Cardiovascular disease risk in adults with spastic bilateral cerebral palsy.

Abstract:

OBJECTIVE:To explore: (i) cardiovascular disease risk factors and the 10-year clustered risk of a fatal cardiovascular event in adults with spastic bilateral cerebral palsy; and (ii) relationships between the 10-year risk and body fat, aerobic fitness and physical activity. DESIGN:Cross-sectional study. SUBJECTS:Forty-three adults with spastic bilateral cerebral palsy without severe cognitive impairment (mean age 36.6 years (standard deviation 6); 27 men). METHODS:Biological and lifestyle-related risk factors and the 10-year risk according to the Systematic Coronary Risk Evaluation (SCORE) were assessed. Relationships were studied using multivariable linear regression analysis. RESULTS:The following single risk factors were present: hypertension (n = 12), elevated total cholesterol (n = 3), low high-density lipoprotein cholesterol (n = 5; all men), high-risk waist circumference (n = 11), obesity (body mass index; n = 5; all men), reduced aerobic fitness (on average 80% of reference values), reduced level of everyday physical activity (on average 78% of reference values) and smoking (n=9). All participants had a 10-year risk <1%. Corrected for gender, participants with higher waist circumference (β = 0.28; p = 0.06) or body mass index (β=0.25; p = 0.08) tended to have a higher 10-year risk. CONCLUSION:In this relatively young adult sample of people with spastic bilateral cerebral palsy several single cardiovascular disease risk factors were present. The 10-year fatal cardiovascular disease risk was low, and higher body fat tended to be related to higher 10-year risk.

journal_name

J Rehabil Med

authors

van der Slot WM,Roebroeck ME,Nieuwenhuijsen C,Bergen MP,Stam HJ,Burdorf A,van den Berg-Emons RJ,MoveFit and Lifespan Research Group.

doi

10.2340/16501977-1185

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

866-72

issue

9

eissn

1650-1977

issn

1651-2081

journal_volume

45

pub_type

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