Use of crocetin in experimental spinal cord injury.

Abstract:

:Mongrel dogs with experimental spinal cord injury were treated with the carotenoid compound crocetin. It has been shown that crocetin increases the diffusion speed of oxygen through plasma, and should provide a net increase in oxygen at the level of the capillary endothelial cell. The treated animals showed a significant improvement in recovery rates as compared to controls.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Gainer JV Jr

doi

10.3171/jns.1977.46.3.0358

subject

Has Abstract

pub_date

1977-03-01 00:00:00

pages

358-60

issue

3

eissn

0022-3085

issn

1933-0693

journal_volume

46

pub_type

杂志文章
  • Cerebral hemispherectomy in pediatric patients with epilepsy: comparison of three techniques by pathological substrate in 115 patients.

    abstract:OBJECT:Cerebral hemispherectomy for intractable seizures has evolved over the past 50 years, and current operations focus less on brain resection and more on disconnection. In addition, cases involving cortical dysplasia and Rasmussen encephalitis are being identified and surgically treated in younger individuals. Few ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/ped.2004.100.2.0125

    authors: Cook SW,Nguyen ST,Hu B,Yudovin S,Shields WD,Vinters HV,Van de Wiele BM,Harrison RE,Mathern GW

    更新日期:2004-02-01 00:00:00

  • Gamma knife surgery for choroidal neovascularization in age-related macular degeneration. Technical note.

    abstract::The authors conducted a study to determine a way of overcoming the poor-quality demonstration of choroidal neovascularization (CNV) associated with age-related macular degeneration (AMD) on conventional magnetic resonance (MR) imaging studies. The poor MR imaging demonstration of CNV in patients with AMD makes the use...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2005.102.s_supplement.0200

    authors: Hayashi M,Chernov M,Usukura M,Abe K,Ono Y,Izawa M,Hori S,Hori T,Takakura K

    更新日期:2005-01-01 00:00:00

  • Brain tissue oxygen tension response to induced hyperoxia reduced in hypoperfused brain.

    abstract:OBJECTIVES:Increasing PaO2 can increase brain tissue PO2 (PbtO2). Nevertheless, the small increase in arterial O2 content induced by hyperoxia does not increase O2 delivery much, especially when cerebral blood flow (CBF) is low, and the effectiveness of hyperoxia as a therapeutic intervention remains controversial. The...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/JNS/2008/108/01/0053

    authors: Hlatky R,Valadka AB,Gopinath SP,Robertson CS

    更新日期:2008-01-01 00:00:00

  • Cortical calculation localization using electrostimulation.

    abstract:OBJECT:A naming task has been used to spare cortical areas involved in language. In the present study, a calculation task was combined with electrostimulation mapping (awake surgery) to spare cortical areas involved in calculation in patients undergoing surgery for brain lesions. The organization of language and calcul...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2008.8.JNS17649

    authors: Roux FE,Boukhatem L,Draper L,Sacko O,Démonet JF

    更新日期:2009-06-01 00:00:00

  • Long-term intraventricular baclofen infusion in beagles.

    abstract:OBJECT:This study was designed to evaluate the clinical and histopathological effects of long-term (3-month) intraventricular baclofen (IVB) infusion in beagle dogs. METHODS:Catheters were inserted stereotactically into the lateral ventricles of nine dogs and were connected to implanted Synchromed II pumps. Saline sol...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/PED-07/09/225

    authors: Albright AL

    更新日期:2007-09-01 00:00:00

  • A retrospective cohort-matched comparison of conscious sedation versus general anesthesia for supratentorial glioma resection. Clinical article.

    abstract:OBJECT:Glioma resection under conscious ("awake") sedation (CS) is used for eloquent areas of the brain to minimize postoperative neurological deficits. The objective of this study was to compare the duration of hospital stay, overall hospital cost, perioperative morbidity, and postoperative patient functional status i...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2010.5.JNS1041

    authors: Peruzzi P,Bergese SD,Viloria A,Puente EG,Abdel-Rasoul M,Chiocca EA

    更新日期:2011-03-01 00:00:00

  • Long-term follow-up study of unruptured vertebral artery dissection: clinical outcomes and serial angiographic findings.

    abstract:OBJECT:Although the spontaneous occurrence of an unruptured vertebral artery (VA) dissection has increasingly been recognized as a relatively common cause of stroke, and the clinical aspects of this lesion have gradually been determined, its natural course remains obscure. The main goal of this study was to clarify the...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2000.93.1.0019

    authors: Nakagawa K,Touho H,Morisako T,Osaka Y,Tatsuzawa K,Nakae H,Owada K,Matsuda K,Karasawa J

