当前位置： SCI文献检索 > TRANSPLANTATION PROCEEDINGS期刊下所有文献 > Monitoring of CD3(+) T-cell count in patients receiving antithymocyte globulin induction after cadaveric renal transplantation.

Monitoring of CD3(+) T-cell count in patients receiving antithymocyte globulin induction after cadaveric renal transplantation.

Abstract：

AIM:Although antithymocyte globulin (ATG) has been used for years, its ideal dose and administration period is obscure. Herein, we sought to use the CD3(+) cell count to detect the optimal ATG dosage. MATERIAL AND METHODS:Twenty-one patients who underwent cadaveric donor renal transplantation from January 2009 to January 2012 received a 1 mg/kg ATG initial dose at the time of the operation. Patients were randomized into 2 cohorts. Group 1 (n = 11) received ATG according to the clinical and total lymphocyte count and group 2 (n = 10), the dose was tailored according to the CD3(+) cell count. We compared the total and daily ATG dosages, ATG administration period, side effects of ATG, the number of days to a serum creatinine level <2 mg/dL, graft function at 3 months, acute rejection episodes, infection rates, costs of CD3(+) analysis, and ATG amounts. RESULTS:Both groups showed similar gender, age, and human leukocyte antigen matching data. There was no difference in presensitizing events or panel-reactive antibody class 1 and 2 levels. The number of days to a serum creatinine level of <2 mg/dL was 11 ± 1.5 for group 1 versus 10.4 ± 0.8 for group 2 (P = .45). Between groups 1 and 2, there was a significant difference between the mean total (P = .031) and mean daily ATG dosages (P = .006). We used a total dose of 3800 mg ATG for group 1 and 2200 mg for group 2 and for the group 2 who underwent 43 CD3(+) cell counts. The expenditure per patient was 20% higher among group 1 than group 2. CONCLUSION:Determination of appropriate ATG dosages by CD3(+) cell counts was useful, reliable, and cost effective.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Ata P,Kara M,Özdemir E,Canbakan M,Gökçe AM,Bayraktar FA,Şahin G,Özel L,Titiz MI

doi

10.1016/j.transproceed.2013.02.092

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

929-31

issue

3

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(13)00281-9

journal_volume

45

pub_type

杂志文章

相关文献

TRANSPLANTATION PROCEEDINGS文献大全
  • Dendritic cell therapy in composite tissue allotransplantation.

    abstract：:Dendritic cells (DCs) are bone marrow-derived, professional antigen-presenting cells, with inherent tolerogenic function. The ability of immature or maturation-resistant DCs to regulate alloantigen-specific T-cell responses and to promote tolerance induction has been well demonstrated in organ and bone marrow transpla...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2009.01.011

    authors： Thomson AW,Sacks JM,Kuo YR,Ikeguchi R,Horibe EK,Unadkat J,Solari MG,Feili-Hariri M,Lee WP

    更新日期：2009-03-01 00:00:00

  • Clinical diagnosis and management of the renal transplant recipient with cyclosporine nephrotoxicity.

    abstract：:The definition of CsA-induced nephrotoxicity is defined as impairment of renal function after transplantation exclusive of allograft rejection, vascular obstruction, and ureteral obstruction. This imprecise definition is one of exclusion and requires a careful clinical assessment of the patient, using information from...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：

    authors： Diethelm AG

    更新日期：1986-04-01 00:00:00

  • Assessment of gastrointestinal motility in renal transplant recipients by alternate current biosusceptometry.

    abstract：BACKGROUND:Gastrointestinal (GI) complications are common after renal transplantation, mainly owing to immunosuppressive therapy. Assessment of GI transit time can facilitate rational management of these disorders. OBJECTIVE:We evaluate the GI transit parameters in renal transplant recipients taking tacrolimus, azathi...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2012.07.048

    authors： Teixeira MC,Magalhães I,Galvão PV,Souza GS,Miranda JR,Oliveira RB,Corá LA

    更新日期：2012-10-01 00:00:00

  • Efficacy of Ultralow-Dose Valganciclovir Chemoprophylaxis for Cytomegalovirus Infection in ABO-Incompatible Kidney Transplantation Recipients.

