[Therapeutic strategies in dry eye disease--a survey of possible substitution therapies and causal therapeutic approaches].

Abstract:

:Substitution therapy with artificial tears is the standard in dry eye disease. Nowadays there are a vast variety of different preparations. This article gives an overview of both new and old approaches to substitution therapy (one-, two- and three-phase preparations) as well as opportunities for the causal treatment. Here, we provide dry eye treatment options regarding sophisticated disease subgroups, classifications concerning the affected tear film layer (aqueous, mucinous or lipid phase), and immunological dysfunctions.

journal_name

Klin Monbl Augenheilkd

authors

Zimmermann N,Erb C

doi

10.1055/s-0032-1315379

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

1198-203

issue

12

eissn

0023-2165

issn

1439-3999

journal_volume

229

pub_type

杂志文章,评审
  • [Erythropsia following exposure to toluene].

    abstract::A patient who had been exposed to toluol for ten years developed acute erythropsia. The examinations leading to the diagnosis and the possible differential diagnosis are discussed. ...

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    doi:10.1055/s-2008-1046214

    authors: Prünte-Glowazki A

    更新日期:1990-05-01 00:00:00

  • [Comparison of different optical techniques for determination of the dimensions of anterior ocular segment].

    abstract:BACKGROUND:The evaluation of the anterior ocular chamber sections along the optical axis/axis of vision has been carried out using single-line partial coherence interferometry for many years. Now, new technologies such as the Scheimpflug-technique of the Pentacam (Oculus Optikgeräte GmbH, Wetzlar) and the optical coher...

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    doi:10.1055/s-0028-1109367

    authors: Lange S,Haigis W,Grein HJ,Schütze J

    更新日期:2009-06-01 00:00:00

  • [Tear film diagnosis in contact lens wearers].

    abstract::Contact lenses have an intimate relationship with the precorneal tear film and it is important to attempt to prognosticate the likelihood of successful contact lens wear by evaluating, both quantitative and qualitative aspects of the precorneal tear film. Aspects of history diagnostic methods and general aspects which...

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    doi:10.1055/s-2008-1046269

    authors: Lemp MA,Gold JB

    更新日期:1990-09-01 00:00:00

  • [Clinical and fluorescein angiography findings in patients with retinal vein occlusion. A unicenter study of 211 patients].

    abstract::Between january 1986 and december 1989 we prospectively studied 211 patients with branch retinal vein occlusion (BRVO). Documented by fundus photography and fluorescein angiography clinical and angiographic findings were analysed. The age ranged from 28 to 83 with a mean of 63 years. 104 (48.8%) patients were male, 10...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:10.1055/s-2008-1045901

    authors: Lang GE,Freissler K

    更新日期:1992-10-01 00:00:00

  • Latanoprost is a vasoconstrictor in isolated porcine ciliary arteries.

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    doi:10.1055/s-2001-15904

    authors: Brogiolo G,Flammer J,Haefliger IO

    更新日期:2001-05-01 00:00:00

  • [Survival after treatment for malignant choroidal melanoma: comparison between conservative therapy (Ru106/Rh106 applicator) and enucleation with and without postoperative irradiation to the orbit; 1960 to 1979].

    abstract::The survival rate was calculated using the life table method in 1,501 patients suffering from choroidal melanomas and treated in 10 eye hospitals in the GDR between 1960 and 1979. The results of treatment by (1) enucleation, (2) enucleation with postoperative irradiation of the orbit and (3) local irradiation with 106...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1054399

    authors: Kiehl H,Kirsch I,Lommatzsch P

    更新日期:1984-01-01 00:00:00

  • [Basic in vitro studies on VEGF inhibition with aflibercept: similarities and differences to other VEGF-binding therapeutic proteins].

    abstract::Patients suffering from various retinal diseases benefit from therapies directed against the vascular endothelial growth factor (VEGF). Aflibercept (Eylea) is another VEGF-binding protein available for intravitreal injection, in addition to the antibody bevacizumab (Avastin) and the F(ab) fragment ranibizumab (Lucenti...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0034-1383142

    authors: Lang GE,Lang GK,Deissler HL

    更新日期:2015-03-01 00:00:00

  • [Potential of Adaptive Optics for the Diagnostic Evaluation of Hereditary Retinal Diseases].

    abstract::The use of adaptive optics in ophthalmoscopy is a breakthrough technological achievement. With AO ophthalmoscopes, the microscopic retinal structure can be visualised non-invasively and on a cellular level, allowing for cellular scale imaging of the retinal nerve fibre layer, the smallest retinal capillaries, rod and ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0043-100631

    authors: Reiniger JL,Domdei N,Pfau M,Müller PL,Holz FG,Harmening WM

    更新日期:2017-03-01 00:00:00

  • [Necrotizing sclerokeratitis following cataract extraction].

