Abstract:
BACKGROUND:Central line-associated bloodstream infection (CLABSI) is one of the most important health care-associated infections in the critical care setting. METHODS:A quasiexperimental study involving multiple interventions to reduce the incidence of CLABSI was conducted in a medical-surgical intensive care unit (ICU) and in 2 step-down units (SDUs). From March 2005 to March 2007 (phase 1 [P1]), some Centers for Disease Control and Prevention evidence-based practices were implemented. From April 2007 to April 2009 (P2), we intervened in these processes at the same time that performance monitoring was occurring at the bedside, and we implemented the Institute for Healthcare Improvement central line bundle for all ICU and SDU patients requiring central venous lines. RESULTS:The mean incidence density of CLABSI per 1000 catheter-days in the ICU was 6.4 in phase 1 and 3.2 in phase 2, P < .001. The mean incidence density of CLABSI per 1000 catheter-days in the SDUs was 4.1 in phase 1 and 1.6 in phase 2, P = .005. CONCLUSION:These results suggest that reducing CLABSI rates in an ICU setting is a complex process that involves multiple performance measures and interventions that can also be applied to SDU settings.
journal_name
Am J Infect Controljournal_title
American journal of infection controlauthors
Marra AR,Cal RG,Durão MS,Correa L,Guastelli LR,Moura DF Jr,Edmond MB,Dos Santos OFdoi
10.1016/j.ajic.2009.11.012subject
Has Abstractpub_date
2010-08-01 00:00:00pages
434-9issue
6eissn
0196-6553issn
1527-3296pii
S0196-6553(10)00069-6journal_volume
38pub_type
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