    更新日期:2000-07-01 00:00:00

  • Treatment of nontraumatic atlantoaxial dislocation and fibrous fusion. Case report.

    abstract::The authors describe a case of nontraumatic atlantoaxial dislocation secondary to acute rheumatic fever, in which there appeared to be fibrous fusion between the axis and the atlas in the subluxed position. The dislocation was reduced by means of combined traction and steroid therapy. Fibrous fusion occurred in the re...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1982.56.1.0139

    authors: Lucas JT,Hungerford GD,Perot PL Jr

    更新日期:1982-01-01 00:00:00

  • Use of a Peltier chip with a newly devised local brain-cooling system for neocortical seizures in the rat. Technical note.

    abstract::Local cortical cooling for termination of epileptic discharges (EDs) has recently become a focus of research. The authors report on a newly devised cooling system that uses a thermoelectric (Peltier) chip and examine the system's performance in experimental neocortical seizures. Experiments were performed in adult mal...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2006.104.1.150

    authors: Imoto H,Fujii M,Uchiyama J,Fujisawa H,Nakano K,Kunitsugu I,Nomura S,Saito T,Suzuki M

    更新日期:2006-01-01 00:00:00

  • Posttrauma cotreatment with lithium and valproate: reduction of lesion volume, attenuation of blood-brain barrier disruption, and improvement in motor coordination in mice with traumatic brain injury.

    abstract:OBJECT:Although traumatic brain injury (TBI) is the leading cause of death and morbidity in young adults, no effective pharmaceutical treatment is available. By inhibiting glycogen synthase kinase-3 (GSK-3) and histone deacetylases (HDACs), respectively, lithium and valproate (VPA) have beneficial effects in diverse ne...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2013.6.JNS13135

    authors: Yu F,Wang Z,Tanaka M,Chiu CT,Leeds P,Zhang Y,Chuang DM

    更新日期:2013-09-01 00:00:00

  • Comparison of flow diversion with clipping and coiling for the treatment of paraclinoid aneurysms in 115 patients.

    abstract::OBJECTIVEParaclinoid aneurysms represent approximately 5% of intracranial aneurysms (Drake et al. [1968]). Visual impairment, which occurs in 16%-40% of patients, is among the most common presentations of these aneurysms (Day [1990], Lai and Morgan [2013], Sahlein et al. [2015], and Silva et al. [2017]). Flow-divertin...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2018.1.JNS171774

    authors: Silva MA,See AP,Khandelwal P,Mahapatra A,Frerichs KU,Du R,Patel NJ,Aziz-Sultan MA

    更新日期:2018-06-01 00:00:00

  • Diagnosis of superior sagittal sinus thrombosis by computerized tomography. Report of two cases.

    abstract::Superior sagittal sinus thrombosis was diagnosed on computerized tomography (CT) scanning and was subsequently confirmed by angiography in two patients. Small ventricles and filling defects occurring within the sinus (the empty triangle sign) appeared to be highly suggestive of superior sagittal sinus thrombosis, and ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1984.61.6.1129

    authors: d'Avella D,Russo A,Santoro G,Pandolfo N,Cafarelli F,De Blasi F,del Vivo RE

    更新日期:1984-12-01 00:00:00

  • Brain injury from a spent bullet descending vertically. Report of five cases.

    abstract::This is a report of five cases in which a bullet penetrated the vertex of the skull and brain, apparently during its vertical descent after having been fired into the air. ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1971.34.2part1.0222

    authors: Hanieh A

    更新日期:1971-02-01 00:00:00

  • Resolution of brain edema in severe brain injury at controlled high and low intracranial pressures.

    abstract::A series of 87 patients with severe brain injury were studied. Intracranial pressure (ICP) monitoring and external ventricular drainage were used to control ICP at high and low levels. Clearance of ytterbium-169-labeled diethylenetriaminepentaacetic acid (169Yb-DTPA), Evans blue dye, and ventricular cerebrospinal flui...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1984.61.4.0707

    authors: Cao M,Lisheng H,Shouzheng S

    更新日期:1984-10-01 00:00:00

  • The International Cooperative Study on the Timing of Aneurysm Surgery. Part 1: Overall management results.

