[Survival after treatment for malignant choroidal melanoma: comparison between conservative therapy (Ru106/Rh106 applicator) and enucleation with and without postoperative irradiation to the orbit; 1960 to 1979].

Abstract:

:The survival rate was calculated using the life table method in 1,501 patients suffering from choroidal melanomas and treated in 10 eye hospitals in the GDR between 1960 and 1979. The results of treatment by (1) enucleation, (2) enucleation with postoperative irradiation of the orbit and (3) local irradiation with 106Ru/106Rh were compared. The 10-year survival rate in patients treated by 106Ru/106Rh irradiation (n = 187) was 72%; in a group of patients similar with regard to age, tumor size and cell type, but who had undergone enucleation (n = 241) the 10-year survival rate was 49%. This clearly indicates that irradiation of small melanomas with 106Ru/106Rh applicators (tumor base not larger than 10 mm, tumor height not more than 2 mm) produces the best therapeutic results. There was no statistically proven difference between survival rates in patients treated with enucleation and enucleation combined with postoperative irradiation of the orbit. Postoperative irradiation of the orbit does not improve the survival rate. The 10-year survival rate in patients aged up to 49 years was 83% after 106Ru/106Rh and 81% after enucleation; it was not possible to prove a difference statistically. The 10-year survival rate in patients aged between 50 and 69 years was 80% after 106Ru/106Rh (n = 93) and 46% after enucleation (n = 146). The superiority of local beta irradiation was statistically proven. The expected survival of people aged 70 years and over was affected neither by the choroidal melanoma nor by different therapeutic procedures.

journal_name

Klin Monbl Augenheilkd

authors

Kiehl H,Kirsch I,Lommatzsch P

doi

10.1055/s-2008-1054399

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

2-14

issue

1

eissn

0023-2165

issn

1439-3999

journal_volume

184

pub_type

杂志文章
  • "En face" OCT in Small Pigmented Choroidal Tumors.

    abstract::Background "En face" optical coherence tomography (OCT) is an imaging technique with optic sections parallel to the retinal pigment epithelium (RPE). This study aims to define the use of this technique in the evaluation of small pigmented choroidal tumors. Patients and Methods Investigation of 27 small pigmented choro...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0042-123172

    authors: Cotting-Bodmer S,Zografos L,Schalenbourg A

    更新日期:2017-04-01 00:00:00

  • [Minimally invasive lacrimal duct surgery with a multimodal concept for functional lacrimal stenosis].

    abstract:PURPOSE:The aim of this study was to evaluate the long-term success rates of a multimodal concept for treating functional nasolacrimal duct obstruction (FNLDO) consisting of minimally invasive lacrimal duct surgery and additional treatment of the conjunctiva, the puncta or the lids if necessary. METHODS:Clinical outco...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-0034-1383388

    authors: Stemplewitz B,Amin S,Emmerich KH,Gesser-Wendt C,Meyer-Rüsenberg HW

    更新日期:2015-01-01 00:00:00

  • [Long-term observation of ablatio-prophylaxis with kryopexy (author's transl)].

    abstract::Prophylactic cryo coagulation is especially suitable when there is cloudy media, e.g. blood in the vitreous body or a cataract which would prevent light or laser coagulation. Cryo lesions applied under ophthalmoscopic control are without complication. The paper reviews the 116 eyes collected in 1971 and augments it wi...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Kreissig I,Ruge I

    更新日期:1976-06-01 00:00:00

  • [Significance of the corneal thickness in non-contact tonometry].

    abstract::In this study the Reichert non-contact tonometer (NCT II) was compared with the Goldmann applanation tonometer (GAT) in 25 subjects (50 eyes; pressure range 9-17 mmHg). The relationship NCT/GAT fulfilled the conditions required for legal verification. Marked differences between the readings of both instruments can be ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046068

    authors: Gräf M

    更新日期:1991-09-01 00:00:00

  • [Refraction after cataract surgery with posterior chamber lenses].

