Abstract:
BACKGROUND:Needleless connectors (NCs) were introduced to reduce health care work needlestick injuries (NSIs). If not decontaminated prior to use, NCs can be a portal for patient blood stream infections. The optimal disinfectant, and its application duration, for NC decontamination has not been empirically established. METHODS:Factorial design randomized controlled trial comparing 70% isopropyl alcohol (IPA) and 2% chlorhexidine gluconate (CHG) in 70% IPA for 5, 10, or 15 seconds, in adult medical patients with peripheral intravenous catheters. RESULTS:At baseline, 153 of 300 NCs (51%) grew microorganisms commonly found on the skin. Decontamination was successful in 150/153 (98%). There was no significant difference in decontamination between 70% IPA or 2% CHG in 70% IPA (P = .62), or decontamination for 5, 10, or 15 seconds (P = .21). CONCLUSIONS:There was no difference in the effectiveness of 70% IPA and 2% CHG in 70% IPA for NC decontamination for peripheral intravenous catheters in the clinical environment. Successful decontamination was not different for applications of 5, 10, and 15 seconds; 15 seconds did not always remove all microorganisms. Factors such as cost, feasibility of compliance, and low risk of allergy support 5 seconds decontamination with 70% IPA as an acceptable approach.
journal_name
Am J Infect Controljournal_title
American journal of infection controlauthors
Slater K,Cooke M,Fullerton F,Whitby M,Hay J,Lingard S,Douglas J,Rickard CMdoi
10.1016/j.ajic.2019.11.030subject
Has Abstractpub_date
2020-09-01 00:00:00pages
1013-1018issue
9eissn
0196-6553issn
1527-3296pii
S0196-6553(19)31017-Xjournal_volume
48pub_type
杂志文章abstract::The purpose of this study was to conduct a nationwide survey to determine the number of master's-prepared infection control practitioners (ICPs) and those eligible for admission to graduate programs. Continuing education needs also were assessed to determine whether they might best be met through formal education or i...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/0196-6553(90)90087-9
更新日期:1990-04-01 00:00:00
abstract::A survey of purchasers of The APIC Curriculum for Infection Control Practice was conducted in early 1985 by the APIC Curriculum Committee to determine characteristics of purchasers, usability of the text, reasons for purchase, and availability of references cited. Data were obtained from 342 (54.3%) respondents to a n...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/0196-6553(85)90025-2
更新日期:1985-12-01 00:00:00
abstract:BACKGROUND:Despite increased focus on health care-associated infections (HAI), between 1.6 and 3.8 million HAI occur annually among the vulnerable population residing in US nursing homes (NH). This study characterized state department of health (DOH) activities and policies intended to improve quality and reduce HAI in...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2013.11.024
更新日期:2014-04-01 00:00:00
abstract::We tested the ability of an improved hydrogen peroxide solution to decontaminate privacy curtains in inpatient and outpatient areas. The microbial contamination of the curtains was assessed before and after the curtains were sprayed with improved hydrogen peroxide. The disinfectant reduced the microbial load on the pr...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2013.11.022
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Hand cleanliness is important in hospital infection control, but skin irritation from frequent alcohol-based hand rub use reduces compliance. We have compared a new copper biocide/Aloe vera-based biocidal hand rub (Xgel) with 7 commercially available hand rubs. METHODS:Hand rubs were cultured with human ski...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2008.09.011
更新日期:2009-05-01 00:00:00
abstract::Over the last decade, substantial scientific evidence has accumulated that indicates contamination of environmental surfaces in hospital rooms plays an important role in the transmission of key health care-associated pathogens (eg, methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, Clostrid...
journal_title:American journal of infection control
pub_type: 杂志文章,评审
doi:10.1016/j.ajic.2015.11.015
更新日期:2016-05-02 00:00:00
abstract::Oral care is an important component of the ventilator bundle; however, few studies have investigated the factors related to compliance with performing oral care among critical care nurses. In this observational study of 759 oral care opportunities performed by 133 critical care nurses, we found that the overall oral c...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2014.01.023
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Bacillus cereus can cause severe infections in immunocompromised persons. METHODS:We report 3 cases of bacteremia/septicemia (1 fatal) among oncology patients in a children's hospital. Because all cases occurred during a 10-day period, a common source outbreak was suspected. An epidemiologic investigation w...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/s0196-6553(99)70034-9
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:Previous studies have drawn different conclusions about the impact of Candida airway colonization on clinical outcomes in patients with ventilator-associated pneumonia (VAP). METHODS:We searched PubMed, the Cochrane Library, Embase (via OVID), and Web of Science database. We included both retrospective and ...
journal_title:American journal of infection control
pub_type: 杂志文章,评审
doi:10.1016/j.ajic.2019.11.002
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Patient hand hygiene may be a useful strategy to prevent acquisition of pathogens and to reduce the risk for transmission by colonized patients. Several studies demonstrate that patients and long-term-care facility (LTCF) residents may have difficulty using hand hygiene products that are provided; however, n...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2016.12.023
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Catheter-associated urinary tract infection is the most common health care-associated infection, is considered avoidable, and has cost implications for health services. Prevalence is high in nursing homes, but little research has been undertaken to establish whether implementing clinical guidelines can reduc...
