Treatment with Tie2-siRNA in combination with carboplatin suppresses the growth of Ishikawa human endometrial carcinoma cell xenografts in vivo.

abstract：:This study aims to comparatively analyze the impact of laparoscopic myomectomy (LM) and transcervical resection of myoma (TCRM) on ovarian function, immune function and quality of sexual life of patients with hysteromyoma. Two hundred and forty patients with hysteromyoma admitted into the Second Affiliated Hospital of...

journal_title：Oncology letters

authors： Zhang Y,Gu X,Meng Y,Guo H,Du J,Xing W

更新日期：2018-03-01 00:00:00

abstract：:The involvement of the female genital tract in transitional cell carcinoma (TCC) has not been fully elucidated in women, although involvement is usually associated with a poor prognosis. The vagina, in particular, is considered to be the most commonly affected gynecological organ, with an incidence of 4% of total TCC ...

journal_title：Oncology letters

authors： Aoun F,Kourie HR,El Rassy E,van Velthoven R

更新日期：2016-09-01 00:00:00

abstract：:The current case study aimed to explore the efficacy of a low-dose bevacizumab regimen in inhibiting tumor growth and minimizing adverse effects. A 55-year-old man with neurofibromatosis type 2 (NF2) suffered bilateral vestibular schwannomas (VS) measuring 5.25 and 2.54 cm3 on the left and right, respectively. His cap...

journal_title：Oncology letters

authors： Liu P,Yao Q,Li NA,Liu Y,Wang Y,Li M,Li Z,Li J,Li G

更新日期：2016-05-01 00:00:00

abstract：:This study investigated the inhibitory effect of vitamin D-binding protein-derived macrophage-activating factor (GcMAF) on carcinogenesis and tumor growth, using a 9,10-dimethyl-1,2-benzanthracene (DMBA)-induced hamster cheek pouch carcinogenesis model, as well as the cytocidal effect of activated macrophages against ...

journal_title：Oncology letters

authors： Toyohara Y,Hashitani S,Kishimoto H,Noguchi K,Yamamoto N,Urade M

更新日期：2011-07-01 00:00:00

abstract：:Low-grade cribriform cystadenocarcinoma (LGCCC) is a malignant salivary gland tumor. LGCCC occurs rarely, with the parotid gland being the most commonly afflicted site. Few cases arise in other sites. The present study reports a case of LGCCC that occurred at the palatal gland of the hard palate. A 56-year-old female ...

journal_title：Oncology letters

authors： Kokabu S,Nojima J,Kayano H,Yoda T

更新日期：2015-10-01 00:00:00

abstract：:Nanoparticle albumin-bound (nab)-paclitaxel appears to exhibit better response rates in patients with metastatic urothelial cancer of the bladder whom are pretreated with nab-paclitaxel compared with conventional paclitaxel. Paclitaxel may induce multidrug resistance in patients with cancer, while the mechanisms of re...

journal_title：Oncology letters

authors： Vallo S,Köpp R,Michaelis M,Rothweiler F,Bartsch G,Brandt MP,Gust KM,Wezel F,Blaheta RA,Haferkamp A,Cinatl J Jr

更新日期：2017-06-01 00:00:00

abstract：:Lung cancer is the leading cause of cancer-associated mortality worldwide and its prognosis is poor. Few effective biomarkers for non-small cell lung cancer (NSCLC) have been translated into the clinical practice aiming to assist in the treatment plan design and prognosis evaluation. The aim of the present study was t...

journal_title：Oncology letters

authors： Hao L,Du B,Xi X

更新日期：2017-08-01 00:00:00

abstract：:Macrophages are a heterogeneous group of phagocytes that play critical roles in inflammation, infection and tumor growth. Macrophages respond to different environmental factors and are thereby polarized into specialized functional subsets. Although hypoxia is an important environmental factor, its impact on human macr...

journal_title：Oncology letters

authors： Ke X,Chen C,Song Y,Cai Q,Li J,Tang Y,Han X,Qu W,Chen A,Wang H,Xu G,Liu D

更新日期：2019-12-01 00:00:00

abstract：:The present study aimed to clarify the association between kinesin family member 11 (KIF11) and human breast cancer, and the effect of KIF11 on breast cancer cell progression. Western blot analysis, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) analysis, retroviral infection, immunohistochemis...

journal_title：Oncology letters

authors： Pei YY,Li GC,Ran J,Wei FX

更新日期：2017-12-01 00:00:00

abstract：:The human ether-a-go-go-related potassium channel 1 (hERG1) is a component of the voltage-gated Kv11.1 potassium channel, which has been recently indicated to have a crucial role in the tumorigenesis of multiple tumors, including pancreatic carcinoma. Pancreatic carcinoma is one of the most malignant human cancer type...