    abstract::In an attempt to determine the accuracy of ultrasound biometry, the spherical equivalent of the refraction obtained after ECCE and implantation of a posterior chamber IOL in 1663 patients was compared to the desired refraction determined prior to surgery. Follow up time was 21 months on the average. In only 7.4% of th...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046055

    authors: Spitznas M,Werdermann D,Ohlhorst D

    更新日期:1991-08-01 00:00:00

  • [Correspondence alterations due to tenomyotomy (author's transl)].

    abstract::This report covers 310 patients with concomitant convergent strabismus and anomalous retinal correspondence. In 36 cases tenomyotomy alone was responsible for normalization of correspondence. This is best achieved in cases of bilateral converging strabismus without vertical divergence. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Schellenbeck R,Schmidt I

    更新日期:1979-08-01 00:00:00

  • [The learning curve in refractive laser surgery: criteria for outcome evaluation].

    abstract:BACKGROUND:We wanted to analyse and compare the results of our first 100 cases of refractive surgery using the commonly accepted refractive parameters and using more subjective data. MATERIALS AND METHODS:Retrospective analysis of the first 100 consecutive cases of refractive surgery using objective and subjective cri...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Artaria LG

    更新日期:1998-05-01 00:00:00

  • [Measurement of the diameter of segments of retinal branch vessels in digital fundus images - An experimental study of the method and reproducibility].

    abstract:PURPOSE:The aim of this study was the evaluation of new algorithms to measure diameter of segments of retinal branch vessels offline in local dependence and independent by observer. Methods 360 flashed fundus images (camera FF 450 ZEISS Germany, Visualis IMEDOS GmbH Weimar/Germany) of 12 eyes of healthy volunteers (10 ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2001-17640

    authors: Nagel E,Münch K,Vilser W

    更新日期:2001-09-01 00:00:00

  • [Nitrergic reactivity in endothelial cells of human uveal blood vessels].

    abstract:BACKGROUND:We investigated the presence of Nicotinamid-adenin-dinucleotid-phosphat (NADPH)-diaphorase activity in endothelial cells of the human uveal vessels, using a histochemical procedure which presumably localizes the reaction product nitric oxide. MATERIAL AND METHODS:11 donor eyes destined for corneal transplan...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035414

    authors: Bergua A

    更新日期:1995-02-01 00:00:00

  • [The results of surgical treatment of convergent strabismus (author's transl)].

    abstract::From the results of 628 operations on strabismus convergens, the individual corrections were related to the achieved reduction of the angle of deviation. The evaluation showed that strabismus operations may be well dosed not only with a view to a general improvement of the squint angle but also as a specific influence...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Kaufmann H,Sohlenkamp R,Hartwig H

    更新日期:1975-08-01 00:00:00

  • [Lowering of intraocular pressure by aqueous solution of bupranolol in chronic uncomplicated glaucoma simplex (author's transl)].

    abstract::In two previous studies the effects of topically applied 1% and 0.2% solutions of bupranolol on intraocular pressure were investigated in 21 and respectively 20 eyes with chronic uncomplicated open-angle glaucoma.--As early as 30 minutes after both solutions a very significant pressure drop, without concomittant pupil...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Oancea I,Trif V

    更新日期:1979-05-01 00:00:00

  • [Implant Design by Means of Multiphoton Polymerization].

    abstract:BACKGROUND:Additive manufacturing and 3D printing create new paths for the design and manufacturing of implants. Technologies with high resolution are required for the development of microstructured eye implants. In the present study, we demonstrate how these technologies can be used during the design development and m...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0041-107883

    authors: Hinze U,El-Tamer A,Reiß S,Stolz H,Guthoff R,Stachs O,Chichkov BN

    更新日期:2015-12-01 00:00:00

  • [History of the Berlin Ophthalmology Society].

    abstract::To mark the congress of the Berlin Ophthalmological Society in December 1989, the authors review the development of ophthalmology in Berlin and in particular the history of this ophthalmological society. The review was prompted by the political changes which began in October 1989, enabling ophthalmologists from the ea...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 历史文章,杂志文章

    doi:10.1055/s-2008-1045970

    authors: Goder GJ,Meinel U

    更新日期:1991-04-01 00:00:00

  • [Evaluation of Postoperative Astigmatism Correction and Postoperative Rotational Stability of Two Toric Intraocular Lenses].