    abstract::The International Cooperative Study on the Timing of Aneurysm Surgery evaluated the results of surgical and medical management in 3521 patients between December, 1980, and July, 1983. At admission, 75% of patients were in good neurological condition and surgery was performed in 83%. At the 6-month evaluation, 26% of t...

    journal_title:Journal of neurosurgery

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.3171/jns.1990.73.1.0018

    authors: Kassell NF,Torner JC,Haley EC Jr,Jane JA,Adams HP,Kongable GL

    更新日期:1990-07-01 00:00:00

  • Holographic interferometry applied to the study of the human skull.

    abstract::A laboratory technique that allows strain measurements of the skull is described. Holographic interferometry allows the entire surface displacement of the skull to be mapped within 1/10 of the wavelength of light. Holographic interferometric pictures are presented following various stress applications to the skull. Th...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1980.52.6.0825

    authors: Spetzler RF,Spetzler H

    更新日期:1980-06-01 00:00:00

  • Body position and cerebrospinal fluid pressure. Part 2: clinical studies on orthostatic pressure and the hydrostatic indifferent point.

    abstract::Lumbar cerebrospinal fluid (CSF) pressure was recorded in 116 adult neurosurgical patients in the lateral and sitting positions. The level of zero CSF pressure while in the sitting position (ZPS) and hydrostatic indifferent point (HIP) for lateral and sitting positions were determined and referred to the craniospinal ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1976.44.6.0698

    authors: Magnaes B

    更新日期:1976-06-01 00:00:00

  • A new model of transient hindbrain ischemia in gerbils.

    abstract::A model of transient hindbrain ischemia in Mongolian gerbils is described. The vertebrobasilar junction of gerbils was exposed by a transcervical approach through the space between the atlas and occipital bone. The origin of the basilar artery was occluded by a clip, and the local cerebral blood flow (CBF) was measure...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1984.60.5.1054

    authors: Yamada K,Hayakawa T,Yoshimine T,Ushio Y

    更新日期:1984-05-01 00:00:00

  • Enhanced in vitro uptake and retention of 3H-tetraphenylphosphonium by nervous system tumor cells.

    abstract::Photodynamic therapy is a promising treatment for human brain tumors because of the selective retention of certain compounds by tumor cells. Certain lipophilic cationic compounds, such as tetraphenylphosphonium (TPP), are selectively taken up by a variety of carcinomas. Although preferential retention of TPP has been ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1991.74.1.0116

    authors: Steichen JD,Weiss MJ,Elmaleh DR,Martuza RL

    更新日期:1991-01-01 00:00:00

  • Chordoid meningioma with polyclonal gammopathy. Case report.

    abstract::The authors present a case of chordoid meningioma in a 55-year-old woman who manifested headache and personality change. Magnetic resonance imaging of the brain and cerebral angiography demonstrated a mass in the right frontal lobe that resembled a typical convexity meningioma. However, the pathological diagnosis was ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/jns.2001.94.1.0122

    authors: Lee DK,Kim DG,Choe G,Chi JG,Jung HW

    更新日期:2001-01-01 00:00:00

  • White matter fiber dissection of the optic radiations of the temporal lobe and implications for surgical approaches to the temporal horn.

    abstract:OBJECT:The aim of this anatomical study was to define more fully the three-dimensional (3D) relationships between the optic radiations and the temporal horn and superficial anatomy of the temporal lobe by using the Klingler white matter fiber dissection technique. These findings were correlated with established surgica...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2004.101.5.0739

    authors: Sincoff EH,Tan Y,Abdulrauf SI

    更新日期:2004-11-01 00:00:00

  • Gamma surgery in the treatment of nonsecretory pituitary macroadenoma.

    abstract:OBJECT:The authors report on a retrospective analysis of the imaging and clinical outcomes following gamma surgery in 100 patients with nonsecretory pituitary macroadenoma. METHODS:Between June 1989 and March 2004, 100 consecutive patients with nonsecretory pituitary macroadenoma were treated at the Lars Leksell Cente...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.2006.104.6.876

    authors: Mingione V,Yen CP,Vance ML,Steiner M,Sheehan J,Laws ER,Steiner L

    更新日期:2006-06-01 00:00:00

  • Outcome following aneurysm wrapping: a 10-year follow-up review of clipped and wrapped aneurysms.

