Abstract:
BACKGROUND:Carbapenem-resistant Acinetobacter baumannii (CRAB) tops the list of threats to human health. Studies exploring predictors of mortality in patients with CRAB infection produced conflicting results. METHODS:A systematic search of the PubMed, Embase, and the Cochrane Library databases was performed from inception to June 2018 to identify studies reporting mortality predictors in patients infected with CRAB. Two authors independently assessed trials for inclusion and data extraction. RESULTS:A total of 19 observational studies were enrolled in this study. Factors associated with mortality of patients infected with CRAB were inappropriate empirical antimicrobial treatment (odds ratio [OR], 5.04; 95% confidence interval [CI], 2.56-9.94), septic shock (OR, 5.65; 95% CI, 2.35-13.57), chronic liver disease (OR, 2.36; 95% CI, 1.33-4.16), chronic renal disease (OR, 2.02; 95% CI, 1.37-2.99), hypertension (OR, 1.74; 95% CI, 1.08-2.80), neutropenia (OR, 3.31; 95% CI, 1.25-8.77), immunosuppressant use (OR, 3.15; 95% CI, 1.94-5.11), total parenteral nutrition (OR, 1.66; 95% CI, 1.08-2.56), and intubation (OR, 5.03; 95% CI, 2.33-10.87). Acute Physiology and Chronic Health Evaluation II score at admission and Pitt bacteremia score at the onset of CRAB bacteremia were higher in nonsurvivors. CONCLUSIONS:Our study suggests that severity of baseline condition and receiving inappropriate experience antibiotic therapy are major risk factors for higher mortality in patients with CRAB infections. These findings may help clinicians to take appropriate preventive measures and decrease mortality in such patients.
journal_name
Am J Infect Controljournal_title
American journal of infection controlauthors
Du X,Xu X,Yao J,Deng K,Chen S,Shen Z,Yang L,Feng Gdoi
10.1016/j.ajic.2019.03.003subject
Has Abstractpub_date
2019-09-01 00:00:00pages
1140-1145issue
9eissn
0196-6553issn
1527-3296pii
S0196-6553(19)30151-8journal_volume
47pub_type
杂志文章,meta分析abstract:BACKGROUND:This study examines how well regulations for bloodborne pathogens (BBPs), established primarily to reduce exposure risk for health care workers, are being followed by workers and employers in the tattooing and body piercing industry. METHOD:Twelve shops performing tattooing and/or body piercing (body art) i...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2009.07.008
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Influenza causes mortality and morbidity in the frail elderly population. Influenza prevention and mitigation models need to be developed for this population. METHODS:An observational study at a Program for All-Inclusive Care for the Elderly (PACE) during years 1999-2004. Participants were frail elderly adu...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2005.02.001
更新日期:2005-05-01 00:00:00
abstract::Our descriptive analyses show a wide distribution in rates of central line device days and central line-associated bloodstream infections for a given standardized infection ratio-the measure linked to federal payment penalties-among 215 US hospitals serving highly complex patient populations. We established that the s...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2018.12.001
更新日期:2019-08-01 00:00:00
abstract::Health care-associated infections impact patient morbidity and mortality, and institutions adopt evidence-based measures to prevent and control such infections. In this study, professionals were observed during patient care under empirical contact precautions. A total of 243 observations were performed in which 39.5% ...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2019.10.004
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Central line-associated bloodstream infection (CLABSI) is one of the most important health care-associated infections in the critical care setting. METHODS:A quasiexperimental study involving multiple interventions to reduce the incidence of CLABSI was conducted in a medical-surgical intensive care unit (IC...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2009.11.012
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Compliance with hand hygiene guidelines reduces the risk of health care-associated infection, yet doctors are less compliant than other health care workers. Use of observational hand hygiene auditing with targeted individualized feedback was implemented, with improved hand hygiene of consultant doctors; howe...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2018.12.024
更新日期:2019-07-01 00:00:00
abstract::To reduce surgical site infections (SSIs) in colorectal surgeries we introduced a bundle of care elements in partnership with the Enhanced Recovery after Surgery (ERAS) multidisciplinary team. We measured the incidence of National Healthcare Safety Network-defined SSIs, along with adherence to bundle care elements. De...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2018.11.004
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Horizontal transmission of bacteria, especially multidrug-resistant organisms (MDROs), remains an important concern in hospitals worldwide. Some studies have implicated provider attire in the transmission of organisms within hospitals, whereas others have suggested that evidence supporting this notion is lim...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2019.01.012
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:An outbreak of 5 inpatient and otherwise healthy children admitted for respiratory problems developed dry fever and cough after a few days of hospitalization. Burkhuldaria cepacia was isolated from their blood culture. The Infection Control Department (ICD) in the King Fahad Medical City (KFMC) detected and ...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2006.03.003
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:Most studies challenging the integrity of the glove barrier have compared the permeability of vinyl and latex gloves. However, no studies of a new nonlatex, nonvinyl thermoplastic elastomer have been reported. This pilot study therefore compared the protective barriers provided by latex and thermoplastic ela...
journal_title:American journal of infection control
pub_type: 杂志文章,评审
doi:10.1016/0196-6553(93)90385-h
更新日期:1993-12-01 00:00:00
abstract::Urinary tract infections are one of the most common hospital-acquired infections, with 70%-80% resulting from catheter-associated urinary tract infections (CAUTIs). We undertook a qualitative study to assess patient perspectives of indwelling urinary catheters using a semistructured interview. We found that patient aw...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2015.10.011
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Hospital-acquired infection, including catheter-associated urinary tract infection (CAUTI), is common. Although CAUTI is usually preventable, hospital units may struggle to reduce CAUTI rates. The CAUTI guide to patient safety (GPS) was developed to assess a unit's CAUTI prevention activities. Our aim was to...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2016.03.051
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:The guideline for staffing infection control programs of 1 infection control professional (ICP) for every 250 occupied acute care beds has been used in many health care facilities in the United States since 1985. Since that time, the health care system, patient populations, and expectations about the work of...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1067/mic.2002.127930
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Control of infection within the long-term care facility is a daunting problem. Elderly patients are at high risk for contracting infection because of reduced innate immunity, malnutrition, and the presence of chronic medical conditions. This small study tested the effect of developing and implementing a comp...