    abstract::Background The aim of this retrospective study was to evaluate the rotational stability and the refractive outcome of two different toric IOLs. Methods This study included 41 eyes with corneal astigmatism greater than 1.5 diopters (D). All patients underwent surgery in the Department of Ophthalmology at Hietzing Hospi...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0043-100656

    authors: Grohlich M,Miháltz K,Lasta M,Weingessel B,Vécsei-Marlovits V

    更新日期:2017-06-01 00:00:00

  • [Clinical problems of different forms of heterochromie(author's transl)].

    abstract::The causes of hypo- and hyperchromic heterochromia were analysed in 94 patients. The hypochromic forms were the commonest, especially the Fuchs-Herrenschwandt heterochromia, and heterochromia simplex. Also after degenerative diseases and accidents appears almost exclusively hypochromic heterochromia. Causes of hyperch...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Pietruschka G,Priess G

    更新日期:1975-04-01 00:00:00

  • [Effect of nifedipine on ocular pulse amplitude in normal pressure glaucoma].

    abstract:BACKGROUND:Ocular pulse amplitude (OPA) is reduced in normal tension glaucoma (NTG) patients when compared to non-glaucomatous, healthy control subjects. This might be related to a vasospastic reaction. The objective of this study was to determine if low OPA in NTG is associated with a vasospastic reaction and its resp...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035074

    authors: Schmidt KG,von Rückmann A,Geyer O,Mittag TW

    更新日期:1997-06-01 00:00:00

  • [Impact of cataract surgery on intraocular pressure after filtering operation due to primary open angle glaucoma and secondary glaucoma in pseudoexfoliation syndrome].

    abstract:PURPOSE:To analyse the impact of cataract surgery after filtering operation on the intraocular pressure (IOP) due to primary open angle glaucoma (pOAG) versus secondary open angle glaucoma in pseudoexfoliation syndrome (PEX). The regulation of IOP was evaluated on the basis of criteria of advanced glaucoma intervention...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2002-26725

    authors: Wakili N,Seitz B,Hayler J,Händel A,Jünemann A

    更新日期:2002-03-01 00:00:00

  • [Real-time monitoring of a femtosecond laser in Sub-Bowman Keratomileusis on human donor eyes using OCT].

    abstract:PURPOSE:In LASIK (laser in situ keratomileusis) the thickness of the corneal flap is important since it is the residual corneal bed that determines corneal stability. The introduction of real-time OCT visualisation of the corneal layers during the fs-laser cut should enable the surgeon to control and monitor the positi...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0028-1109682

    authors: Kermani O,Oberheide U,Will GF,Massow O,Lubatschowski H

    更新日期:2009-12-01 00:00:00

  • [Treatment of retinal detachment with macular hole: scleral buckling with an absorbable fibrin sponge (author's transl)].

    abstract::In 21 patients with macular hole and retinal detachment a macular buckling procedure was performed including diathermic or cryogenic coagulation. An absorbable fibrin sponge (Fibrospum) was used as a new buckling material, which needs not to be sutured to the sclera at the posterior pole. In comparison to other proced...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Wollensak J,Engels T

    更新日期:1977-08-01 00:00:00

  • [Bitemporal hemianopia in road traffic].

    abstract:BACKGROUND:Patients suffering from pituitary adenomas and diseases of the chiasma typically show a bitemporal hemianopia. The residual undisturbed nasal visual fields of both eyes should have an extension of (at least) 120 degrees and are according to the actual German traffic rules (FeVAndV) for cars of the classes A,...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2006-926999

    authors: Krzizok T,Schwerdtfeger G

    更新日期:2006-09-01 00:00:00

  • [Initial results in percutaneous radiotherapy of malignant melanomas of the choroid with the linear accelerator].

    abstract::Twenty-seven eyes harboring a choroidal melanoma which could not be treated by other methods were treated with external beam radiation using a linear accelerator. After a mean follow-up period of 15.6 months 3 eyes had to be enucleated. In two eyes fresh tumors developed, which were successfully treated with local bet...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054595

    authors: Bornfeld N,Alberti W,Foerster MH,Gerke E,Wessing A,Meyer-Schwickerath G

    更新日期:1984-09-01 00:00:00

  • [Central areolar choroid dystrophy. Report of involvement of 3 generations].

