Aspergillus vegetative endocarditis complicated with schizocytic hemolytic anemia in a patient with acute lymphocytic leukemia.

abstract：:A 59-year-old man presented with lymphocytosis with huge splenomegaly. The abnormal lymphocytes had a high nucleoplasm:cytoplasm ratio, a prominent nucleolus and hairy cytoplasmic projections. Immunophenotyping revealed B-cell leukemia with negative reactions to CD5 and CD25. Cytogenetic study showed 46,XY,der(5)t(5;6...

journal_title：Acta haematologica

authors： Dunn P,Shih LY,Ho YS,Tien HF

更新日期：1995-01-01 00:00:00

abstract：:The plasma cortisol levels of 108 children aged 1-16 years with various Hb genotypes (AA, AS and SS) were measured. The mean plasma cortisol levels of both the AS and SS groups (during steady state) fell within the normal range but the mean of the SS group is significantly lower than the AA group. In fact, 9 of the si...

journal_title：Acta haematologica

authors： Osifo BO,Lukanmbi FA,Adekile A

更新日期：1988-01-01 00:00:00

abstract：:A rare case of acute promyelcytic leukemia (APL) is reported in a 7-year-old boy. The patient displayed the typical features of APL including impaction of the marrow with promyelocytes, marked elevation of the serum vitamin B12 and transcobalamin I levels and a hemorrhagic diathesis. The bleeding diathesis in the case...

journal_title：Acta haematologica

authors： Engelhard D,Yatziv S,Rachmilewitz EA,Polliack A

更新日期：1979-01-01 00:00:00

abstract：:A case of isolated lambda-light chain proteinemia and proteinuria is reported. During a 42-month follow-up, no sign of myelomatosis or amyloidosis developed and Bence Jones proteinuria remained nearly of the same magnitude. This case of apparently idiopathic Bence Jones gammopathy, the first lambda-type so far reporte...

journal_title：Acta haematologica

authors： Paladini G,Sala PG,Santini PA

更新日期：1980-01-01 00:00:00

abstract：:Peripheral blood stem cells (PBSC) are widely used in the setting of dose-intensive chemotherapies in patients with multiple myeloma (MM). Although the granulocyte colony-stimulating factor (G-CSF), following chemotherapy or not, is considered the standard growth factor for mobilizing PBSC, the optimal chemotherapeuti...

journal_title：Acta haematologica

authors： Petrucci MT,Avvisati G,La Verde G,De Fabritiis P,Ribersani M,Palumbo G,De Felice L,Rusignuolo A,Simone F,Meloni G,Mandelli F

更新日期：2003-01-01 00:00:00

abstract：:von Willebrand disease (VWD) type 2M is a distinct entity and clearly differs from type 1. The genotype-phenotype correlation for cases with ristocetin cofactor activity (RCo)/antigen (Ag) ratios <0.60 is clear, whereas the von Willebrand factor (VWF):collagen binding (CB)/VWF:Ag ratio is normal in VWD 2M. Typical lab...

journal_title：Acta haematologica

authors： Hermans C,Batlle J

更新日期：2009-01-01 00:00:00

abstract：:Plasma samples from patients with disseminated intravascular coagulation (DIC) associated with acute promyelocytic leukemia (APL) exhibited higher levels of the D-fragment of fibrin and fibrinogen degradation products [FDP(D)], with relatively lower levels of cross-linked fibrin degradation products (XDP), than sample...

journal_title：Acta haematologica

authors： Okajima K,Koga S,Okabe H,Inoue M,Takatsuki K

更新日期：1989-01-01 00:00:00

abstract：:The unstable haemoglobin, Tb Torino (alpha43(CD1)Phe replaced by Val), has been found for the second time in a family from the Treviso region of Italy. The haemoglobin has a slightly lower oxygen affinity than normal. In both cases, the abnormal haemoglobin is associated with inclusion body anaemia but the course of t...

journal_title：Acta haematologica

authors： Sansone G,Sciarratta GV,Lang A,Lorkin PA,Lehmann H

更新日期：1976-01-01 00:00:00

abstract：:10 patients with paroxysmal nocturnal hemoglobinuria were studied taking 109 normal subjects of the Cuban population as control group. 26 HLA antigens corresponding to loci A and B were studied in both groups. Phenotypical frequency of both groups were compared. No statistically significant increase was found for any ...

journal_title：Acta haematologica

authors： Ustariz CR,Arce S,Hernández P,Almaguer M,Pérez S,Ballester JM

更新日期：1980-01-01 00:00:00

abstract：:Downregulation of apoptosis has been proposed as a mechanism of clonal expansion in low-grade B cell neoplasms. We have previously described an unusual case of CD5+ B cell lymphoma characterized by cycles of leukemic phase alternating with spontaneous remission. In the present study, we examined the involvement of apo...

