Inhibition of growth of established human glioma cell lines by modulators of the protein kinase-C system.

abstract：:This series of 228 patients with infantile non-neoplastic hydrocephalus who received either a ventriculoatrial (VA) or a ventriculoperitoneal (VP) shunt before 2 years of age was followed for an average of 7 years, and the results with the two types of shunt were compared. Mortality and infection rates were similar fo...

journal_title：Journal of neurosurgery

authors： Keucher TR,Mealey J Jr

更新日期：1979-02-01 00:00:00

abstract：OBJECT:The authors retrospectively analyzed a consecutive series of patients with cranial vault primary extradural meningioma (PEM), with particular regard to the tumor's dural involvement. The pertinent literature was reviewed. METHODS:Clinical data were retrospectively obtained in a consecutive series of 16 patients...

journal_title：Journal of neurosurgery

authors： Bassiouni H,Asgari S,Hübschen U,König HJ,Stolke D

更新日期：2006-07-01 00:00:00

abstract：:The authors describe a case of intracranial heterotopic brain located on the medial one-third of the left sphenoid ridge, and enveloped in a huge cystic cavity. The heterotopic brain was resected successfully with satisfactory clinical results. The resected brain was 8 X 4 X 3 cm in diameter, of 7 or 8 months gestatio...

journal_title：Journal of neurosurgery

authors： Marubayashi T,Matsukado Y

更新日期：1978-03-01 00:00:00

abstract：:Thalamic, pallidal, and hypothalamic targets were determined in 16 patients by a stereotactic computerized tomography (CT) study using a noninvasive technique with Laitinen's Stereoadapter. At surgery, the Stereoadapter was remounted to the head and the stereotactic CT coordinates were transferred to the Stereoguide w...

journal_title：Journal of neurosurgery

authors： Hariz MI,Bergenheim AT

更新日期：1990-10-01 00:00:00

abstract：OBJECT:The aim of this study was to acquire intraoperative images during neurosurgical procedures for later reconstruction into a stereoscopic image system (QuickTime Virtual Reality [QTVR]) that would improve visualization of complex neurosurgical procedures. METHODS:A robotic microscope and digital cameras were used...

journal_title：Journal of neurosurgery

authors： Balogh A,Preul MC,Schornak M,Hickman M,Spetzler RF

更新日期：2004-04-01 00:00:00

abstract：:Recombinant gamma-interferon (2 mg/sq m) was administered intravenously twice weekly in 8-week courses to 14 patients with recurrent gliomas. Computerized tomography (CT) evidence of response was seen in only one patient, and stabilization for 12 to 86 weeks was recorded in three. This was a disappointing result, part...

journal_title：Journal of neurosurgery

authors： Mahaley MS Jr,Bertsch L,Cush S,Gillespie GY

更新日期：1988-12-01 00:00:00

abstract：OBJECTIVE:Superficial temporal artery-middle cerebral artery (STA-MCA) bypass is a common approach for treating moyamoya disease (MMD); however, the selection of recipient vessels is still controversial, and its relationship with postoperative cerebral hyperperfusion (CHP) has not been revealed. The aim of the study wa...

journal_title：Journal of neurosurgery

authors： Zhang J,Li S,Fujimura M,Lau TY,Wu X,Hu M,Zheng H,Xu H,Zhao W,Li X,Chen J

更新日期：2019-12-27 00:00:00

abstract：:The roles of hemoglobin (Hb) in the pathogenesis of cerebral vasospasm remain a matter of discussion. Hemoglobin is known to be released from extravasated red blood cells in a variety of pathological conditions, including subarachnoid hemorrhage. These conditions are often accompanied by infiltration of inflammatory c...

journal_title：Journal of neurosurgery

authors： Suzuki S,Takenaka K,Kassell NF,Lee KS

更新日期：1994-12-01 00:00:00

abstract：OBJECT:Using a database that enabled longitudinal follow-up, the authors assessed the long-term outcomes of unruptured cerebral aneurysms repaired by clipping or coiling. METHODS:An observational analysis of the California Office of Statewide Health Planning and Development (OSHPD) database, which follows patients lon...

journal_title：Journal of neurosurgery

authors： Gonda DD,Khalessi AA,McCutcheon BA,Marcus LP,Noorbakhsh A,Chen CC,Chang DC,Carter BS

更新日期：2014-06-01 00:00:00

abstract：:OBJECTIVE The Agency of Healthcare Research and Quality (AHRQ) has defined Patient Safety Indicators (PSIs) for assessments in quality of inpatient care. The hypothesis of this study is that, in the treatment of unruptured cerebral aneurysms (UCAs), PSI events are less likely to occur in hospitals meeting the volume t...