    abstract::A number of cases of necrotic sclerokeratitis following eye surgery have been reported in recently published literature. The condition was presumably triggered by surgical inflammation and caused by localized occlusive vasculitis: in one case deposits of immune complexes in vessel walls were demonstrated. The authors ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:10.1055/s-2008-1050312

    authors: Gregersen E,Jørgensen JS

    更新日期:1988-12-01 00:00:00

  • [A contribution of the course of vitreous haemorrhage (author's transl)].

    abstract::After some basic remarks about the physiological adhesions of the vitreous body to its surrounding structures in the anterior part of the eye (lens, ciliary body, pars plana) and the posterior part of the eye (macular, optic disc) the general history of bleeding in the vitreous body and the different possibilities of ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Plange H,Speiser P

    更新日期:1976-10-01 00:00:00

  • [Pyoderma vegetans of the eye-lid (author's transl)].

    abstract::A cases of Pyoderma vegetans attacking only the outer skin of the eyelid and leaving free the conjunctiva is reported. The diagnosis of this rare condition, belonging to the pemphigus diseases, depends on clinical course and especially on histological investigation. The aetiology of Pyoderma vegetans still remains unk...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Uthoff D,Teichmann KD,Pülhorn G

    更新日期:1978-08-01 00:00:00

  • [Quiz on an unusual orbital masquerade syndrome].

    abstract:BACKGROUND:After consulting the here presented CT-images of the orbit, the question was raised whether the ocular bulbus was really enucleated or the anamnesis was wrong and a lymphoma existed in the orbit. We will therefore discuss a case of a special follow-up after an enucleation with implantation of a "Bangerter Pl...

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    doi:10.1055/s-2008-1035393

    authors: Gloor B,Schuknecht B,Valavanis A

    更新日期:1995-12-01 00:00:00

  • [Choice of the lens implant model].

    abstract::Report on 530 lens implantation procedures performed in the years from 1981 to 1985. Different complications with different lens models are mentioned, in particular cystoid macular edema, subluxation or luxation of the artificial lens, vitreous complication, secondary cataract, and retinal detachment. A comparison was...

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    doi:10.1055/s-2008-1054355

    authors: Hanselmayer H

    更新日期:1985-11-01 00:00:00

  • [The Mannheim lens: a provisional cataract lens for one-eyed aphakic patients (author's transl)].

    abstract::Description of a tailor-made dressing with a built-in cataract lens which gives the one-eyed aphakic patient vision from the first postoperative day. ...

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    authors: Werner W,Martus H,Liesenhoff H

    更新日期:1980-06-01 00:00:00

  • [Nosocomial pseudomonas aeruginosa-associated keratitis in soft contact lens wearer].

    abstract:BACKGROUND:Pseudomonas aeruginosa is the most common cause of bacterial-associated keratitis in soft contact lens wearers, due to wrong use of soft contact lenses. Problems are often severe corneal ulcers and even corneal perforations. We report on a soft contact lens wearer with credibly correct use of soft contact le...

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    authors: Grünauer-Kloevekorn C,Wilhelm F,Duncker GI,Hammer T

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  • Spontaneous orbital haemorrhage into the lateral rectus muscle.

    abstract:BACKGROUND:Spontaneous orbital haemorrhage can occur at any age. The clinical presentation is often dramatic with acute painful proptosis and nausea. Vision may be severely impaired. HISTORY AND SIGNS:A 77 years old lady woke up with sudden retroocular pain, diplopia and proptosis. Her blood pressure was 235 / 95 mmHg...

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    doi:10.1055/s-2008-1027354

    authors: Zuercher D,Tajouri N,van Issum C,Safran AB

    更新日期:2008-05-01 00:00:00

  • [Progressive enophthalmos in association with an orbital varix].

    abstract:BACKGROUND:The orbital varix is a rare congenital disorder. Men and women are equally affected. The disease becomes usually apparent during the third decade of life. PATIENT:A 66-year old women presented with a history of progressive enophthalmos for the last 45 years and complained of intermittent headache and visual...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:10.1055/s-2003-38631

    authors: Haritoglou C,Hintschich C

    更新日期:2003-04-01 00:00:00

  • [Complications after lid loading. Is the platinum chain really effective?].

    abstract:INTRODUCTION:Numerous studies on the operative therapy for lagophthalmos exist. Reports about postoperative results, however, are rare and most studies include just a small number of patients. Additionally, since 1999a flexible platinum chains has been available as an alternative to the rigid gold implant. The authors ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    doi:10.1055/s-2007-963790

    authors: Schrom T,Loch A,Habermann A,Knipping S

    更新日期:2008-02-01 00:00:00

  • [The modern body image as ethical device for biomedical enhancement].

    abstract::Ovid's "De medicamine faciei feminae" contains the astonishing sentence "Culta placent - all that is artificial is beautiful". In his "Éloge du maquillage" Baudelaire, buidling on Ovid's argument, states that first culture as picture and construction of beauty brings forth the truth of Nature and claims that cosmetics...