journal_title：Acta haematologica

authors： Aizman I,Many A,Peller S,Ramot B,Kaufmann Y

更新日期：2000-01-01 00:00:00

abstract：:Premature neonates require blood transfusions, and biological parents may wish to be directed donors. Biological mothers pose a potential danger because their plasma may contain antibodies that will react with blood cell antigens inherited by the infant from the father. We studied 25 healthy, pregnant women at the tim...

journal_title：Acta haematologica

authors： Elbert C,Strauss RG,Barrett F,Goeken NE,Pittner B,Cordle D

更新日期：1991-01-01 00:00:00

abstract：:The value of clearance of peripheral blood blasts (PBB) as a predictor of outcomes in acute myeloid leukemia (AML) is controversial. To investigate the prognostic significance of the time to clearance of PBB after induction in Chinese patients with AML, a retrospective analysis of 146 patients with newly diagnosed AML...

journal_title：Acta haematologica

authors： Li X,Zhu H,Zhang Y,Zhao W,Mi J,Hu J,Li J

更新日期：2016-01-01 00:00:00

abstract：:Bone marrow samples of 28 individuals with clinically benign and of 41 patients with malignant monoclonal gammopathy were analyzed for the total number of lymphoplasmocellular elements containing cytoplasmic immunoglobulins and for the monoclonal fraction of these cells. Monoclonal immunoglobulin components were deter...

journal_title：Acta haematologica

authors： Morell A,Maurer W,Skvaril F,Barandun S

更新日期：1978-01-01 00:00:00

abstract：:At our hospital, 47 out of 184 consecutive splenectomies performed over 7 recent years were carried out on patients afflicted with various hematologic diseases. The results of these 47 splenectomies were the subject of a careful retrospective analysis. The majority of the splenectomies (81%) were therapeutic. Cytopeni...

journal_title：Acta haematologica

authors： Dotevall A,Kutti J,Wadenvik H,Westin J,Angerås U,Darle N

更新日期：1987-01-01 00:00:00

abstract：:Fetal liver transplantation was attempted in 7 patients with aplastic anemia. 4 of these patients showed a partial response as evidenced by decrease in blood transfusion requirements and increase in the peripheral blood counts and hematopoietic cells in the bone marrow. Bone marrow culture studies revealed evidence of...

journal_title：Acta haematologica

authors： Kansal V,Sood SK,Batra AK,Adhar G,Malviya AK,Kucheria K,Balakrishnan K

更新日期：1979-01-01 00:00:00

abstract：:In a previous study, we evaluated efficacy of repeated antilymphocyte globulin (ALG) treatment for patients with severe aplastic anemia not responding to an initial ALG treatment or relapsing after initial response to ALG. We now searched in the same cohort of patients for differences between patients who responded to...

journal_title：Acta haematologica

authors： Viollier R,Tichelli A

更新日期：2000-01-01 00:00:00

abstract：:The effect of 3 different detergents (Triton X-100, Lubrol WX and Nonidet) on brain thromboplastin was examined and compared with the solubilisation due to deoxycholate. The effect of deoxycholate is superior over that of the other examined detergents. Deoxycholate extracts thromboplastic activity from brain tissue to...

journal_title：Acta haematologica

authors： Bayer PM,Deutsch E

更新日期：1975-01-01 00:00:00

abstract：:Systematic reviews and meta-analyses have made a major contribution to the evidence-based management of infections in cancer patients. We review the contribution of systematic reviews with regard to antibiotic, antifungal, antiviral and Pneumocystis pneumonia prophylaxis; antibiotic and antifungal treatment of febrile...

journal_title：Acta haematologica

authors： Paul M,Gafter-Gvili A,Goldberg E,Yahav D

更新日期：2011-01-01 00:00:00

abstract：:Afibrinogenaemia in a female Saudi child is reported. Two siblings died of bleeding. The parents, who are first cousins, a brother and two sisters are asymptomatic heterozygotes with fibrinogen levels of less than 1.5 g/l. The presentation was described and compared to other cases reported. ...

journal_title：Acta haematologica

authors： Elseed FA,Karrar ZA

更新日期：1984-01-01 00:00:00

abstract：:Pyruvate kinase (PK) from four patients with moderate to severe congenital non-spherocytic haemolytic anaemia was characterized by methods recommended by the ICSH. The possibility that two of the patients are true homozygotes cannot be ruled out, while the other two apparently represent double heterozygotes. All but o...

