Abstract:
BACKGROUND:Escherichia coli sequence type 131 is an important multidrug resistant clone responsible from more than half of ESBL-producing E.coli isolates. Aim of this study was to investigate the presence of O25b-ST131 clone, CTX-M-15 and CTX-M-1 genes in the E. coli strains isolated from both hospital and community acquired UTIs by real-time PCR and to reveal molecular epidemiological data. METHODS:Non-duplicate E. coli (n = 101) strains isolated from UTI patients were included. Bacterial identifications were performed with VITEK Compact. Antimicrobial susceptibility tests, phenotypic ESBL and E-tests were performed conventionally. Real-time PCR was utilized to detect presence of O25b-ST131 clone, blaCTX-M-15 and blaCTX-M-1. RESULTS:O25b-ST131 clone, CTX-M-1 and CTX-M-15 were detected in 22%, 73%, 37% in UTIs, respectively. Presence of O25b-ST131 clones and CTX-M-1 genes among E. coli strains isolated from inpatients were found statistically higher than outpatients. The most effective choice was found to be fosfomycin and nitrofurantoin in outpatients and inpatients, respectively. The MIC90 values of Amikacin, Cefotaxime, Cefepime and Ciprofloxacin were higher in inpatients than in oupatients, whereas Cefotaxime and Ciprofloxacin MIC50 values were found to be higher in inpatients than in outpatients. The highest increase of MIC90 values was observed in O25b-ST131, CTX-M-1 and CTX-M-15 coexistence. CONCLUSION:The presence of O25b-ST131 clone, CTX-M-1 and CTX-M-15 genes in E. coli strains in patients with UTI has been revealed. In the presence of the O25b-ST131 clone, a significant increase was observed in the ciprofloxacin MIC values indicating the importance of monitorization of the clone using molecular epidemiology.
journal_name
J Infect Public Healthjournal_title
Journal of infection and public healthauthors
Demirci M,Ünlü Ö,İstanbullu Tosun Adoi
10.1016/j.jiph.2019.02.017subject
Has Abstractpub_date
2019-01-01 00:00:00pages
640-644issue
5eissn
1876-0341issn
1876-035Xpii
S1876-0341(19)30088-7journal_volume
12pub_type
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journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2015.06.004
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abstract:AIM:To assess the risk factors for surgical site infection and the effects of selected infection control measures on surgical site infection rates in a general surgery unit. METHODS:Surgical site infection rates and adherence to infection control measures were observed in a general surgery unit. RESULTS:In multivaria...
journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
pub_type: 杂志文章,多中心研究
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abstract::In the last few years, Cryptococcus laurentii infections have increased, particularly in immunocompromised patients. Here we report the first case of C. laurentii fungemia in low birth weight preterm infant from India. A preterm neonate was admitted for feeding intolerance and respiratory distress. Blood culture ascer...
journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2017.06.012
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
pub_type: 杂志文章,多中心研究
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journal_title:Journal of infection and public health
pub_type: 杂志文章,评审
doi:10.1016/j.jiph.2010.07.001
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journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2013.05.006
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journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2013.07.004
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journal_title:Journal of infection and public health
pub_type: 杂志文章,评审
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abstract::Zika virus (ZIKV), an Aedes mosquito-borne flavivirus, has captured public health attention worldwide. Initially, the virus was reported in Africa and Asia. However, the outbreak of ZIKV in Brazil and the United States of America demonstrated the global health risk. Symptoms of ZIKV infection vary from mild fever, ras...
journal_title:Journal of infection and public health
pub_type: 杂志文章,评审
doi:10.1016/j.jiph.2019.05.004
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abstract:OBJECTIVE:In this study, expression of cancer stem cells (CSCs)-related factor-Sex-determining region of Y chromosome-related high-mobility-group box 2 (SOX2) and anti-apoptotic specific factor- Survivin in salivary adenoid cystic carcinoma (SACC) was detected to provide important clues for effective SACC prevention an...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.03.015
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journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2018.02.006
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abstract::Crack cocaine users represent a target group for hepatitis B vaccination. We evaluate the HBV epidemiology, immunization status and compliance with a super-accelerated vaccination schedule among in-treatment crack cocaine users in central Brazil. Six hundred in-treatment crack cocaine users were interviewed, and serum...
journal_title:Journal of infection and public health
pub_type: 杂志文章
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abstract:BACKGROUND:Plasmodium vivax malaria accounts for 80% of the malaria cases in Delhi, India. The gene merozoite surface protein 3 alpha (MSP3α) is highly polymorphic and has been used as marker in many P. vivax population studies. METHODS:MSP3α has been used to assess the genetic diversity of P. vivax samples from Delhi...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.01.068
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journal_title:Journal of infection and public health
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journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2015.04.027
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abstract::Leprosy is a chronic disease caused by Mycobacterium leprae. Although the occurrence of leprosy has declined in Saudi Arabia, it has not yet been eradicated. To our knowledge, this descriptive retrospective study is the first to assess the clinical presentation of leprosy at the time of diagnosis in Saudi Arabia. All ...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2015.12.015
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Coronavirus disease 2019 (COVID-19) has been highly epidemic in China since January 2020. Rapid detection of the causative agent, severe acute respiratory coronavirus-2 (SARS-CoV-2), is very important due to its high rate of infectivity. This study aimed to clarify the epidemiology and clinical characteristi...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2020.05.003
更新日期:2020-06-01 00:00:00
abstract::Diagnosis of MERS-Cov still a major concern in most of daignostic laboratories. To date the Real-time Polymerase Chain reaction (RT-PCR) is the mainstay for diagnosis of MERS-CoV. RT-PCR has limitations, including a long turnaround time and lack of common measurements and correlations with Viral Load (VL). It is recom...
journal_title:Journal of infection and public health
pub_type: 杂志文章,评审
doi:10.1016/j.jiph.2016.04.005
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abstract::We report a case of Listeria meningitis related to mantle cell lymphoma. A clinical pharmacist adjusted repeatedly the patient's anti-infective therapeutic regimen by analyzing the pharmacologic and pharmacokinetic characteristics of antibacterial drugs (such as cefotaxime, meropenem, etc.) due to the patient's repeat...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.04.010
更新日期:2019-01-01 00:00:00
abstract::The ability of Staphylococcus aureus to form biofilm is considered to be a major virulence factor influencing its survival and persistence in both the environment and the host. Biofilm formation in S. aureus is most frequently associated with production of polysaccharide intercellular adhesion by ica operon-encoded en...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2017.01.004
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Natural products derived from marine microbes have more potential toward to treatment of various diseases. Among the microbes, the secondary metabolites recovered from the marine actinomycetes were more added values. OBJECTIVE:A promising antimicrobial metabolite producing filamentous actinomycete SCA-7 rec...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2019.07.002
更新日期:2020-01-01 00:00:00
abstract::We evaluated the effectiveness of inactivated influenza vaccine in persons aged ≥45 years with co-morbidities (including essential hypertension) likely to have prompted consideration of prophylactic statin therapy. Using case-control analyses, we measured the impact of vaccination on General Practitioner (GP) reported...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2010.09.007
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVES:To assess the impact of a multidimensional infection control approach on the reduction of catheter-associated urinary tract infection (CAUTI) rates in adult intensive care units (AICUs) in two hospitals in the Philippines that are members of the International Nosocomial Infection Control Consortium. MATERIA...
journal_title:Journal of infection and public health
pub_type: 杂志文章
doi:10.1016/j.jiph.2013.03.002
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