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    doi:10.1055/s-0032-1328108

    authors: Breitsameter C

    更新日期:2013-01-01 00:00:00

  • [Vibration, a new way of cutting in ophthalmic surgery (author's transl)].

    abstract::Rapid movement (vibration) of a movable scissor blade against a stationary blade at alternating current frequency (50 Hz) provides considerable improvement of cutting power and decreases distortion and crushing of the tissue. The article describes vibrational scissors for cataract surgery. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

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    authors: Spitznas M,Kreiger A

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  • Intravitreal triamcinolone injection for unresponsive cystoid macular oedema in probable Behçet's disease as an additional therapy.

    abstract:BACKGROUND:We present the description of a successful outcome of intravitreal triamcinolone injection (IVTA) in a patient with cystoid macular oedema (CME) and severe retinal vasculitis suggestive of ocular Behçet's disease. HISTORY AND SIGNS:A healthy 32 year-old Caucasian man presented initially with right retinal v...

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    authors: Oueghlani E,Pavésio CE

    更新日期:2008-05-01 00:00:00

  • [Membrane-bound carbonic anhydrase (CA IV) in human corneal epithelium and endothelium].

    abstract:PURPOSE:Active HCO3- transport through the corneal endothelial cell layer causes a dehydration of the corneal stroma and is thought to be driven by Na/K- and HCO3(-)-dependent ATPase as well as an electro-genic Na/HCO3- cotransport. Transmembrane bicarbonate transport has also been associated with the recently characte...

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    pub_type: 杂志文章

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    更新日期:1999-05-01 00:00:00

  • [Electroretinography changes in carriers of X-chromosomal retinitis pigmentosa].

    abstract::Out of five families with pedigrees typical for X-linked retinitis pigmentosa (RP) the authors examined eight definite and eight possible female carriers. Subjective symptoms were mild and variable, consisting mainly of relative nyctalopia. Ophthalmoscopic examination revealed a normal fundus, or mild changes suggesti...

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    doi:10.1055/s-2008-1050130

    authors: Brischnik E,Niemeyer G

    更新日期:1988-05-01 00:00:00

  • [Ocular manifestations of rheumatic diseases. Cooperation between internist/ophthalmologist].

    abstract::A red or painful eye may be the clue to a systemic condition, many of which are of a rheumatological or immunological nature. Conjunctivitis may occur in Sjögren's Syndrome, Reiter's Syndrome (and other sero negative spondyloarthropathies) and with infections such as chlamydia and viruses. 70% of cases of episcleritis...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1045602

    authors: Tyndall A,Steiger U

    更新日期:1993-05-01 00:00:00

  • [Iridocyclectomy with scleral flap].

    abstract::In this paper the author describes a modification of iridocyclectomy. Before opening the bulbus and removing the malignant melanoma, a lamellar scleral flap is formed with its base at the limbus. After extirpation of the tumor the area is "plastically" covered with this flap. This modification was used on 5 patients; ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Oláh Z

    更新日期:1983-12-01 00:00:00

  • [Metastatic carcinomata in the anterior uvea as the presenting clinical manifestation (author's transl)].

    abstract::Metastatic carcinomata in the anterior uvea are rare. Some of them may be diagnosed before the primary tumor is clinically detected. We report on three such cases. The vast majority of secondaries in the anterior uvea have their primary in the bronchus. It is rather exceptional that a metastasis in the anterior chambe...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1057611

    authors: Mellin KB

    更新日期:1980-07-01 00:00:00

  • [The cilia of the lacrimal sac epithelium SEM studies (author's transl)].

    abstract::On the basis of SEM studies it has been shown that the cilia are arranged into groups of 10 to 40 in the individual epithelial cells of the lacrimal sac. The cilia have a length of 15 to 20 micron. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Radnót M

    更新日期:1977-03-01 00:00:00

  • [Keratoconus and contact lenses (author's transl)].

    abstract::This work is a survey of 82 cases of keratoconus which have been followed up for 1 to 12 years. Among them only 66 were fitted with contact lenses. The contra-indications for them are: 1. a better visual acuity with spectacles than with contact lenses, 2. advanced cases (4th degree of Amsler) whose fitting is impossib...

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    pub_type: 杂志文章

    doi:

    authors: Massin M,Denis-Morère A,Ninine G

    更新日期:1976-01-01 00:00:00

  • [Abnormal head turn in a patient with Brown's syndrome].

    abstract:BACKGROUND:We report on an eight-year-old boy, who was presented in our clinic because of head turn. The cause of the tortecollis (ocular or general) in this case was and still cannot be explained. Only by applying extensive prism adaptation tests it was possible to prove the ocular character of the head turn. CASE RE...

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    authors: van Waveren M,Krzizok T,Besch D

    更新日期:2008-08-01 00:00:00

  • [Hereditary Optic Neuropathies].

    abstract::Hereditary optic nerve disorders are rare. For ophthalmologists, Leber's hereditary optic neuropathy (LHON) and autosomal dominant optic atrophy (ADOA) are of particular relevance. LHON and ADOA are diseases of the retinal ganglion cells and are caused by mitchochondrial dysfunction. LHON is based on mutations of the ...

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    pub_type: 杂志文章,评审

    doi:10.1055/a-0583-6290

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    更新日期:2018-06-01 00:00:00