Chapter 4: Chronic rhinosinusitis.

abstract：BACKGROUND:Liquid-based cytology (LBC) has achieved great success in cytological diagnosis of various cancers when compared with conventional smear methods. However, its application in diagnosing nasopharyngeal carcinoma (NPC) has never been studied. METHODS:Eighty-four consecutive patients who underwent nasopharyngea...

journal_title：American journal of rhinology & allergy

authors： Jan YJ,Chen SJ,Wang J,Jiang RS

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Nasal polyposis represents the end point of multiple inflammatory pathways and controversy continues as to the exact roles of medical and surgical approaches in the management of nasal polyposis. METHODS:A combination of both is often required to manage polyps adequately with surgery and intranasal steroids...

journal_title：American journal of rhinology & allergy

authors： Aouad RK,Chiu AG

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Cigarette smoke exposure (CSE) results in extensive inflammation in the upper and lower airways. Reactive oxygen species, such as superoxide, have been shown to be potent mediators of this inflammation. METHODS:Mucosal biopsy specimens were collected from patients undergoing sinonasal surgery and were used ...

journal_title：American journal of rhinology & allergy

authors： Mulligan RM,Atkinson C,Vertegel AA,Reukov V,Schlosser RJ

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Major histocompatibility complex (MHC) class II is involved in T-cell activation, cytokine secretion, and induction of immune responses. Cytokines, staphylococcus super antigens, and eosinophil activation are proposed to play important roles in aspirin-exacerbated respiratory disease (AERD). OBJECTIVES:This...

journal_title：American journal of rhinology & allergy

authors： Esmaeilzadeh H,Nabavi M,Amirzargar AA,Aryan Z,Arshi S,Bemanian MH,Fallahpour M,Mortazavi N,Rezaei N

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:A number of studies suggested that limited economical airborne allergy screening can successfully predict true respiratory allergy and be of use to primary care providers (PCPs) in improving the accuracy of their differential diagnosis and treatment of allergic rhinitis. More accurate diagnosis would lead to...

journal_title：American journal of rhinology & allergy

authors： Mansfield L,Hutteman HR,Tyson S,Enriquez A

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Ginseng (Panax ginseng C.A. Meyer) has been used in Asian countries for the treatment of various diseases. However, the mechanisms of liquid Panax ginseng (LG) on allergic inflammatory response in epidermal growth factor (EGF)-stimulated human airway epithelial cells remain largely unclear. METHODS:MUC5AC, ...

journal_title：American journal of rhinology & allergy

authors： Kim JH,Kang JW,Kim M,Lee DH,Kim H,Choi HS,Kim EJ,Chung IM,Chung IY,Yoon DY

更新日期：2011-03-01 00:00:00

abstract：:Background Retronasal olfaction is important in flavor detection and enjoyment. The ability to identify specific individual retronasal odors may play a role in quality of life for patients with chronic rhinosinusitis (CRS). Objective To identify patterns and improve understanding of retronasal identification of indivi...

journal_title：American journal of rhinology & allergy

authors： Ganjaei KG,Soler ZM,Storck KA,Rowan NR,Othieno FA,Schlosser RJ

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Fibrin glue has been a favorable hydrogel in cartilage tissue engineering, but implantation of chondrocyte-fibrin suspensions have resulted in volume loss. In this study, human septal cartilage chips were seeded onto a fibrin scaffold, and cellular proliferation and production of cartilaginous extracellular ...

journal_title：American journal of rhinology & allergy

authors： Sage A,Chang AA,Schumacher BL,Sah RL,Watson D

更新日期：2009-09-01 00:00:00

abstract：:Chronic rhinosinusitis (CRS) affects 12.5% of the U.S. POPULATION:CRS can be divided into CRS with nasal polyps (CRSwNP) and CRS without nasal polyps. Some individuals with CRSwNP do not respond to standard-of-care medical and surgical management. For these individuals, targeted biologic agents are emerging as an imp...

journal_title：American journal of rhinology & allergy

authors： Chiarella SE,Sy H,Peters AT

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:This study evaluates the safety and efficacy of specific sublingual immunotherapy (SLIT) against grass pollen allergens in patients >60 years of age with seasonal allergic rhinitis (SAR) and/or asthma. This study sought to assess nasal symptoms during the grass pollen season, reduce medication use, and monit...

journal_title：American journal of rhinology & allergy

authors： Bozek A,Kolodziejczyk K,Warkocka-Szoltysek B,Jarzab J

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Standardized allergen-specific immunotherapy (SIT) has been used in China for years. However, there is no extensive study of the safety of standardized SIT in Chinese patients until now. The aim of the current study is to perform a prospective and multicenter study to evaluate the systemic reactions (SRs) of...

journal_title：American journal of rhinology & allergy

authors： Chen J,Li B,Zhao Y,Zhang Q,Wan L,Liu J,Tian X,Li G,Zhou J,Zhang L,Wang P,Cheng Q,Liang J,Zhao P,Luo Z,He J,Lu H,Zhou Y,Zhang Y,Chen X,Pan F,Zhang Z,Zeng L,He B,Zeng Y,Xu X,Kong W

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The nasal tip position and shape is critical to the overall view of the external nose and is significant in planning rhinoplasty procedures. This study was designed to review our experience in nasal tip surgery and to describe our own version of the suture technique in patients having endonasal rhinoplasty....

