Abstract:
:Parkinson's disease (PD) is a devastating diagnosis with, however, potential for an extremely intriguing aesthetic component. Despite motor and cognitive deficits, an emerging collection of studies report a burst of visual artistic output and alterations in produced art in a subgroup of patients. This provides a unique window into the neurophysiological bases for why and how we might create and enjoy visual art, as well as into general brain function and the nature of PD or other neurodegenerative diseases. However, there has not been a comprehensive organization of literature on this topic. Nor has there been an attempt to connect case evidence and knowledge on PD with present understanding of visual art making in psychology and neuroaesthetics in order to propose hypotheses for documented artistic changes. Here, we collect the current research on this topic, tie this to PD symptoms and neurobiology, and provide new theories focusing on dopaminergic neuron damage, over-stimulation from dopamine agonist therapy, and context or genetic factors revealing the neurobiological basis of the visual artistic brain.
journal_name
Neurosci Biobehav Revjournal_title
Neuroscience and biobehavioral reviewsauthors
Lauring JO,Ishizu T,Kutlikova HH,Dörflinger F,Haugbøl S,Leder H,Kupers R,Pelowski Mdoi
10.1016/j.neubiorev.2018.12.016subject
Has Abstractpub_date
2019-05-01 00:00:00pages
129-165eissn
0149-7634issn
1873-7528pii
S0149-7634(18)30628-6journal_volume
100pub_type
杂志文章,评审abstract::Focused ultrasound (FUS) is a promising technology for facilitating treatment of brain diseases including chronic pain. Focused ultrasound is a unique modality for delivering therapeutic levels of energy into the body, including the central nervous system (CNS). It is non-invasive and can target spatially localized ef...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2020.06.007
更新日期:2020-08-01 00:00:00
abstract::Drawing on converging behavioral, electrophysiological, and imaging evidence, we advance an hypothesis for a cognitive phenotype of a SNP in the CHRNA4 gene encoding the α(4) subunit of α(4)β(2) nicotinic receptors. First, we review evidence that visuospatial attention can be decomposed into several component processe...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2012.02.010
更新日期:2012-04-01 00:00:00
abstract::Previous reviews have specifically looked at computer-based or Internet-based approaches. However, there has been no systematic review focused upon electronic communication based interventions for hazardous young drinkers. Out of 3298 relevant citations, 13 papers consisting of 11 studies met the inclusion criteria. E...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2016.07.021
更新日期:2016-09-01 00:00:00
abstract::Neural models of anatomical and functional alterations have been proposed for bipolar disorders (BD). However, studies in affected patients do not allow disentangling alterations linked to the liability to BD from those associated with the evolution, medication and comorbidities of BD. Explorations in high risk subjec...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2015.08.015
更新日期:2015-10-01 00:00:00
abstract::An increasing number of human electroencephalography (EEG) studies examining the earliest component of the visual evoked potential, the so-called C1, have cast doubts on the previously prevalent notion that this component is impermeable to top-down effects. This article reviews the original studies that (i) described ...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章
doi:10.1016/j.neubiorev.2010.12.011
更新日期:2011-04-01 00:00:00
abstract::Abundant evidence suggests links between trauma exposure, altered secretion of the glucocorticoid cortisol and the development/maintenance of posttraumatic stress disorder (PTSD), albeit with some inconsistency in findings. Further insight into the complex relations underlying this process may be derived from an incre...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2016.07.015
更新日期:2016-10-01 00:00:00
abstract::This model of hippocampal function describes the bilaterally symmetrical interactions of the various intrahippocampal populations of neurons that are functionally homogeneous (septal and entorhinal sources of input, granule cells, CA field pyramids cells, and basket cells). Activity of each homogeneous population is d...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章
doi:10.1016/0149-7634(80)90033-0
更新日期:1980-01-01 00:00:00
abstract::The role of prior stress experience on the response of the organism to a later stressor has been studied in terms of the extent of gastric ulceration induced by the second stressor. These studies have focused largely on effects of prior stress (shock, restraint, activity) on the ulceration developing under later restr...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/s0149-7634(05)80024-7
