Evidence-based treatment of chronic rhinosinusitis with nasal polyps.

abstract：BACKGROUND:Patients report that nasal congestion is the most bothersome symptom of allergic rhinitis (AR). Recently, a short, patient-reported congestion screener questionnaire, the Congestion Quantifier Seven-Item Test (CQ7), was developed to identify a level of congestion that may warrant patients seeking evaluation ...

journal_title：American journal of rhinology & allergy

authors： Stull DE,Meltzer EO,Krouse JH,Roberts L,Kim S,Frank L,Naclerio R,Lund V,Long A

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Allergen immunotherapy (AIT) has been in practice for more than 100 years. However, research in novel routes and delivery methods of immunotherapy to treat allergic rhinitis (AR) and conjunctivitis has only recently occurred in the United States, where the predominant form of AIT provided is largely via a su...

journal_title：American journal of rhinology & allergy

authors： Lee S,Nolte H,Benninger MS

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Cigarette smoke exposure (CSE) results in extensive inflammation in the upper and lower airways. Reactive oxygen species, such as superoxide, have been shown to be potent mediators of this inflammation. METHODS:Mucosal biopsy specimens were collected from patients undergoing sinonasal surgery and were used ...

journal_title：American journal of rhinology & allergy

authors： Mulligan RM,Atkinson C,Vertegel AA,Reukov V,Schlosser RJ

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Primary ciliary dyskinesia (PCD) is a congenital hereditary disease affecting 1/20,000-60,000 people that causes chronic sinusitis, bronchiectasis, sinus hypoplasia, secretory otitis media, and low fertility. The complexity and heterogeneity of the disease make diagnosis difficult. Although the genetic orig...

journal_title：American journal of rhinology & allergy

authors： Mata M,Lluch-Estellés J,Armengot M,Sarrión I,Carda C,Cortijo J

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Standardized allergen-specific immunotherapy (SIT) has been used in China for years. However, there is no extensive study of the safety of standardized SIT in Chinese patients until now. The aim of the current study is to perform a prospective and multicenter study to evaluate the systemic reactions (SRs) of...

journal_title：American journal of rhinology & allergy

authors： Chen J,Li B,Zhao Y,Zhang Q,Wan L,Liu J,Tian X,Li G,Zhou J,Zhang L,Wang P,Cheng Q,Liang J,Zhao P,Luo Z,He J,Lu H,Zhou Y,Zhang Y,Chen X,Pan F,Zhang Z,Zeng L,He B,Zeng Y,Xu X,Kong W

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Gelsolin is an actin-binding protein with multiple cellular functions including apoptosis and is reported to be down-regulated in various cancers and premalignant lesions. The objective of this study was to identify gelsolin and caspase-3 expression in inverted papilloma (IP) and investigate the role of gels...

journal_title：American journal of rhinology & allergy

authors： Cho JE,Park Wi,Kim DC,Kim HJ,Kim SW,Kang JM,Cho JH

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Over the past 10 years, the management of juvenile nasopharyngeal angiofibroma (JNA) has been redefined because of the improvement of transnasal skull base techniques. However, the limits of endoscopic resection still have to be fully defined. The purpose of this study was to report on a series of patients p...

journal_title：American journal of rhinology & allergy

authors： Bleier BS,Kennedy DW,Palmer JN,Chiu AG,Bloom JD,O'Malley BW Jr

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Computed tomography (CT) of the paranasal sinuses is the diagnostic reference standard for chronic rhinosinusitis and related inflammatory sinus pathology. Nasal nitric oxide (nNO) levels have been investigated as a diagnostic tool in sinus disease because it decreases with sinus obstruction. OBJECTIVE:The ...

journal_title：American journal of rhinology & allergy

authors： Oliver JD,Lim KG,O'Brien EK

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Major histocompatibility complex (MHC) class II is involved in T-cell activation, cytokine secretion, and induction of immune responses. Cytokines, staphylococcus super antigens, and eosinophil activation are proposed to play important roles in aspirin-exacerbated respiratory disease (AERD). OBJECTIVES:This...

journal_title：American journal of rhinology & allergy

authors： Esmaeilzadeh H,Nabavi M,Amirzargar AA,Aryan Z,Arshi S,Bemanian MH,Fallahpour M,Mortazavi N,Rezaei N