    abstract：BACKGROUND:Cytomegalovirus (CMV) infection can increase morbidity and mortality in kidney transplant (KT) patients. Chemoprophylaxis with valganciclovir (VGCV) is recommended for ABO-incompatible (ABOi) KT patients as it significantly reduces CMV disease and infection. The recommended dose of VGCV for prevention of CMV...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2018.04.010

    authors： Lee JH,Hwang SD,Song JH,Kim JH,Kim HY,Lee DY,Oh JS,Sin YH,Kim JK

    更新日期：2018-10-01 00:00:00

  • A Single-center Experience on the Value of Pancreas Graft Biopsies and HLA Antibody Monitoring After Simultaneous Pancreas-Kidney Transplantation.

    abstract：BACKGROUND:In simultaneous pancreas-kidney transplantation (SPKT), monitoring of the pancreas allograft is more complex than the kidney allograft due to difficulties in obtaining pancreas histology and weak clinical evidence supporting the role of donor-specific antibodies (DSA). METHODS:We performed a single-center r...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2015.09.013

    authors： Becker LE,Hallscheidt P,Schaefer SM,Klein K,Grenacher L,Waldherr R,Macher-Goeppinger S,Schemmer P,Mehrabi A,Suesal C,Zeier M,Morath C

    更新日期：2015-10-01 00:00:00

  • Correlation between fibroscan, liver biopsy, and clinical liver function in patients with hepatitis C virus infection after renal transplantation.

    abstract：:Hepatitis C virus (HCV) infection is the most important liver disease (LD) after renal transplantation. Liver biopsy is the gold standard for the diagnosis and follow-up of LD. The aim of this retrospective study was to evaluate the correlation between values of Fibroscan (EchoSens, Paris, France), a new noninvasive m...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2009.06.103

    authors： Muñoz R,Ramírez E,Fernandez I,Martin A,Romero M,Romero E,Dominguez-Gil B,Hernandez A,Morales E,Andres A,Castellano G,Morales JM

    更新日期：2009-07-01 00:00:00

  • Structural and Functional Adaptation of the Remnant Kidney After Living Kidney Donation: Long-Term Follow-up.

    abstract：OBJECTIVE:Several adjustments occur after nephrectomy (NT) in the donor's remnant kidney. We investigated kidney donors 10 years after NT and compared several parameters before and after transplantation. METHODS:A total of 42 kidney donors of the University of Luebeck's Transplant Center were scheduled for a 10-year f...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2017.07.007

    authors： Meier M,Winterhoff J,Fricke L,Lehnert H,Nitschke M

    更新日期：2017-11-01 00:00:00

  • Comparison of clinical and pathological staging and long-term results of liver transplantation for hepatocellular carcinoma in a single transplant center.

    abstract：:Liver transplantation (OLT) is a treatment for hepatocellular carcinoma (HCC) superimposed on cirrhosis provided that the disease meets defined criteria. The aim of the study was to evaluate our experience with respect to clinical and pathological staging and long-term results. From 1996 to 2005, 50 patients underwent...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2006.02.015

    authors： Baccarani U,Adani GL,Avellini C,Lorenzin D,Currò G,Beltrami A,Pasqualucci A,Bresadola V,Risaliti A,Viale PL,Beltrami CA,Bresadola F

    更新日期：2006-05-01 00:00:00

  • C4d analysis in endomyocardial biopsies of heart transplant patients: is there a correlation with hemodynamic data?

    abstract：BACKGROUND:Endomyocardial biopsy (EMB) is the gold standard for immunologic follow-up to detect acute cellular rejection after cardiac transplantation. Conversely, protocols for the diagnosis and treatment of antibody-mediated rejection (AMR) are not well defined. Histologically, AMR is diagnosed by the presence of cap...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2011.03.021

    authors： Boffini M,Ricci D,Bonato R,Ribezzo M,Simonato E,Saviolo R,Checco L,Comoglio C,Rinaldi M

    更新日期：2011-05-01 00:00:00

  • Donors older than 70 years in liver transplantation.

