Abstract:
:Sixty patients with recurrent inducible sustained ventricular tachycardia were prospectively treated with nadolol (40 or 80 mg/day). Old myocardial infarction was present in 43 patients and dilated cardiomyopathy in 12. In group I (n = 36), nadolol was given alone, whereas in group II (n = 24), previously ineffective treatment with amiodarone was continued in combination with nadolol. Left ventricular ejection fraction was higher in patients in group I (0.40 +/- 0.12) than in group II (0.30 +/- 0.10, p less than 0.01) patients. Electrophysiologic study was repeated after short-term treatment with nadolol, which was continued regardless of the results of this test, according to the scheme of the parallel approach. Recurrence of spontaneous tachycardia or sudden death occurred in 21 patients after 10 +/- 9.2 months; sustained tachycardia was inducible in 19 on nadolol therapy. The remaining 39 patients (of whom 21 had inducible tachycardia while taking the drug) have had no recurrence of tachycardia after 27.8 +/- 9.3 months of follow-up study. Sensitivity, specificity and predictive value of a positive and negative test were 90.5%, 46%, 47.5% and 90%, respectively. The results differ between group I and group II patients, the latter having a high percent of false positive responses. This difference is even more obvious with respect to left ventricular ejection fraction: the predictive value of a positive test was 86% when ejection fraction was greater than 0.40 and 39% when it was less than 0.40.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
J Am Coll Cardioljournal_title
Journal of the American College of Cardiologyauthors
Leclercq JF,Leenhardt A,Lemarec H,Clémenty J,Hermida JS,Sebag C,Aliot Edoi
10.1016/0735-1097(90)90594-fsubject
Has Abstractpub_date
1990-08-01 00:00:00pages
413-7issue
2eissn
0735-1097issn
1558-3597pii
0735-1097(90)90594-Fjournal_volume
16pub_type
杂志文章abstract:OBJECTIVES:We sought to assess the dynamic temporal course of conduction recovery during and after radiofrequency (RF) catheter ablation of the cavotricuspid isthmus. BACKGROUND:Although cavotricuspid isthmus block is accepted as the best end point of ablation for typical flutter, conduction recovery is thought to und...
journal_title:Journal of the American College of Cardiology
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更新日期:2000-05-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2000-01-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0735-1097(99)00018-2
更新日期:1999-04-01 00:00:00
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journal_title:Journal of the American College of Cardiology
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更新日期:1986-10-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,多中心研究
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更新日期:2018-04-24 00:00:00
abstract:OBJECTIVES:This study evaluated technetium-99m (Tc-99m) teboroxime kinetics in postischemic and partially necrotic myocardium with complete and low flow reperfusion using an isolated perfused rat heart model. BACKGROUND:Technetium-99m teboroxime has been proposed for use in the early diagnosis of reperfusion after thr...
journal_title:Journal of the American College of Cardiology
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更新日期:1996-08-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0735-1097(99)00340-x
更新日期:1999-10-01 00:00:00
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doi:10.1016/s0735-1097(98)00672-x
更新日期:1999-03-15 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/S0735-1097(96)00300-2
更新日期:1996-11-01 00:00:00
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journal_title:Journal of the American College of Cardiology
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更新日期:2018-06-12 00:00:00
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journal_title:Journal of the American College of Cardiology
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doi:10.1016/0735-1097(90)90328-m
更新日期:1990-12-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1997-08-01 00:00:00
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journal_title:Journal of the American College of Cardiology
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doi:10.1016/0735-1097(93)90719-h
更新日期:1993-01-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,评审
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更新日期:2007-10-16 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(99)00228-4
更新日期:1999-08-01 00:00:00
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更新日期:2012-02-14 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2018-04-24 00:00:00
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journal_title:Journal of the American College of Cardiology
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更新日期:1999-03-01 00:00:00
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更新日期:2010-10-26 00:00:00
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更新日期:2018-04-03 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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更新日期:1987-11-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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更新日期:2011-02-22 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(96)00454-8
更新日期:1997-01-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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更新日期:1990-04-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/j.jacc.2004.10.079
更新日期:2005-06-07 00:00:00
abstract:OBJECTIVES:We hypothesized that an amlodipine-based regimen would have more favorable effects on left ventricular (LV) diastolic function. BACKGROUND:Different antihypertensive therapies may vary in their effect on LV diastolic function. METHODS:The HACVD (Hypertension Associated Cardiovascular Disease) substudy of A...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/j.jacc.2009.11.084
更新日期:2010-04-27 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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更新日期:2001-05-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/j.jacc.2010.03.087
更新日期:2010-10-05 00:00:00