journal_title:American journal of infection control
pub_type: 杂志文章,评审
doi:10.1016/j.ajic.2016.09.015
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Healthcare-associated infections (HAIs) are common and often preventable complications of care, with reduction emphasized in national policy. The Centers for Medicare and Medicaid Services introduced an HAI-focused Hospital Acquired Condition Reduction Program in 2015 to penalize poor-performin...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2020.05.038
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) infections are a concern across the worldwide. METHODS:Antibiotic stewardship and hand hygiene programs were reinforced in a 2,000-bed tertiary hospital in South Korea where the methicillin resistance rate of Staphylococcus aureus is about 65%. The computer...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2012.12.018
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Infection control practice compliance is commonly monitored by measuring hand hygiene compliance. The limitations of this approach were recognized in 1 acute health care organization that led to the development of an Infection Control Continuous Quality Improvement tool. METHODS:The Pronovost cycle, Barrier...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2019.06.014
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Outbreaks of health care-associated infections in neonatal intensive care units (NICUs) are frequent and have received more attention in medical literature than outbreaks from other types of intensive care units (ICUs). The objective of this systematic review was to identify differences between outbreaks of ...
journal_title:American journal of infection control
pub_type: 杂志文章,评审
doi:10.1016/j.ajic.2006.07.007
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND:Health care-associated infection is one of the most important patient safety problems in the world. While many methods exist to prevent health care-associated infection, most experts believe that improving hand hygiene is paramount. We previously published the results of a successful before-and-after hand hy...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2010.06.015
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Ventilator-associated pneumonia (VAP) is a nosocomial pneumonia that develops in patients on mechanical ventilation for >or=48 hours. VAP develops at an estimated rate of 1% to 3% per day of mechanical ventilation. METHODS:Quality improvement project. Mechanically ventilated patients received the following ...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2008.12.007
更新日期:2009-09-01 00:00:00
abstract::Infection control professionals have traditionally relied on didacticism to promote behavior change among health care workers, but this approach yields disappointing results in a postmodern era of social fragmentation and intellectual ambiguity. We define a socioethical approach to behavior change and propose its impl...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2005.09.004
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Community-based points of dispensing (POD) will be used during disasters to distribute mass quantities of anti-infective therapy/prophylaxis and/or vaccination to an entire community in a short period of time. Without proper planning, staff training, and implementation of infection prevention strategies, dis...
journal_title:American journal of infection control
pub_type: 杂志文章,评审
doi:10.1016/j.ajic.2009.09.001
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:Thermally injured patients are at high risk for infections, including hospital acquired infections (HAIs). We modeled a twice-daily chlorhexidine gluconate (CHG) bath protocol aimed at decreasing HAIs. METHODS:Bathing with a 0.9% CHG solution in sterile water was provided twice daily as part of routine care...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2013.08.015
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:This study assessed reporting behavior and satisfaction with postexposure prophylaxis (PEP) systems among health care workers (HCWs) at risk for occupational bloodborne pathogen exposure (BPE) in 3 public hospitals in Botswana. METHODS:A cross-sectional survey among HCWs provided information on perceptions,...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2016.01.027
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Annual influenza vaccination is recommended for all persons aged ≥6 months. The objective of this study was to assess trends in racial/ethnic disparities in influenza vaccination coverage among adults in the United States. METHODS:We analyzed data from the 2007-2012 National Health Interview Survey (NHIS) a...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2014.03.021
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:This report summarizes the scope and role of infection preventionists in emergency management for all types of disasters. Preventing the transmission of infectious agents during a disaster is an essential component of emergency management. Previous disasters have illustrated the need for better infection pre...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2008.12.002
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) strains were isolated and characterized from environmental surfaces of two fire stations from two independent districts in the northwestern United States. After the first sampling and before the second sampling, education was provided, additional signage was...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2010.09.008
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Health care personnel (HCP) working while experiencing influenza-like illness (ILI) contribute to influenza transmission in health care settings. Studies focused on certain HCP occupations or work settings have demonstrated that some HCP often continue to work while ill. METHODS:Using a national nonprobabil...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2017.04.008
更新日期:2017-11-01 00:00:00
abstract::Several authors have proposed the use of statistical process control charting methods for the surveillance of endemic rates of nosocomial infections. The principal goal of such a charting program is to recognize any increase of the endemic rate to an epidemic rate as soon as possible after the change occurs. However, ...
journal_title:American journal of infection control
pub_type: 杂志文章,评审
doi:10.1067/mic.2000.106277
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:The potential risks associated with "toilet plume" aerosols produced by flush toilets is a subject of continuing study. This review examines the evidence regarding toilet plume bioaerosol generation and infectious disease transmission. METHODS:The peer-reviewed scientific literature was searched to identify...
journal_title:American journal of infection control
pub_type: 杂志文章,评审
doi:10.1016/j.ajic.2012.04.330
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Aerobic and facultatively anaerobic gram-negative bacilli (AGNB) are opportunistic pathogens and continue to cause a large number of hospital-acquired infections. AGNB residing in the oral cavity and oropharynx have been linked to nosocomial pneumonia and septicemia. Although AGNB are not considered members ...
journal_title:American journal of infection control
pub_type: 杂志文章,评审
doi:10.1016/j.ajic.2011.03.004
更新日期:2012-03-01 00:00:00
abstract::The primary job responsibility of infection preventionists (IPs) is to lead organizational initiatives that prevent and control health care-associated infections. Increasingly, IPs are participating in activities that support antimicrobial stewardship programs (ASPs). We conducted a survey of Association of Profession...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2020.02.003
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Colonized or infected patients are a major reservoir for patient-to-patient transmission of methicillin-resistant Staphylococcus aureus (MRSA) in hospitals. Despite attempted adherence to recommended infection prevention and control procedures, a general medicine unit in our hospital continued to experience ...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2008.05.007
更新日期:2009-03-01 00:00:00