    abstract：INTRODUCTION:Expansion of donor criteria has become necessary with the increasing number of liver transplantation candidates, as aged donors who have been considered to yield marginal organs. METHODS:Our database of 477 liver transplants (OLT) included 55 cases performed from donors at least 70 years old vs 422 with y...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.10.040

    authors： Gastaca M,Valdivieso A,Pijoan J,Errazti G,Hernandez M,Gonzalez J,Fernandez J,Matarranz A,Montejo M,Ventoso A,Martinez G,Fernandez M,de Urbina JO

    更新日期：2005-11-01 00:00:00

  • Vaccination Against Urinary Tract Infection After Renal Transplantation.

    abstract：BACKGROUND:Recurrent urinary tract infections (UTIs) increase mortality and reduce graft survival after renal transplantation. Because current prophylactic strategies such as methionine, cranberry juice, and antibiotics fail to sufficiently prevent recurrent infections in a substantial number of patients, there is a cl...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2020.06.018

    authors： Zgoura P,Waldecker C,Bauer F,Seibert FS,Rohn B,Schenker P,Wunsch A,Hajt S,Viebahn R,Babel N,Westhoff TH

    更新日期：2020-12-01 00:00:00

  • Update on Causes of Family Refusal for Organ Donation and the Related Factors: Reporting the Changes Over 6 Years.

    abstract：INTRODUCTION:After significant improvement of the family consent rate to organ donation (OD) in recent years, owing to an increase in cultural activities and social awareness, a plateau has been reached. This study was performed to detect the causes for this plateau. METHODS:We reviewed exact causes of family refusal ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2017.11.021

    authors： Mojtabaee M,Ghorbani F,Mohsenzadeh M,Beigee FS

    更新日期：2018-01-01 00:00:00

  • Mycobacterium abscessus infection in transplant recipients.

    abstract：BACKGROUND:Mycobacterium abscessus is a ubiquitous, rapidly growing mycobacterium that colonizes organic surfaces. It is a potential pathogen, especially in immunosuppressed patients, including transplant recipients in whom disease can range from localized cutaneous lesions to disseminated infections. The purpose of th...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2010.08.004

    authors： Morales P,Gil A,Santos M

    更新日期：2010-10-01 00:00:00

  • Causes for an Incomplete Donation Process at a Tertiary Care Hospital.

    abstract：INTRODUCTION:This study aims to identify the causes for the incomplete donation process at a tertiary care hospital. MATERIALS AND METHODS:A descriptive, retrospective study was performed; all potential donors reported to the Transplant Service within the period of 2005 to 2014 were included. Descriptive statistics we...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2016.02.021

    authors： Guerra-Sáenz EK,Narváez-Navarro AG,Hernández-López AC,Rojas-Delgado CE,Ruíz-Cantú G,Cordero-Pérez P,Hernández-Guedea M,Zapata-Chavira H,Escobedo-Villarreal MM,Muñoz-Espinosa L,Pérez Rodríguez E

    更新日期：2016-03-01 00:00:00

  • Development of functional human immune system with the transplantations of human fetal liver/thymus tissues and expanded hematopoietic stem cells in RAG2-/-gamma(c)-/- MICE.

    abstract：BACKGROUND:There is an increasing need for suitable animal models for the study of the human immune system and disease. The purpose of this study was to develop a practical in vivo model of human immune cell repopulation using ex vivo expanded human fetal liver-derived CD34(+) hematopoietic stem cells and subrenally co...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2009.02.074

    authors： Joo SY,Choi BK,Kang MJ,Jung DY,Park KS,Park JB,Choi GS,Joh J,Kwon CH,Jung GO,Lee SK,Kim SJ

    更新日期：2009-06-01 00:00:00

  • Posttransplant hypersplenism.

    abstract：:Posttransplant hypersplenism, manifested by leukopenia and azathioprine intolerance, can be diagnosed with a high degree of accuracy and promptly reversed by emergency splenectomy. Functioning cadaver kidney homograft survival rates in patients undergoing posttransplant splenectomy are equal to that of patients underg...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：

    authors： Kauffman HM Jr,Lawson RK,Adams MB,Sampson D

    更新日期：1979-03-01 00:00:00

  • Time frame of pancreas allograft rejection: an immunogenetic analysis in MHC-disparate, presensitized inbred rat strains.