journal_title：Journal of neurosurgery

authors： Washington CW,Taylor LI,Dambrino RJ,Clark PR,Zipfel GJ

更新日期：2018-08-01 00:00:00

abstract：:A case of giant aneurysmal bone cyst of the skull is reported. Treatment was by total excision in three-staged surgery. The patient made a good recovery. ...

journal_title：Journal of neurosurgery

authors： Chalapati Rao KV,Rao BS,Reddy CP,Sundareshwar B,Reddy CR

更新日期：1977-10-01 00:00:00

abstract：OBJECT:To explore factors affecting the survival rate in patients with meningiomas, the authors used the National Cancer Data Base (NCDB), which includes tumors from approximately 1000 hospitals participating in the American College of Surgeons tumor registry program. METHODS:Analysis included over 9000 cases diagnose...

journal_title：Journal of neurosurgery

authors： McCarthy BJ,Davis FG,Freels S,Surawicz TS,Damek DM,Grutsch J,Menck HR,Laws ER Jr

更新日期：1998-05-01 00:00:00

abstract：:The water in normal and edematous brain tissues of rats was studied by the pulse nuclear magnetic resonance (NMR) technique, measuring the longitudinal relaxation time (T1) and the transverse relaxation time (T2). In the normal brain, T1 and T2 were single components, both shorter than in pure water. Prolongation and ...

journal_title：Journal of neurosurgery

authors： Naruse S,Horikawa Y,Tanaka C,Hirakawa K,Nishikawa H,Yoshizaki K

更新日期：1982-06-01 00:00:00

abstract：:A technique is described for removing previously placed aneurysm clips and applying new aneurysm clips for the treatment of regrown or reruptured cerebral aneurysms in patients more than 10 years after the original clipping of the aneurysm neck. The adherent tissue covering previously placed clips is cut just on and a...

journal_title：Journal of neurosurgery

authors： Kashimura H,Ogasawara K,Kubo Y,Otawara Y,Ogawa A

更新日期：2007-10-01 00:00:00

abstract：OBJECT:It is assumed that the observed increase in brain tumor incidence may at least partially be explained by increased use of MRI. However, to date no direct estimate of this effect is available. The authors undertook this registry-based study to examine whether regional frequencies of cerebral MRI use correlate to ...

journal_title：Journal of neurosurgery

authors： Solheim O,Torsteinsen M,Johannesen TB,Jakola AS

更新日期：2014-04-01 00:00:00

abstract：:A number of operative techniques have been described for the treatment of herniated thoracic discs. The transfacet pedicle-sparing approach allows for complete disc removal with limited spinal column disruption and soft-tissue dissection. Fifteen cadaveric spinal columns were used for evaluation of exposure, developme...

journal_title：Journal of neurosurgery

authors： Stillerman CB,Chen TC,Day JD,Couldwell WT,Weiss MH

更新日期：1995-12-01 00:00:00

abstract：:Mongrel dogs with experimental spinal cord injury were treated with the carotenoid compound crocetin. It has been shown that crocetin increases the diffusion speed of oxygen through plasma, and should provide a net increase in oxygen at the level of the capillary endothelial cell. The treated animals showed a signific...

journal_title：Journal of neurosurgery

authors： Gainer JV Jr

更新日期：1977-03-01 00:00:00

abstract：:OBJECTIVE WHO Grade III gliomas are relatively rare and treated with multiple modalities such as surgery, chemotherapy, and radiotherapy. The impact of the extent of resection (EOR) on improving survival in patients with this tumor type is unclear. Moreover, because of the heterogeneous radiological appearance of Grad...

journal_title：Journal of neurosurgery

authors： Fujii Y,Muragaki Y,Maruyama T,Nitta M,Saito T,Ikuta S,Iseki H,Hongo K,Kawamata T

更新日期：2018-07-01 00:00:00

abstract：:Protection of the brain and spinal cord against ischemia is a goal of vast clinical importance. One approach to this objective is to reduce the tissue's functional activity in order to preserve energy for the metabolic processes that are essential to viability. Experiments to explore ways of reducing function-related ...

journal_title：Journal of neurosurgery

authors： Zager EL,Ames A 3rd

更新日期：1988-10-01 00:00:00

abstract：:Parkinsonism caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) exposure was first identified in intravenous drug users. This neurotoxicant has since been used extensively in nonhuman primates to induce an experimental model of Parkinson disease (PD). In this study, the authors examined the intraoperative p...