    abstract::Central areolar chorodial atrophy was first classified as a hereditary disease by Sorsby in 1935. The mode of inheritance can be both autosomal recessive and autosomal dominant. The authors present a case with autosomal dominant inheritance affecting three generations. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046434

    authors: Hutter H,Marquardt R

    更新日期:1989-09-01 00:00:00

  • [Visual loss under silicone oil].

    abstract::Silicone oil is used as intravitreal tamponading agent in surgery for rhegmatogenous retinal detachment (RRD) cases complicated with proliferative vitreoretinopathy (PVR). Recently, a number of case series have appeared where profound central visual loss has been found in eyes after uncomplicated vitrectomy with silic...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0029-1245295

    authors: la Cour M,Lux A,Heegaard S

    更新日期:2010-03-01 00:00:00

  • [Malignant teratoid medulloepithelioma of the ciliary body and glial fibrillary acidic protein. Clinical, histochemical and immunohistochemical findings].

    abstract::In a four-year-old boy a malignant teratoid medulloepithelioma of the ciliary body was removed by means of an 11.0 X 11.0 mm "block excision". Two years later the patients visual acuity was 0.6. The lesion originates in the nonpigmented ciliary epithelium, extending along the lens equator to the pupillary zone and thr...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1051036

    authors: Holbach L,Völcker HE,Naumann GO

    更新日期:1985-10-01 00:00:00

  • [Structures of the European union--possibilities for influence by medical societies].

    abstract::In the EU more than 70 % of national law has already been replaced by EU law. Medical doctors are mostly not informed, how these EU-laws will pass. Many directives, regulations and decisions are important for medical doctors. A characterization of the EU- institutions is represented. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2005-858749

    authors: Grewe R

    更新日期:2005-11-01 00:00:00

  • [Blepharophimosis syndrome. Clinical aspects and therapy].

    abstract::Symptoms, genetics and differential diagnosis of this rare, congenital deformity of the lids are described. Strategies for the conservative and surgical therapy on the basis of own experiences and an extensive review of the literature are presented. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1035418

    authors: Hintschich CR,Zürcher M

    更新日期:1995-03-01 00:00:00

  • [Specifity of optic disc evaluation in healthy subjects with large optic discs and physiologic cupping using confocal scanning laser ophthalmoscopy].

    abstract:PURPOSE:Imaging methods of the optic nerve head appear to have an increasing impact in glaucoma diagnosis. The aim of this study is to evaluate the specifity of the Heidelberg Retina Tomograph (software version 1.7 and 3.0) in subjects with physiological cupping and large optic discs. PATIENTS AND METHODS:27 eyes of 2...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0032-1328094

    authors: Plange N,Hirsch T,Bienert M,Remky A

    更新日期:2014-02-01 00:00:00

  • [Lidloading and intraocular pressure].

    abstract:BACKGROUND:Implantation of rigid gold or platinum lid weights (lidloading) represents the most common method for therapy of patients with lagophthalmus as a result of facial palsy. In a more recent approach also flexible platinum chains have been used. Glaucoma has frequently been described as a contraindication for li...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2004-813940

    authors: Schrom T,Habermann A,Wernecke K,Scherer H,Duncker G

    更新日期:2005-01-01 00:00:00

  • [Clinical experience with iridencleisis].

    abstract::The authors report on 120 patients who underwent iridencleisis (155 eyes). Of these, 36 had open-angle glaucoma, 26 congestive glaucoma and 54 were suffering from acute glaucoma of long standing. Two patients had exfoliation syndrome and two, secondary glaucoma. The kind of filtration bleb, postoperative complications...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054765

    authors: Holland G,tho Seeth T

    更新日期:1983-04-01 00:00:00

  • [Blepharospasm treatment with botulinum toxin (follow-up)].

    abstract::Within a period of 14 months 73 patients with idiopathic blepharospasm which could not be treated satisfactorily by any other form of therapy were treated by injections of botulin toxin. In 55 cases the follow-up period was sufficiently long to permit an evaluation. Thirty-five patients were temporarily completely fre...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050804

    authors: Roggenkämper P

    更新日期:1986-10-01 00:00:00