    abstract：AIM:The pattern of rejection of vascularized pancreas allografts in presensitized recipients was studied among congeneic and recombinant rat strains in order to establish the time frame of rejection. Donors and recipients differed either in their entire MHC or in class I or class II MHC antigens. MATERIAL AND METHODS:...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2003.10.027

    authors： Litmathe J,Bektas H,Jörns A,Klempnauer J

    更新日期：2003-12-01 00:00:00

  • Stress dose steroids in renal transplant patients undergoing lymphocele surgery.

    abstract：:The requirement for perioperative stress dose steroids (SDS) in patients on long-term steroid therapy is controversial, but SDS are given during perioperative care. Studies focusing on surrogate outcomes like cortisol levels indicate a possible requirement for SDS, but clinical results are sparse. We retrospectively c...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.10.068

    authors： Mathis AS,Shah NK,Mulgaonkar S

    更新日期：2004-12-01 00:00:00

  • Effects of tacrolimus on antioxidant status and oxidative stress in glioma cells.

    abstract：OBJECTIVES:After organ transplantation, some patients suffer from mild neurologic symptoms, ranging from tremor to severe complications, including seizures and encephalopathy. Among the immunosuppressants, tacrolimus can cause neurologic side effects. However, the mechanisms of encephalopathy by tacrolimus are not full...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2008.08.006

    authors： Jin KB,Hwang EA,Han SY,Park SB,Kim HC,Ha EY,Suh SI,Mun KC

    更新日期：2008-10-01 00:00:00

  • Candida-associated denture stomatitis in patients after immunosuppression therapy.

    abstract：:Patients who undergo kidney or liver transplantation receive long-lasting immunosuppressive therapy. The resultant unfavorable symptoms result from immune deficiency and the side effects of the medications. The aim of this study was to establish the frequency and intensity of denture stomatitis and oral candidiasis am...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.12.078

    authors： Golecka M,Ołdakowska-Jedynak U,Mierzwińska-Nastalska E,Adamczyk-Sosińska E

    更新日期：2006-01-01 00:00:00

  • Correlational study between psychic symptoms and quality of life among hemodialysis patients older than 55 years of age.

    abstract：BACKGROUND:The loss of renal function and urination with dialysis can produce a strong emotional crisis in a patient. This study explored the correlation between psychic symptoms and quality of life among hemodialysis patients who were older than 55 years of age in relation to demographic characteristics of age, time o...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2012.06.015

    authors： De Pasquale C,Pistorio ML,Corona D,Mistretta A,Zerbo D,Sinagra N,Giaquinta A,Tallarita T,Esker B,Mociskyte D,Leonardi A,Gula R,Veroux P,Veroux M

    更新日期：2012-09-01 00:00:00

  • Knowledge of Chronic Hemodialysis Patients on Kidney Transplantation in Morocco.

    abstract：BACKGROUND:Kidney transplantation (KT) is the optimal treatment for chronic end-stage renal failure. However, it is experiencing a huge delay in Morocco, and the lack of information on this alternative treatment could contribute to this delay. The purpose of our work is to evaluate the knowledge of hemodialysis (HD) on...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.transproceed.2019.01.173

    authors： Karimi F,Chafai M,Fadili W,Laouad I,Lisri M,Habiballah M,Berrada M,Kaitouni AI

    更新日期：2019-09-01 00:00:00

  • Expression of receptor activator of nuclear factor-kappa B ligand in leukocytes during acute kidney rejection after transplantation in rats.

    abstract：BACKGROUND:Acute cellular rejection of the transplanted kidney is an important cause of impaired graft function. One of the basic characteristics of acute cellular rejection according to the latest Banff classification of renal allograft pathology is the presence of a large number of T lymphocytes in the allografted ti...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2012.10.065

    authors： Spanjol J,Celic T,Markic D,Djordjevic G,Maric I,Fuckar Z,Racki S,Bobinac D

    更新日期：2013-06-01 00:00:00

  • Impact of Splenectomy Just Before Partial Orthotopic Liver Transplantation Using Small-for-Size Graft in Rats.

