Oxygen consumption in fetal lambs after maternal administration of sodium pentobarbital.

Abstract:

:To determine whether anesthesia lowers fetal oxygen consumption, sodium pentobarbital (10 mg/kg) was given intravenously to seven chronically instrumented pregnant ewes (123 to 144 days' gestation). Oxygen consumption fell by 23% in association with a rise in fetal vascular PO2. Fetal breathing movements were abolished for 50.5 minutes, while the number of fetal heart rate accelerations fell by 80% in the first 30 minutes after pentobarbital injection. It is concluded that anesthesia reduces fetal oxygen consumption, probably by abolishing skeletal muscle activity, and perhaps also by reducing cerebral metabolic rate.

journal_name

Am J Obstet Gynecol

authors

Rurak DW,Taylor SM

doi

10.1016/0002-9378(86)90628-9

subject

Has Abstract

pub_date

1986-03-01 00:00:00

pages

674-8

issue

3

eissn

0002-9378

issn

1097-6868

pii

0002-9378(86)90628-9

journal_volume

154

pub_type

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