Ultrasound measurement of fetal adrenal gland enlargement: an accurate predictor of preterm birth.

Abstract:

OBJECTIVE:The objective of the study was to test whether ultrasound-measured fetal adrenal gland volume (AGV) and fetal zone enlargement (FZE) predicts preterm birth (PTB) better than cervical length (CL). STUDY DESIGN:Three-dimensional and 2-dimensional ultrasound were used prospectively to measure fetal AGV, FZE, and CL in women with preterm labor symptoms. We corrected AGV for fetal weight (cAGV). The ratio between whole gland depth (D) and central fetal zone depth (d) (d/D) was used to measure FZE. Ability of cAGV, d/D, and CL to predict PTB 7 days or less was compared. RESULTS:Twenty-seven of 74 women (36.5%) presenting between 21 and 34 weeks had PTB of 7 days or less. FZE greater than 49.5% was the single best predictor for PTB (sensitivity/specificity 100%/89%) compared with cAGV (81%/87%) and CL (56%/60%; P < .05). Prediction was independent of obstetrics history and tocolytic use. CONCLUSION:The 2-dimensional measurement of the adrenal gland FZE is highly effective performing superior to CL in identifying women at risk for PTB within 7 days.

journal_name

Am J Obstet Gynecol

authors

Turan OM,Turan S,Funai EF,Buhimschi IA,Campbell CH,Bahtiyar OM,Harman CR,Copel JA,Buhimschi CS,Baschat AA

doi

10.1016/j.ajog.2010.11.034

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

311.e1-10

issue

4

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(10)02314-8

journal_volume

204

pub_type

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