journal_title：Oncology letters

authors： Zhi D,Zhao X,Dong M,Yan C

更新日期：2017-12-01 00:00:00

abstract：:The present study aimed to identify the level of programmed death-1 (PD-1) expression in infiltrating cluster of differentiation (CD)4+ and CD8+ T cells isolated from lung cancer tissues, and investigated whether the level of PD-1 expression may be directly regulated by lung cancer cells via prostaglandin E2 (PGE2)-as...

journal_title：Oncology letters

authors： Wang J,Zhang L,Kang D,Yang D,Tang Y

更新日期：2018-01-01 00:00:00

abstract：:Expression of copper-transporting P-type adenosine triphosphatase A (ATP7A) is reportedly associated with platinum drug resistance in various types of solid tumors. However, the impact of ATP7A expression on platinum drug resistance in non-small cell lung cancer (NSCLC) has yet to be adequately elucidated. In vitro ci...

journal_title：Oncology letters

authors： Inoue Y,Matsumoto H,Yamada S,Kawai K,Suemizu H,Gika M,Takanami I,Iwazaki M,Nakamura M

更新日期：2010-09-01 00:00:00

abstract：:The present study aimed to evaluate the diagnostic value of chromosomal analysis by fluorescence in situ hybridization (FISH) for bladder cancer in light of the histological diagnosis. Several valuable observations using FISH technologies in voided urine cells were also reported. The multi-target FISH-containing probe...

journal_title：Oncology letters

authors： Ke Z,Lai Y,Ma X,Lil S,Huang W

更新日期：2014-02-01 00:00:00

abstract：:Comprehensive gene screening with transposons is a novel procedure for the systematic identification of resistant genes. The present study aimed to use this technique to identify candidate radioresistant genes in esophageal squamous cell carcinoma. A transposon is a base sequence that can translocate to another locati...

journal_title：Oncology letters

authors： Takesue T,Kawakubo H,Hayashida T,Tsutsui M,Miyao K,Fukuda K,Nakamura R,Takahashi T,Wada N,Takeuchi H,Kitagawa Y

更新日期：2017-10-01 00:00:00

abstract：:The aim of the present study was to identify the differentially expressed microRNAs (DEMs) between Lynch syndrome (LS) and the normal colonic (N-C) control samples, predict the target genes (TGs) and analyze the potential functions of the DEMs and TGs. The miRNA expression dataset GSE30454, which included data of 13 L...

journal_title：Oncology letters

authors： Zhou C,Li J,Li J,Wan Y,Li T,Ma P,Wang Y,Sang H

更新日期：2016-09-01 00:00:00

abstract：:The present study aimed to investigate the impact of overexpression of long noncoding RNA PEG10 (lncRNA PEG10) on the proliferation, invasion and metastasis of hypopharyngeal squamous cell carcinoma (HSCC). Quantitative reverse transcription polymerase chain reaction was used to quantify lncRNA PEG10 expression levels...

journal_title：Oncology letters

authors： Zhao M,Sun D,Li X,Xu Y,Zhang H,Qin Y,Xia M

更新日期：2017-09-01 00:00:00

abstract：:Plumbagin, a naphthoquinone constituent of Plumbago zeylanica L. (Plumbaginaceae) is widely used in traditional Chinese medicine as an antifungal, antibacterial and anti-inflammatory agent. Plumbagin is known to exhibit proapoptotic, antiangiogenic and antimetastatic effects in cancer cells. The transcriptional co-fac...

journal_title：Oncology letters

authors： Xue YL,Meng XQ,Ma LJ,Yuan Z

更新日期：2016-08-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/ol.2019.10030.]. ...

journal_title：Oncology letters

authors： Wang S,Meng C,Jiang Z,Gonzalez-Rivas D,Ruan J,Xu W,Liu C,Zhang L,Gao G,Yu G,Teng H,Ju J

更新日期：2020-04-01 00:00:00

abstract：:Persistent infection with Helicobacter pylori may contribute to the carcinogenesis of gastric cancer through modulating local prostaglandin E2 (PGE2) levels. Cyclooxygenase-2 (COX-2) and 15-hydroxy prostaglandin dehydrogenase (15-PGDH) are two key enzymes that regulate PGE2 synthesis and inactivation, respectively. Th...

journal_title：Oncology letters

authors： Zhao J,Wen S,Wang X,Zhang Z

更新日期：2017-11-01 00:00:00

abstract：:Effect of crizotinib on apoptosis of lung cancer cells was investigated. Human non-small cell lung adenocarcinoma H2228 cells were cultured in the presence of 0, 20, 40, 80, 160 and 320 nmol/l of crizotinib for 3 days, respectively. The inhibition rate of cell proliferation was measured by MTT assay, and half maximal ...