更新日期:1991-10-01 00:00:00
abstract::There is convincing evidence that schizophrenia is characterised by progressive brain volume changes during the course of the illness. In a large longitudinal study it was shown that different age-related trajectories of brain tissue loss are present in patients compared to healthy subjects, suggesting that brain matu...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2012.09.006
更新日期:2013-12-01 00:00:00
abstract::The present review discusses the history and paradigm of the conditioned avoidance response (CAR) in rats for the detection of potential antipsychotic activity of drugs. In addition, the role of dopamine (DA) D2, serotonin (5-HT)2A/2C, alpha1, 5-HT1A, DA D4, muscarinic and glutamate receptors in the suppression of CAR...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/s0149-7634(99)00037-8
更新日期:1999-01-01 00:00:00
abstract::We present a neurocognitive model of long-term object memory. We propose that perceptual priming and episodic recognition are phenomena based on three distinct kinds of representations. We label these representations types and tokens. Types are prototypical representations needed for object identification. The network...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2010.01.014
更新日期:2010-06-01 00:00:00
abstract::The effect of adding 0.125% saccharin to 3% or 32% solutions of Polycose, sucrose and glucose on the fluid intake and preference of adult female rats was examined. In Experiment 1, the rats consumed more of a 3% Polycose + 0.125% saccharin solution (P + s) than of either a 3% Polycose or 0.125% saccharin solution; sim...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章
doi:10.1016/s0149-7634(87)80030-1
更新日期:1987-07-01 00:00:00
abstract::One view of language origins sees it as ancient and selection-driven; the other as recent and emergent. Such disagreement occurs because language is ephemeral, detectable only by indirect proxies. Because internalized language and symbolic thought are tightly linked, the best archaeological proxies for language are sy...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2017.01.043
更新日期:2017-10-01 00:00:00
abstract::Exposure to maternal infection in utero increases the risk that offspring will develop neurodevelopmental disorders such as autism spectrum disorder (ASD) and schizophrenia. Research in animal models has confirmed this link and demonstrated that maternal immune activation (MIA) is sufficient to induce alterations in o...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章
doi:10.1016/j.neubiorev.2019.06.020
更新日期:2019-09-01 00:00:00
abstract::The aim of this systematic review was to summarize the effects of physical exercise on neuropathic pain (NP) in animal models of SCI. The search was conducted in Medline and Science Direct to identify experimental preclinical studies involving animal models of SCI, physical exercise as an intervention and the assessme...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,meta分析
doi:10.1016/j.neubiorev.2019.12.016
更新日期:2020-01-01 00:00:00
abstract::Post-stroke depression (PSD) is the most common mental health issue, afflicting around 33% of stroke survivors. PSD has a negative impact on the rehabilitation, recuperation of motor and cognitive deficits following stroke and significantly increases the chances of relapsing neurovascular events. It has been demonstra...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2018.04.005
更新日期:2018-07-01 00:00:00
abstract::Structure and function in the human brain are closely related. At the onset of psychosis, brain imaging studies have identified robust changes in brain function and structure, but no data are available relating these two domains. After systematic literature searches, we included all available studies reporting whole-b...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,meta分析
doi:10.1016/j.neubiorev.2012.07.012
更新日期:2012-11-01 00:00:00
abstract::Structural and functional magnetic resonance imaging modalities have been critical in advancing our understanding of the neuroanatomical and pathophysiological changes that emerge during the premanifest and symptomatic stages of Huntington's disease (HD). However, the relationship between underlying neuropathology and...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2013.05.009
更新日期:2013-09-01 00:00:00
abstract::Dopamine (DA) receptor supersensitivity refers to the phenomenon of an enhanced physiological, behavioral or biochemical response to a DA agonist. Literature related to ontogenetic aspects of this process was reviewed. Neonatal 6-hydroxydopamine (6-OHDA) destruction of rat brain DA neurons produces overt sensitization...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/0149-7634(94)00019-w