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:The impact of middle turbinate resection (MTR) on olfaction remains a point of debate in the current literature. Few studies have objectively evaluated olfactory cleft airflow following MTR; thus, the mechanism by which MTR may impact olfaction is poorly understood. It is not known whether the postsurgical c...

journal_title：American journal of rhinology & allergy

authors： Alam S,Li C,Bradburn KH,Zhao K,Lee TS

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:This study evaluates if there is any benefit of adding epinephrine to lidocaine in patients undergoing diagnostic rigid nasal endoscopy. A prospective, randomized, double-blinded study was performed. METHODS:Seventy patients were randomized to receive either 2% lidocaine or 2% lidocaine with 0.2% epinephrin...

journal_title：American journal of rhinology & allergy

authors： Al-Qudah M

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Although nasal peak flow measurements have been proposed as a simple alternative method to assess nasal patency, which of nasal peak expiratory flow or nasal peak inspiratory flow (NPEF/NPIF) or the peak expiratory flow index or peak inspiratory flow index (PEFI/PIFI; the ratios between nasal and oral PEF or...

journal_title：American journal of rhinology & allergy

authors： Kirtsreesakul V,Leelapong J,Ruttanaphol S

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Sinonasal papillomas are benign epithelial neoplasms arising from Schneiderian mucosa. The three subtypes, exophytic, oncocytic, and inverted (inverted papilloma [IP]), should be distinguished from one another histopathologically. This study (1) highlights the histopathological and clinical differences betwe...

journal_title：American journal of rhinology & allergy

authors： Vorasubin N,Vira D,Suh JD,Bhuta S,Wang MB

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to apply protein microarray technology to the study of sinonasal tissue and to identify differential protein expression in nasal polyps from aspirin-sensitive (AS) versus aspirin-tolerant (AT) patients with chronic rhinosinusitis (CRS) and CRS with nasal polyps (CRSwNPs). METHO...

journal_title：American journal of rhinology & allergy

authors： Zander KA,Saavedra MT,West J,Scapa V,Sanders L,Kingdom TT

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Although nasal steroids are the mainstay treatments in nasal polyposis, up to one-half of patients do not respond and need surgical treatment. This study aimed to evaluate whether oxymetazoline administration produces any additive effect on nasal steroid therapy and whether rebound congestion develops after ...

journal_title：American journal of rhinology & allergy

authors： Kirtsreesakul V,Khanuengkitkong T,Ruttanaphol S

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis is commonly treated with antihistamines. Monitoring improvement of airway inflammation noninvasively using nasal nitric oxide (nNO) would be clinically useful. To determine the anti-inflammatory effect of oral levocetirizine dihydrochloride (LC), we measured nNO and nasal eosinophils (nEos...

journal_title：American journal of rhinology & allergy

authors： Bautista AP,Eisenlohr CP,Lanz MJ

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis (AR) is currently the most prevalent allergic disease in children and adolescents. OBJECTIVE:Surveys conducted by population-based studies of East Asia revealed an increased prevalence of behavioral disorders in patients with AR. Thus, in this study, we explored the prevalence of attention...

journal_title：American journal of rhinology & allergy

authors： Feng B,Jin H,Xiang H,Li B,Zheng X,Chen R,Shi Y,Chen S,Chen B

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Smoking status has been established as a known irritant of the upper and lower respiratory tracts, leading to inflammation throughout the respiratory system. Tobacco smoking is one comorbidity encountered among chronic rhinosinusitis (CRS) patients. The histopathologic features of CRS and comorbid smoking st...

journal_title：American journal of rhinology & allergy

authors： Kuhar HN,Ganti A,Brown HJ,Gattuso P,Ghai R,Mahdavinia M,Batra PS,Tajudeen BA

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Patients report nasal congestion as the most bothersome seasonal allergic rhinitis (SAR) symptom. Measurement of this symptom in previous research has largely been based on subjective patient ratings. This study was designed to measure efficacy, onset, and duration of action of the corticosteroid mometasone ...

journal_title：American journal of rhinology & allergy

authors： Salapatek AM,Patel P,Gopalan G,Varghese ST

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Cell tight junction proteins create a barrier between airway epithelial cells to limit paracellular transport from the apical to basolateral surface. This barrier can impede the entry of respiratory pathogens and toxins from the airway lumen into the systemic circulation. Mast cell-mediated inflammation in t...

