Abstract：
OBJECTIVE:Patients with diffuse low-grade gliomas (DLGGs) typically present with seizures. We sought to review the neurosurgical literature for seizure outcome after resection of these tumors. METHODS:Using PubMed, we identified surgical series reporting seizure freedom rates for grade II astrocytoma, oligoastrocytoma, and oligodendroglioma. Inclusion criteria included seizure outcomes reported specifically for DLGGs and at least 10 patients with follow-up data. RESULTS:Twelve articles met the inclusion criteria. The median seizure-free rate after surgery in these patients was 71%, with an interquartile range of 64%-82%. In 10 studies, more than 60% of patients were seizure free. Studies used varying reporting times for seizure outcome determination. In the 6 studies that reported postoperative antiepileptic medication use, 5%-69% of seizure-free patients were weaned off these agents (median, 32%). The durability of seizure freedom has not been clearly studied to date. The most commonly reported prognostic factor for seizure freedom after resection was increasing extent of resection. CONCLUSIONS:Among articles reporting seizure outcomes after resection of DLGG, the median seizure-free rate was 71% (interquartile range, 64%-82%). Seizure freedom is likely associated with extent of resection.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Bonney PA,Boettcher LB,Burks JD,Baker C,Conner AK,Fujii T,Mehta VA,Briggs RG,Sughrue MEdoi
10.1016/j.wneu.2017.06.144subject
Has Abstractpub_date
2017-10-01 00:00:00pages
750-756eissn
1878-8750issn
1878-8769pii
S1878-8750(17)31041-0journal_volume
106pub_type
杂志文章,评审abstract：OBJECTIVE:The aim of the study was to examine the clinical effect of postoperative hyperbaric oxygen (HBO) therapy on symptoms and signs in the ventriculoperitoneal (VP) shunt insertion treatment of idiopathic normal pressure hydrocephalus (iNPH). METHODS:We conducted a retrospective analysis of 61 patients treated at...
journal_title：World neurosurgery
pub_type： 杂志文章
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journal_title：World neurosurgery
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abstract：BACKGROUND:Although syphilis has become a rare disease in the Western world since the Second World War, it is believed to have infected 12 million people in 1999, with greater than 90% of cases occurring in the developing world. Moreover, since the year 2000, the rates of syphilis have been increasing in the United Sta...
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abstract：BACKGROUND:Intracranial pseudoaneurysm is a rare complication of endoscopic endonasal surgery. Herein, we describe 2-staged stent-assisted coil embolization for posterior communicating artery pseudoaneurysm after endoscopic endonasal surgery for pituitary adenoma. CASE DESCRIPTION:A 68-year-old man had a history of se...
journal_title：World neurosurgery
pub_type： 杂志文章
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journal_title：World neurosurgery
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pub_type： 历史文章,杂志文章,评审
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更新日期：2013-02-01 00:00:00
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更新日期：2019-06-01 00:00:00
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更新日期：2019-01-10 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2017-01-01 00:00:00
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更新日期：2019-12-01 00:00:00
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更新日期：2019-01-01 00:00:00
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journal_title：World neurosurgery
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更新日期：2014-07-01 00:00:00