journal_title：Oncology letters

authors： Lu H,Wu S,Chen H,Huang Y,Qiu G,Liu L,Li Y

更新日期：2018-11-01 00:00:00

abstract：:The transient receptor potential melastatin member 8 (TRPM8) is a newly characterized oncoprotein involved in various malignant tumors. However, its expression pattern and biological function in osteosarcoma remain unclear. The present study aimed to explore the expression and prognostic significance of TRPM8 in osteo...

journal_title：Oncology letters

authors： Zhao W,Xu H

更新日期：2016-08-01 00:00:00

abstract：:Patients with the luminal B subtype of breast cancer exhibit a poor prognosis, high metastatic risk and high incidence of chemotherapy resistance. Luminal B breast cancer is sub-classified into B1 and B2. The pathophysiological mechanism of luminal B2 breast cancer (LB2BC) progression has yet to be characterized. Ther...

journal_title：Oncology letters

authors： Wang J,Du Q,Li C

更新日期：2017-12-01 00:00:00

abstract：:The aim of this study was to investigate the correlation between H-ras mutation and primary hepatocellular carcinoma (HCC) and to describe the role of H-ras mutation in carcinogenesis. Clinical samples of 69 patients were collected and the expression levels of H-ras in HCC and the surrounding normal tissues were exami...

journal_title：Oncology letters

authors： Sui G,Ma X,Liu S,Niu H,Dong Q

更新日期：2012-10-01 00:00:00

abstract：:The present study aimed to investigate the effects of serum containing a combination of yi-qi-yang-yin-tang (YQYYT) and daunorubicin (DNR) on multidrug resistance in KG1a leukemia stem cells (LSCs). The effects of YQYYT and DNR on proliferation, cell cycle progression and the expression of phosphatase and tensin homol...

journal_title：Oncology letters

authors： Shi ZX,Li HY,Yang XD,Gao H,Li DG,Yang WH,Yao F,Yan LX

更新日期：2017-12-01 00:00:00

abstract：:Prostate cancer is the most common form of cancer in men, with increased incidence rates observed in older individuals. Prostate cancer is primarily driven via activation of the androgen receptor (AR), the principal transcriptional factor governing prostate cancer cellular programming and its associated metabolism. On...

journal_title：Oncology letters

authors： Dan C,Zhang H,Zeng W,Huang L,Gong X,Li H,Yang E,Wang L,Yao Q

更新日期：2019-01-01 00:00:00

abstract：:This study aimed to investigate the clinicopathological characteristics, differential diagnosis and prognosis of pulmonary epithelioid hemangioendothelioma (PEH). PEH is a rare low-grade malignant vascular tumor. The cause of PEH remains unclear. Patient prognosis is unpredictable, with life expectancy ranging from 1 ...

journal_title：Oncology letters

authors： Shao J,Zhang J

更新日期：2014-12-01 00:00:00

abstract：:Cancer affects multiple organs in the body Malignant melanoma involves the invasion of skin and occasionally mucosal membrane or eye choroidal tissues. The incidence of cutaneous malignant melanoma is on the increase worldwide and is a major concern in current research. The increase is associated with UV irradiation-i...

journal_title：Oncology letters

authors： Zhang XY,Zhang PY

更新日期：2016-11-01 00:00:00

abstract：:The IL-6R/JAK2/STAT3 pathway mediated by interleukin-6 (IL-6) plays an important role in the occurrence and development of multiple myeloma (MM), which is associated with decreased microRNA-451a. However, the biological function of microRNA-451a in MM remains unclear. The bone marrow (BM) of patients with MM was sampl...

journal_title：Oncology letters

authors： Zhong L,Xu Z,Jin X,He Y,Zhang J,Jiang T,Chen J

更新日期：2020-12-01 00:00:00

abstract：:Wilms tumor (WT) is the most common pediatric renal malignancy. A recent ontogenic model suggests that undifferentiated tumor state, and hence poor prognosis, in WT is determined by stabilization of β-catenin in the nucleus. Forkhead box M1 (FOXM1) is a downstream component of the Wnt pathway and promotes nuclear loca...

journal_title：Oncology letters

authors： Apelt N,Hubertus J,Mayr D,Graf N,Furtwängler R,Von Schweinitz D,Kappler R

更新日期：2016-10-01 00:00:00

abstract：:Numerous genetic alterations have been implicated in the development of prostate cancer (PCa). DNA and protein microarrays have enabled the identification of genes associated with apoptosis, which is important in PCa development. Despite the molecular mechanisms are not entirely understood, inhibition of apoptosis is ...

journal_title：Oncology letters

authors： Salemi M,Barone N,La Vignera S,Condorelli RA,Recupero D,Galia A,Fraggetta F,Aiello AM,Pepe P,Castiglione R,Vicari E,Calogero AE

更新日期：2016-10-01 00:00:00