor-Sex-determining region of Y chromosome-related high-mobility-group box 2 (SOX2) and anti-apoptotic specific factor- Survivin in salivary adenoid cystic carcinoma (SACC) was detected to provide important clues for effective SACC prevention an...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.03.015
更新日期:2019-01-01 00:00:00
abstract::Rhinocerebral or sinopulmonary mucromycosis is a well-recognized human fungal infection found among immunocompromised and diabetic patients. However, the infection is rare among immunocompetent hosts. We are reporting the case of an adult immunocompetent male patient working as an air-conditioning technician. The pati...
journal_title:Journal of infection and public health
pub_type: 杂志文章,评审
doi:10.1016/j.jiph.2011.10.002
更新日期:2012-03-01 00:00:00
abstract::This study focused on 77 isolates of Salmonella enterica serotype Enteritidis collected during 2009 to 2013 from healthy and sick chickens and environmental farm samples in Tunisia. Resistance to 14 antimicrobials and the encoding genes were analyzed. 66, 26, 6.5, 3.9 and 1.3% were pan-susceptible or showed resistance...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2017.01.012
更新日期:2017-01-01 00:00:00
abstract::The human stomach is colonized by diverse bacterial species. The presence of non-Helicobacter pylori bacteria in urease-positive biopsies of individuals has been reported. Bacteria belonging to the Ochrobactrum genus have been documented in the human gastric niche. The co-occurrence of Ochrobactrum spp. with H. pylori...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2016.04.013
更新日期:2017-01-01 00:00:00
abstract::Listeria monocytogenes is among the most important foodborne pathogens, which can be isolated from bird feces. The aim of this study was to examine the prevalence, genotypes, virulence factors and drug-resistance characteristics of L. monocytogenes isolated from the black-headed gull in Kunming, China. Serotypes and v...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2017.03.003
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:Pseudomonas aeruginosa (member of ESKAPE group) is predominantly responsible for emerging nosocomial infections and poses serious health concern due to ever-increasing drug resistance trends. The current study investigates the prevalence of such highly resistant P. aeruginosa in major hospital settings and...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.08.019
更新日期:2020-04-01 00:00:00
abstract::Dengue hemorrhagic fever is transmitted through a bite by a dengue -infected Aedes aegypti mosquito. It was first reported in the mid -20th century in Thailand, and since then its epidemiology has been of great concern and has spread all across the country. The alarming incidence of dengue posed a serious threat to hu...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2017.01.016
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:Despite the advancement in diagnostic modalities of sepsis, it is still a leading cause of morbidity and mortality. Differentiation between sepsis and non-infectious disease states remains a diagnostic challenge. Procalcitonin (PCT) is useful for the diagnosis of sepsis but it varies in cut-off ranges at d...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2018.11.004
更新日期:2019-01-01 00:00:00
abstract::Idiopathic granulomatous mastitis (IGM) is a benign chronic inflammatory disorder of the breast tissue, with unknown etiology. IGM is extremely rare among male gender. In this case report, we present a male patient with superficial high grade bladder cancer, who was complaining of a palpable mass in his right breast f...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.09.006
更新日期:2020-05-01 00:00:00
abstract::Leptospires are spirochetes of Leptospira genus. Infection in humans occurs by penetration into the mucous membranes, or into the skin (small wounds or abrasions). Humans are infected when they contact with urine of rodents, the main reservoirs. We aimed to evaluate the presence of anti-Leptospira spp antibodies and l...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.02.001
更新日期:2019-01-01 00:00:00
abstract::Salmonella osteomyelitis in immunocompetent adults is uncommon. It usually has a diaphyseal location or present as spondylitis. Metaphyseal affection is extremely rare. A 51-year-old male presented with refractory knee pain. Plain X-rays showed a rounded osteolytic lesion in the proximal tibia without marginal scleros...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2013.07.004
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Plasmodium vivax malaria accounts for 80% of the malaria cases in Delhi, India. The gene merozoite surface protein 3 alpha (MSP3α) is highly polymorphic and has been used as marker in many P. vivax population studies. METHODS:MSP3α has been used to assess the genetic diversity of P. vivax samples from Delhi...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.01.068
更新日期:2019-01-01 00:00:00
abstract::In the last few years, Cryptococcus laurentii infections have increased, particularly in immunocompromised patients. Here we report the first case of C. laurentii fungemia in low birth weight preterm infant from India. A preterm neonate was admitted for feeding intolerance and respiratory distress. Blood culture ascer...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2018.04.012
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Escherichia coli sequence type 131 is an important multidrug resistant clone responsible from more than half of ESBL-producing E.coli isolates. Aim of this study was to investigate the presence of O25b-ST131 clone, CTX-M-15 and CTX-M-1 genes in the E. coli strains isolated from both hospital and community ac...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.02.017
更新日期:2019-01-01 00:00:00