    abstract::One hundred and eighty-one patients with single aneurysms involving the anterior circulation were treated either by wrapping (60 cases) or clipping (121 cases), and 96.1% of them were followed for 10 years. The rate of early rebleeding (less than 6 months) from wrapped aneurysms was 8.6% (confidence interval 1.4% to 1...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1989.70.6.0841

    authors: Todd NV,Tocher JL,Jones PA,Miller JD

    更新日期:1989-06-01 00:00:00

  • The effects of deep barbiturate coma on multimodality evoked potentials.

    abstract::The authors report their investigation of the effects of high-dose barbiturates on the multimodality evoked response in 9 cats. After baseline evoked responses were obtained, boluses of pentobarbital were infused intravenously at regular intervals, amounting to cumulative total doses of 9, 18, 27, 45, 63, 123, and 183...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1982.57.2.0178

    authors: Sutton LN,Frewen T,Marsh R,Jaggi J,Bruce DA

    更新日期:1982-08-01 00:00:00

  • Actinomycotic granuloma of the Gasserian ganglion with primary site in a dental root. Case report.

    abstract::An unusual case of cerebral actinomycosis of the Gasserian ganglion is reported. The location and the pathological diagnosis of granuloma are both extremely rare. The literature is briefly reviewed with special reference to similar reports. The manner of spread and the course of the disease are described. The present ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1981.54.4.0553

    authors: Perna E,Liguori R,Petrone G,Mannarino E

    更新日期:1981-04-01 00:00:00

  • Neurosurgery and consciousness: historical sketch and future possibilities.

    abstract::Neurosurgery has played an important role in the development of neuroscience and the science of consciousness. In this paper, the authors reflect on some of the historical contributions of neurosurgeons to the science of consciousness and discuss the ways in which clinical neurosurgery can contribute to the science of...

    journal_title:Journal of neurosurgery

    pub_type: 历史文章,杂志文章

    doi:10.3171/2012.6.JNS112136

    authors: Hasegawa H,Jamieson GA,Ashkan K

    更新日期:2012-09-01 00:00:00

  • Engorged epidural venous plexus and cervical myelopathy due to cerebrospinal fluid overdrainage: a rare complication of ventricular shunts. Case report.

    abstract::The authors report on a 17-year-old boy with cervical myelopathy from dilated epidural veins due to cerebrospinal fluid (CSF) overdrainage. The patient had a long-standing subdural-peritoneal shunt and presented with incapacitating spastic tetraparesis. Magnetic resonance imaging revealed significant cervical spinal c...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/ped.2007.106.3.227

    authors: Wolfe SQ,Bhatia S,Green B,Ragheb J

    更新日期:2007-03-01 00:00:00

  • Unoperated subdural hematomas. Long-term follow-up study by brain scan and electroencephalography.

    abstract::The authors report nine patients selected from over 100 patients with subdural hematomas successfully treated without surgery. These patients were followed for as long as 5 years. All had angiographically demonstrated subdural hematomas. Electroencephalograms (EEG) documented well the clinical improvement of the patie...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1976.44.5.0601

    authors: Lusins J,Jaffe R,Bender MB

    更新日期:1976-05-01 00:00:00

  • Treatment with transducible phosphopeptide analogues of the small heat shock-related protein, HSP20, after experimental subarachnoid hemorrhage: prevention and reversal of delayed decreases in cerebral perfusion.

    abstract:OBJECT:Delayed vasospasm is a significant cause of morbidity and mortality after subarachnoid hemorrhage (SAH). Proteomic therapeutics offers a new modality in which biologically active proteins or peptides are transduced into cells via covalent linkage to cell permeant peptides (CPPs). The hypothesis of this study was...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2009.7.JNS09730

    authors: Furnish EJ,Brophy CM,Harris VA,Macomson S,Winger J,Head GA,Shaver EG

    更新日期:2010-03-01 00:00:00

  • Propofol in the treatment of moderate and severe head injury: a randomized, prospective double-blinded pilot trial.

    abstract:OBJECT:Sedation regimens for head-injured patients are quite variable. The short-acting sedative-anesthetic agent propofol is being increasingly used in such patients, yet little is known regarding its safety and efficacy. In this multicenter double-blind trial, a titratable infusion of 2% propofol accompanied by low-d...

    journal_title:Journal of neurosurgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3171/jns.1999.90.6.1042

    authors: Kelly DF,Goodale DB,Williams J,Herr DL,Chappell ET,Rosner MJ,Jacobson J,Levy ML,Croce MA,Maniker AH,Fulda GJ,Lovett JV,Mohan O,Narayan RK

    更新日期:1999-06-01 00:00:00