    abstract：BACKGROUND:Portal hypertension is a serious obstacle of partial orthotopic liver transplantation (POLT) with the use of small-for-size liver graft. Several therapeutic strategies including surgical innovations and pharmacological agents to reduce the portal hypertension have been developed. Splenectomy (SP) on POLT is ...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2016.02.041

    authors： Kuriyama N,Iizawa Y,Kato H,Murata Y,Tanemura A,Azumi Y,Kishiwada M,Mizuno S,Usui M,Sakurai H,Isaji S

    更新日期：2016-05-01 00:00:00

  • Ethical evaluation of risks related to living donor transplantation programs.

    abstract：:The shortage of available cadaveric organs for transplantation and the growing demand has incresed live donation. To increase the number of transplantations from living donors, programs have been implemented to coordinate donations in direct or indirect form (cross-over, paired, and domino chain). Living donors with c...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2013.07.026

    authors： Panocchia N,Bossola M,Silvestri P,Midolo E,Teleman AA,Tazza L,Sacchini D,Minacori R,Di Pietro ML,Spagnolo AG

    更新日期：2013-09-01 00:00:00

  • Use of quality index in the evaluation of organ procurement and transplant programs in a University Hospital.

    abstract：AIM:To evaluate organ procurement efficiency at Hospital Clinic of Barcelona (HCP), a University Hospital, in 2000 and 2003 compared with other Catalan, other Spanish, and American (US) results. METHODS:Efficacy rate of the donor procurement was calculated per million population per year (pmp/y). Efficacy rate in kidn...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2005.08.052

    authors： Manyalich M,Mañalich R,Boni RC,Paredes D,Vilarrodona A,Vilardell J

    更新日期：2005-11-01 00:00:00

  • Sirolimus in pediatric renal transplantation.

    abstract：:Side effects of calcineurin inhibitors (CNIs) include nephrotoxicity and hypertension. Moreover, children have a higher risk of infections and posttransplantation lymphoproliferative disorders. We retrospectively evaluated the efficacy and safety of Sirolimus (SRL) in 18 patients, who were 10.52 +/- 5.03 years at time...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2004.12.242

    authors： Ibáñez JP,Monteverde ML,Goldberg J,Diaz MA,Turconi A

    更新日期：2005-03-01 00:00:00

  • Protective Role of the Portocaval Shunt in Liver Transplantation.

    abstract：BACKGROUND:Advances in medical management and surgical technique have resulted in stepwise improvements in early post-transplant survival rates. Modifications in the surgical technique, such as the realization of the portocaval shunt (PCS), could influence survival rates. The aim of this study was to evaluate the morta...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2020.01.089

    authors： Tortolero L,Nuño J,Buenadicha A,Gajate L,Serrano A,Liaño F,Peromingo R,Hervás PL

    更新日期：2020-06-01 00:00:00

  • Impact of live donor age (>or=50) on liver transplantation.

    abstract：BACKGROUND:The question of whether donor age negatively impacts recipient outcome in adult-to-adult living donor liver transplantation (LDLT) is rarely discussed. The aim of this study was to evaluate the impact of older donor age (50 years or older) on recipient outcomes in adult-to-adult LDLT. METHODS:LDLT data were...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2007.03.116

    authors： Akamatsu N,Sugawara Y,Tamura S,Kaneko J,Matsui Y,Togashi J,Makuuchi M

    更新日期：2007-12-01 00:00:00

  • Cytomegalovirus prophylaxis with intravenous polyvalent immunoglobulin in high-risk renal transplant recipients.

    abstract：:Cytomegalovirus (CMV) seronegative renal allograft recipients (R-), particularly those with a graft from a CMV-seropositive donor (D+), are at high risk for primary CMV infection. CMV resistance to antiviral oral therapy is an emerging problem in renal transplantation, prompting development of new prophylactic strateg...

    journal_title：Transplantation proceedings

    pub_type： 杂志文章

    doi：10.1016/j.transproceed.2006.07.001

    authors： Leroy F,Sechet A,Abou Ayache R,Thierry A,Belmouaz S,Desport E,Bauwens M,Bridoux F,Touchard G

    更新日期：2006-09-01 00:00:00