journal_title：Acta haematologica

authors： Tegos C,Anagnostoulis G

更新日期：1994-01-01 00:00:00

abstract：:A subpopulation with alkaline phosphatase activity and neutrophilic granules was found in leukemic monocytes from a child with acute monocytic leukemia (M5B). Almost all leukemic cells were strongly positive for nonspecific esterase and phagocytized opsonized zymosans. These findings suggest that the subpopulation are...

journal_title：Acta haematologica

authors： Tomonaga M,Ichimaru M,Tsuji Y

更新日期：1984-01-01 00:00:00

abstract：:RAS mutations are found in about 25% of acute myeloid leukemia (AML) cases. The importance of these changes is unknown. If RAS mutations confer growth advantage to leukemia subclones in which they emerge, substantially more nonconservative than conservative mutations should be found. The incidence of conservative muta...

journal_title：Acta haematologica

authors： Aurer I,Labar B,Nemet D,Ajduković R,Bogdanić V,Gale RP

更新日期：1994-01-01 00:00:00

abstract：:Acute myelogenous leukemia (AML) of the inbred Wistar/Furth (W/Fu) rat is pathophysiologically similar to human AML. Subcutaneous transplantation of 1.0 X 10(6) cells of a clonal tissue culture line of W/Fu AML into 6- to 8-week-old rats produced local myeloblastomas in 8--10 days which progressed to infiltration of r...

journal_title：Acta haematologica

authors： Greenberger JS,Bocaccino CA,Szot SJ,Moloney WC

更新日期：1977-03-01 00:00:00

abstract：:We have been studying hematopoietic effects by the tachykinins, which like many other neuropeptides can be expressed in neural and nonneural tissues. Substance P (SP) and neurokinin-A (NK-A), members of the tachykinins are immune and hematopoietic modulators. SP and NK-A are derived from the preprotachykinin-I gene (P...

journal_title：Acta haematologica

authors： Rameshwar P,Gascón P

更新日期：1997-01-01 00:00:00

abstract：:A family with hereditary ovalocytosis (HO) is described. The probands, 2 brothers, had splenic rupture after modest trauma as preenting symptoms. 7 members of the family had HO. The sister of the pobands had a moderately enlarged spleen. The other members proved normal on routine clinical examination. ...

journal_title：Acta haematologica

authors： Kjellman B,Larsson C,Tibblin E

更新日期：1980-01-01 00:00:00

abstract：:Essential thrombocythemia (ET), one of the chronic myeloproliferative disorders, is a clonal disorder of multipotent stem cells. Although most patients with ET have a prolonged benign course, a minority of patients may develop a blastic crisis similar to chronic myelogenous leukemia (CML). A case of ET terminating in ...

journal_title：Acta haematologica

authors： Shibata K,Shimamoto Y,Suga K,Sano M,Matsuzaki M,Yamaguchi M

更新日期：1994-01-01 00:00:00

abstract：:A patient with regional enteritis had received iron dextran for treatment of iron deficiency. Subsequently he developed a large (3.1 g/100 ml) IgG-K serum spike which had precipitin activity against dextran sulfate but not a variety of other antigens. There has been no evidence of multiple myeloma and the spike gradua...

journal_title：Acta haematologica

authors： Shimm DS,Cohen HJ

更新日期：1978-01-01 00:00:00

abstract：:Thrombopoietin levels in thrombocytopenic mice assayed by 75Se-se-lenomethionine incorporation into blood platelets reached a maximum 12 h after the induction of an acute, immune thrombocytopenia; that was more than twice the value in control mice. The implications of this finding are discussed with reference to the k...

journal_title：Acta haematologica

authors： Nakeff A,Roozendaal KJ

更新日期：1975-01-01 00:00:00

abstract：:A diester lipase activity is described in human red blood cells (RBC). Diester lipase activity acts as a membrane-bound enzyme and is assayed using intact RBC as the enzyme source. An emulsion of di-[3H]-oleoylglycerol (0.6 mM) serves as the substrate. The optimum pH for the reaction is 7.8 at 37 degrees C. Lipolytic ...

journal_title：Acta haematologica

authors： Somma C,Arnaud J,Boyer J

更新日期：1983-01-01 00:00:00

abstract：:Janus kinases are critical components of signaling pathways that regulate hematopoiesis. Mutations of the non-receptor tyrosine kinase JAK2 are found in many BCR-ABL-negative myeloproliferative neoplasms. Preclinical results support that JAK2 inhibitors could show efficacy in treating chronic myeloproliferative neopla...

journal_title：Acta haematologica

authors： Ringel F,Kaeda J,Schwarz M,Oberender C,Grille P,Dörken B,Marque F,Manley PW,Radimerski T,le Coutre P

更新日期：2014-01-01 00:00:00