更新日期:1995-04-01 00:00:00
abstract::It is argued that both stimulus-response (S-R) and cognitive theories of learning and behaviour capture part of the truth, in that these terms involve two different types of process that are jointly responsible for the control of behaviour. The proposal that both processes coexist is investigated in the context of the...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/s0149-7634(97)00022-5
更新日期:1998-01-01 00:00:00
abstract::Numerous studies have documented a link between psychological disorders and cardiac disease. Yet, no systematic attempts have been made to develop pharmacological approaches for mood and anxiety disorders that could also be beneficial for cardiac health. The endocannabinoid system has been implicated in the regulation...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2016.04.013
更新日期:2017-03-01 00:00:00
abstract::This review summarizes functional magnetic resonance imaging (fMRI) research done over the past decade that examined changes in the function and organization of brain networks across human adolescence. Its over-arching goal is to highlight how both resting state functional connectivity (rs-fcMRI) and task-based functi...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2016.07.027
更新日期:2016-11-01 00:00:00
abstract::Within research into neurodevelopmental disorders, little is known about the mechanisms underpinning changes in symptom severity across development. When the behavioural presentation of a condition improves/symptoms lessen, this may be because core underlying atypicalities in cognition/neural function have ameliorated...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2017.06.005
更新日期:2017-09-01 00:00:00
abstract::This review describes the various subtypes of eating disorders and examines factors associated with the risk of illness. It considers evidence that the development and maintenance of eating disorders is due to gene-environment interactions (GxE) that alter genetic expression via epigenetic processes. It describes how ...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2010.09.012
更新日期:2011-01-01 00:00:00
abstract::Pentylenetetrazol (PTZ), a GABA(A) receptor antagonist and prototypical anxiogenic drug, has been extensively utilized in animal models of anxiety. PTZ produces a reliable discriminative stimulus which is largely mediated by the GABA(A) receptor. Several classes of compounds can modulate the PTZ discriminative stimulu...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/s0149-7634(02)00010-6
更新日期:2002-06-01 00:00:00
abstract::Behavioral sensitization is a progressive, enduring enhancement of behaviors that develops following repeated stimulant administration. It is mediated in part by dopaminergic pathways that also modulate a number of psychiatric conditions including the development of psychosis. We propose that down-regulation of D3 dop...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/s0149-7634(01)00023-9
更新日期:2001-07-01 00:00:00
abstract::Intermediate phenotypes may contribute to elucidate the genetic determinants of schizophrenia. A regulatory dopamine 2-receptor gene (DRD2) polymorphism (rs1076560; G>T) has been identified as a genetic risk factor for schizophrenia. Studies report conflicting results on its involvement in schizophrenia intermediate p...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.neubiorev.2017.01.006
更新日期:2017-03-01 00:00:00
abstract::The firing patterns of neurons in the nucleus accumbens (NA) are examined and discussed with respect to different types of rewards and reward conditions. Comparisons and contrasts between individually identified NA neuron responses to cocaine self-administration and water reinforcement are presented with an emphasis o...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2003.11.011
更新日期:2004-01-01 00:00:00
abstract::Memory formation is a highly dynamic process. In this review we discuss traditional views of memory and offer some ideas about the nature of memory formation and transformation. We argue that memory traces are transformed over time in a number of ways, but that understanding these transformations requires careful anal...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2012.03.001
更新日期:2012-08-01 00:00:00
abstract::Exposure to enriched environment has been shown to induce robust neuronal plasticity in both intact and injured adult central nervous system, including up-regulation of multiple neurotrophic factors, enhanced neurogenesis in the dentate gyrus of the hippocampus, and improved spatial learning and memory function. Neuro...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2007.10.004
更新日期:2008-01-01 00:00:00