journal_title:American journal of infection control
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0196-6553(00)90004-x
更新日期:2000-02-01 00:00:00
abstract::To describe the characteristics of needlestick injuries occurring to health care workers outside the hospital, a new case report form was implemented and analyzed after 12 months. A total of 144 incidents were reported. Of the needlestick injuries in nursing assistants, 84% involved an insulin needle or pen. Thirty-fi...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2006.02.004
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Isolation precautions used against multidrug-resistant (MDR) organisms are responsible for many emotional side effects. We evaluated patient's feeling after a hospitalization for an MDR infection. METHODS:We conducted a qualitative study that included 11 interviews from August 2017 to June 2018. We used phe...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2019.03.018
更新日期:2019-09-01 00:00:00
abstract::The primary job responsibility of infection preventionists (IPs) is to lead organizational initiatives that prevent and control health care-associated infections. Increasingly, IPs are participating in activities that support antimicrobial stewardship programs (ASPs). We conducted a survey of Association of Profession...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2020.02.003
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Manual cleaning of flexible endoscopes is prone to error. To date, attempts to automate this process have been unsuccessful. The aim of this project was to compare the efficacy of the washing phase in the new Reliance EPS (STERIS Corp, Mentor, OH) with that of optimal manual cleaning. METHODS:Using simulate...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2006.01.010
更新日期:2006-11-01 00:00:00
abstract::In this study examining public health workers' 2009 H1N1 and seasonal influenza vaccination uptake, a survey was conducted to assess flu vaccine acceptance, as well as behaviors and beliefs regarding acceptance, among public health workers in southeastern Tennessee. Factors found to be significantly associated with ac...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2011.05.010
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Antibiotic resistance is a challenge in long-term care facilities (LTCFs). The objective of this study was to demonstrate that a novel, minimally invasive program not interfering with activities of daily living or socialization could lower methicillin-resistant Staphylococcus aureus (MRSA) disease. METHODS:...
journal_title:American journal of infection control
pub_type: 临床试验,杂志文章
doi:10.1016/j.ajic.2016.04.251
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:The purpose of this quality improvement project was to determine the effect of providing feedback to managers and bedside nurses on the nurses' central line-associated bloodstream infection (CLABSI) contributing factors, found on visual and documentation audits. METHODS:This nonexperimental, quality improve...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2016.09.020
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The role of the infection preventionist (IP) has become increasingly complex, underscoring the need for rapid mechanisms of knowledge acquisition. One mechanism for knowledge acquisition is knowledge-sharing through social networks. In a state such as Kentucky with predominantly rural health care facilities,...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2011.05.018
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:ICD-9-CM coding alone has been proposed as a method of surveillance for health care-associated infections (HAIs). The accuracy of this method, however, relative to accepted infection control criteria is not known. METHODS:Retrospective analysis of patients at an academic medical center in 2005 who underwent...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2008.01.004
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:This report summarizes the scope and role of infection preventionists in emergency management for all types of disasters. Preventing the transmission of infectious agents during a disaster is an essential component of emergency management. Previous disasters have illustrated the need for better infection pre...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2008.12.002
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Needleless connectors (NCs) were introduced to reduce health care work needlestick injuries (NSIs). If not decontaminated prior to use, NCs can be a portal for patient blood stream infections. The optimal disinfectant, and its application duration, for NC decontamination has not been empirically established....
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2019.11.030
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Anesthesia providers are at risk for contracting COVID-19 due to close patient contact, especially during shortages of personal protective equipment. We present an easy to follow and detailed protocol for producing 3D printed face shields and an effective decontamination protocol, allowing their reuse. METH...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2020.07.037
更新日期:2020-08-04 00:00:00
abstract:BACKGROUND:Comparability of the 2 commercially available tuberculin skin testing (TST) preparations, Aplisol (Parkdale Pharmaceuticals, Inc, Rochester, MI) and Tubersol (Aventis Pasteur, Inc, Swiftwater, PA), remains uncertain, particularly in groups that undergo repeated testing, such as health care workers. METHODS:...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2006.05.288
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:The number and significance of tuberculin skin test reactions were compared with self-reported baseline values among house staff working in a public hospital. High-risk medical specialties, locations, and infection control practices were examined. METHODS:House staff interviews, tuberculin skin test applica...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/s0196-6553(96)90047-4
更新日期:1996-02-01 00:00:00
abstract::The overall risk of infection from medical devices is very low, but high infection transmission rates have been related to inadequate reprocessing of arthroscopic shavers and flexible duodenoscopes. Monitoring of manual and automated cleaning is needed to ensure that inadequately cleaned medical devices are recleaned ...
journal_title:American journal of infection control
pub_type: 杂志文章,评审
doi:10.1016/j.ajic.2012.12.006
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Catheter-associated urinary tract infection is the most common health care-associated infection, is considered avoidable, and has cost implications for health services. Prevalence is high in nursing homes, but little research has been undertaken to establish whether implementing clinical guidelines can reduc...
journal_title:American journal of infection control
pub_type: 杂志文章,评审
doi:10.1016/j.ajic.2016.09.015
更新日期:2017-05-01 00:00:00