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The epidemiologic incidence of congenital gastroschisis in Western Australia.

Abstract：

OBJECTIVE:The purpose of this study was to review the population incidence of congenital gastroschisis in Western Australia over the past 2 decades. STUDY DESIGN:A population-based incidence study of congenital gastroschisis from 1980 to 2001. Maternal and perinatal outcome data were collected to ascertain incidence, treatment, and outcome trends. RESULTS:One hundred twenty-two cases of gastroschisis were identified. The median maternal age was 23 years (range, 16-35 years). Women aged <20 years were at a 7.82 increased risk (95% CI, 4.34-14.08); women aged 20 to 24 years were at a 3.24 increased risk (95% CI, 1.88-5.61) for fetal gastroschisis compared with women aged >or=25 years. An incidence analysis over time indicated a significant increase of gastroschisis cases from 1 of 10,000 births during the period 1980-1990 to the current rate of 2.4 of 10,000 births (P<.001). The perinatal mortality rate was 12.7% (95% CI, 8.7-16.7) with a 9.8% stillbirth rate (95% CI, 6.3-13.3). CONCLUSION:There has been a sustained increase in the birth incidence of gastroschisis over the past decade, particularly in teenage women. A significant fetal death rate in the third trimester is observed.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Reid KP,Dickinson JE,Doherty DA

doi

10.1067/s0002-9378(03)00819-6

subject

Has Abstract

pub_date

2003-09-01 00:00:00

pages

764-8

issue

3

eissn

0002-9378

issn

1097-6868

pii

S0002937803008196

journal_volume

189

pub_type

杂志文章

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