journal_title：American journal of rhinology & allergy

authors： Chang EH,Lee JH,Zabner J

更新日期：2010-03-01 00:00:00

abstract：:Chronic rhinosinusitis (CRS) is the second most common chronic medical condition in the United States. It represents a group of disorders characterized by inflammation of the nasal mucosa and paranasal sinuses of at least 12 weeks duration. CRS with or without nasal polyps is defined as inflammation of the nose charac...

journal_title：American journal of rhinology & allergy

authors： Settipane RA,Peters AT,Chandra R

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:A number of studies suggested that limited economical airborne allergy screening can successfully predict true respiratory allergy and be of use to primary care providers (PCPs) in improving the accuracy of their differential diagnosis and treatment of allergic rhinitis. More accurate diagnosis would lead to...

journal_title：American journal of rhinology & allergy

authors： Mansfield L,Hutteman HR,Tyson S,Enriquez A

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Biofilm formation has been implicated as an etiologic factor in the development of chronic rhinosinusitis (CRS). Nasal irrigation with surfactants including dilute baby shampoo have been proposed as an antibiofilm treatment for CRS patients. The effect of dilute baby shampoo on normal sinonasal mucosal funct...

journal_title：American journal of rhinology & allergy

authors： Isaacs S,Fakhri S,Luong A,Whited C,Citardi MJ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:CD203c is a basophil surface marker and its expression is rapidly up-regulated after cross-linking of high-affinity immunoglobulin E (IgE) receptor (FcepsilonR1) by an allergen. CD203c basophil activation tests have been studied for the in vitro diagnosis of several allergic conditions. However, there is li...

journal_title：American journal of rhinology & allergy

authors： Özdemir SK,Güloğlu D,Sin BA,Elhan AH,Ikincioğulları A,Mısırlıgil Z

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) has a multifactorial etiology, with a debate about the role of inhalant allergy in the pathogenesis of CRS. OBJECTIVE:This study assessed the impact of allergy status on externalized paranasal sinuses after tumor resection to determine if a predisposition to inhalant allergy bro...

journal_title：American journal of rhinology & allergy

authors： Ahmadi N,Christensen JM,Barham HP,Oakley GM,Sacks R,Harvey RJ

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Aspirin-exacerbated respiratory disease (AERD) affects 7% of asthmatics. Usual therapies are inadequate for asthma and/or nasal polyposis, leading to decreased quality of life. OBJECTIVE:Our objective was to evaluate the efficacy of dupilumab in AERD patients with uncontrolled, chronic rhinosinusitis with n...

journal_title：American journal of rhinology & allergy

authors： Mustafa SS,Vadamalai K,Scott B,Ramsey A

更新日期：2020-09-23 00:00:00

abstract：BACKGROUND:This study was designed to determine whether there is any correlation between results of the skin-prick test and the severity of symptoms in allergic rhinitis. METHODS:We retrospectively evaluated 150 patients with persistent or intermittent allergic rhinitis confirmed by positive skin tests and scaled fro...

journal_title：American journal of rhinology & allergy

authors： Tatar EC,Sürenoğlu UA,Saylam G,Işık E,Ozdek A,Korkmaz H

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Viral respiratory tract infections are associated with a significant burden of disease and represent one of the leading causes of mortality worldwide. The current Coronavirus Disease 2019 (COVID-19) pandemic highlights the devastating toll that respiratory viruses have on humanity and the desperate need to u...

journal_title：American journal of rhinology & allergy

authors： Yuen E,Gudis DA,Rowan NR,Nguyen SA,Schlosser RJ

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Ginseng (Panax ginseng C.A. Meyer) has been used in Asian countries for the treatment of various diseases. However, the mechanisms of liquid Panax ginseng (LG) on allergic inflammatory response in epidermal growth factor (EGF)-stimulated human airway epithelial cells remain largely unclear. METHODS:MUC5AC, ...

journal_title：American journal of rhinology & allergy

authors： Kim JH,Kang JW,Kim M,Lee DH,Kim H,Choi HS,Kim EJ,Chung IM,Chung IY,Yoon DY

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the amount and type of osteitis observed in chronic rhinosinusitis with nasal polyposis (CRSwNP) and compare it with that of chronic rhinosinusitis without nasal polyposis (CRSnNP). SETTING:Sisli Etfal Research and Education Hospital, Istanbul, Turkey. STUDY DESIGN:Prospective, single-blind, coh...

journal_title：American journal of rhinology & allergy

authors： Emre IE,Celebi I,Ercan I

更新日期：2015-11-01 00:00:00