journal_title：Journal of neurosurgery

authors： Christine CW,Langston JW,Turner RS,Starr PA

更新日期：2009-02-01 00:00:00

abstract：OBJECT:The expression of estrogen receptor-related antigen (ER-D5) has been demonstrated in many tumors, including those of the brain, but the actual role of ER-D5 in cell growth is unknown. The authors evaluated the role of ER-D5 in the growth of gliomas in vitro. METHODS:Human glioblastoma multiforme (GBM) cell line...

journal_title：Journal of neurosurgery

authors： Khalid MH,Shibata S,Furukawa K,Nadel A,Ammerman MD,Caputy AJ

更新日期：2004-05-01 00:00:00

abstract：:Local experimental subarachnoid hemorrhage (SAH) was produced over the cerebral cortex in 15 cats. The cellular response was monitored using ion-specific electrodes for extracellular potassium (K+) and calcium (Ca++) activity, DC cortical potential, and electrocorticogram. The response was characterized by a profound ...

journal_title：Journal of neurosurgery

authors： Hubschmann OR,Kornhauser D

更新日期：1982-02-01 00:00:00

abstract：OBJECT:The goal of this study was to establish the therapeutic window during which delayed therapy with MgSO4 improves neurological motor outcome in rats that have suffered severe traumatic axonal brain injury. METHODS:Severe brain injury was induced in male Sprague-Dawley rats by using the impact-acceleration model o...

journal_title：Journal of neurosurgery

authors： Heath DL,Vink R

更新日期：1999-03-01 00:00:00

abstract：OBJECT:The authors conducted a study to determine age-related changes in expression of transforming growth factor (TGF)-beta1, -beta2, -beta3, and Type I and Type II receptors in various cells in the nucleus pulposus and anulus fibrosus. Immunolocalization of TGFbetas and Type I and II receptors was examined during the...

journal_title：Journal of neurosurgery

authors： Matsunaga S,Nagano S,Onishi T,Morimoto N,Suzuki S,Komiya S

更新日期：2003-01-01 00:00:00

abstract：:The translabyrinthine route or an extension of it was used to remove 150 acoustic nerve tumors. The mortality was 2% and the morbidity low. Preservation of the facial nerve was achieved in 100% of the small and 80% of the medium-sized tumors, but in only 20% of the large growths. The complications encountered are disc...

journal_title：Journal of neurosurgery

authors： King TT,Morrison AW

更新日期：1980-02-01 00:00:00

abstract：OBJECT:The purpose of this study was to analyze patient outcomes and to define the role of radiosurgery in patients who have undergone prior microsurgical resection of their vestibular schwannoma. METHODS:The authors evaluated the pre- and postoperative clinical and neuroimaging characteristics of 76 consecutive patie...

journal_title：Journal of neurosurgery

authors： Pollock BE,Lunsford LD,Flickinger JC,Clyde BL,Kondziolka D

更新日期：1998-12-01 00:00:00

abstract：:The authors describe a previously unreported malformation involving paired, bilaterally symmetrical dermal sinus tracts in the retro-auricular area, both of which passed through the asterion and posterior fossa dura mater to end intracranially. Cranial dermal sinus tracts are congenital lesions that virtually always o...

journal_title：Journal of neurosurgery

authors： Nejat F,Dias MS,Eftekhar B,Roodsari NN,Hamidi S

更新日期：2003-07-01 00:00:00

abstract：:Nucleolar organizer regions (NOR's) are loops of deoxyribonucleic acid (DNA) which transcribe to ribosomal ribonucleic acid (RNA) by RNA polymerase I. They possess vital significance in the ultimate synthesis of cellular proteins. A silver colloid staining technique for demonstration of NOR-associated proteins (Ag-NOR...

journal_title：Journal of neurosurgery

authors： Shiraishi T,Tabuchi K,Mineta T,Momozaki N,Takagi M

更新日期：1991-06-01 00:00:00

abstract：:Pressure volume index (PVI) and cerebrospinal fluid (CSF) outflow resistance (Ro) were estimated in spontaneously breathing anestheized cats by the bolus injection test under normal conditions and also under abnormal conditions produced by slow infusion of saline into the CSF space. Bolus injections were made separate...

journal_title：Journal of neurosurgery

authors： Takizawa H,Gabra-Sanders T,Miller JD

更新日期：1986-02-01 00:00:00

abstract：:Excision is the treatment of choice in cases of sacral chordoma. Local recurrences, however, have often been observed even after total en bloc resection. The authors assessed outcomes in four cases of tumor recurrence in patients who underwent total en bloc S2-3 resection for sacral chordomas that were located below S...

journal_title：Journal of neurosurgery

authors： Ishii K,Chiba K,Watanabe M,Yabe H,Fujimura Y,Toyama Y

更新日期：2002-07-01 00:00:00