Practical considerations in the development and refinement of subcallosal cingulate white matter deep brain stimulation for treatment-resistant depression.

Abstract:

BACKGROUND:Deep brain stimulation has been investigated in the past decade as a viable intervention for treatment-resistant depression. METHODS:Several anatomic targets have been tested, with the most extensive published experience found for the subcallosal cingulate (SCC) white matter. RESULTS:This article reviews the current state of clinical research of SCC deep brain stimulation for treatment-resistant depression, including an overview of the rationale for targeting SCC, practical considerations for subject recruitment and evaluation, surgical planning, and stimulation parameters. CONCLUSION:Clinical management of patients in the initial and long-term naturalistic phases of treatment, including the potential role for psychotherapeutic rehabilitation, is discussed.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Riva-Posse P,Holtzheimer PE,Garlow SJ,Mayberg HS

doi

10.1016/j.wneu.2012.11.074

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

S27.e25-34

issue

3-4

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(12)01436-2

journal_volume

80

pub_type

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