journal_title：American journal of rhinology & allergy

authors： Cingi C,Songu M

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Acute invasive fungal rhinosinusitis (AIFR) is an aggressive opportunistic infection with a high mortality rate. There are few reports that demonstrate an improvement in the overall prognosis. Furthermore, definite prognostic factors related to patient survival remain unclear. OBJECTIVE:The objective of thi...

journal_title：American journal of rhinology & allergy

authors： Cho HJ,Jang MS,Hong SD,Chung SK,Kim HY,Dhong HJ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The ciliary epithelial cells in the paranasal sinuses produce nasal nitric oxide (NO) continuously and plays a variety of roles in the paranasal sinuses. The purpose of this study was to assess whether we can use the levels of nasal NO (nNO) and exhaled NO (eNO) as a tool for evaluation in chronic rhinosinus...

journal_title：American journal of rhinology & allergy

authors： Jeong JH,Yoo HS,Lee SH,Kim KR,Yoon HJ,Kim SH

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Aspirin-exacerbated respiratory disease (AERD) affects 7% of asthmatics. Usual therapies are inadequate for asthma and/or nasal polyposis, leading to decreased quality of life. OBJECTIVE:Our objective was to evaluate the efficacy of dupilumab in AERD patients with uncontrolled, chronic rhinosinusitis with n...

journal_title：American journal of rhinology & allergy

authors： Mustafa SS,Vadamalai K,Scott B,Ramsey A

更新日期：2020-09-23 00:00:00

abstract：BACKGROUND:This study evaluates if there is any benefit of adding epinephrine to lidocaine in patients undergoing diagnostic rigid nasal endoscopy. A prospective, randomized, double-blinded study was performed. METHODS:Seventy patients were randomized to receive either 2% lidocaine or 2% lidocaine with 0.2% epinephrin...

journal_title：American journal of rhinology & allergy

authors： Al-Qudah M

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to apply protein microarray technology to the study of sinonasal tissue and to identify differential protein expression in nasal polyps from aspirin-sensitive (AS) versus aspirin-tolerant (AT) patients with chronic rhinosinusitis (CRS) and CRS with nasal polyps (CRSwNPs). METHO...

journal_title：American journal of rhinology & allergy

authors： Zander KA,Saavedra MT,West J,Scapa V,Sanders L,Kingdom TT

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Nasal obstruction (NO) is a very common symptom, but its effect on nasal physiology has not been fully understood. We performed this study to determine the effect of severity of NO due to inferior turbinate hypertrophy on airflow pattern using the computational fluid dynamics simulations. METHODS:A three-di...

journal_title：American journal of rhinology & allergy

authors： Lee HP,Poh HJ,Chong FH,Wang de Y

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Nasal congestion and/or obstruction represents a prevalent and extensively studied problem. No published research exists that describes the impact of nasal hair (vibrissae) on nasal obstruction. OBJECTIVE:To assess the impact of nasal vibrissae on subjective and objective measurements of nasal obstruction. ...

journal_title：American journal of rhinology & allergy

authors： Stoddard DG,Pallanch JF,Hamilton GS

更新日期：2015-09-01 00:00:00

abstract：INTRODUCTION:Endoscopic skull base surgery (ESBS) provides a safe, minimally invasive approach to treat benign and malignant skull base lesions. The significance of concomitant sinonasal pathology on imaging in patients undergoing ESBS and its effect on perioperative management is not well described. We sought to ident...

journal_title：American journal of rhinology & allergy

authors： Shah J,Cappello ZJ,Roxbury C,Tang D,Woodard TD,Kshettry VR,Recinos PF,Sindwani R

更新日期：2020-08-11 00:00:00

abstract：OBJECTIVES:Inadvertent intracranial injury from nasogastric tube (NGT) placement is a described and potentially fatal complication following endoscopic transsphenoidal hypophysectomy (TSH). This cadaver study assessed the role of middle turbinate (MT) preservation and medialization in preventing accidental skull base i...

journal_title：American journal of rhinology & allergy

authors： Shah J,Tang D,Grafmiller K,Cappello ZJ,Roxbury C,Sindwani R

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:Activation of adenosine monophosphate-activated protein kinase (AMPK) by metformin, as a master regulator of metabolism, is involved in airway tissue remodeling. Here, we investigated the physical role of AMPK on cell migration, matrix contraction, and the production of matrix metalloproteinases (MMP) in nasal ...

journal_title：American journal of rhinology & allergy

authors： Um JY,Lee SA,Park JH,Shin JM,Park IH,Lee HM

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Increasingly bacterial biofilms have been implicated in chronic rhinosinusitis (CRS), and conventional treatment methods have failed to completely eradicate biofilms. (1) Terminal sialic acids present on sinus mucosal glycoproteins are targets for bacterial adherence and biofilm formation. (2) A subpopulatio...

journal_title：American journal of rhinology & allergy

authors： Tan L,Psaltis A,Baker LM,McGuckin M,Rousseau K,Wormald PJ

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:The extent of surgery required in the management of pediatric non-medial subperiosteal orbital abscess (SPOA) due to medically refractory complicated acute sinusitis is unknown. OBJECTIVES:The primary objective is to compare operative outcomes of children treated with combined endoscopic sinus surgery (ESS)...

journal_title：American journal of rhinology & allergy

authors： Chorney SR,Buzi A,Rizzi MD

更新日期：2020-08-25 00:00:00

abstract：BACKGROUND:Sex hormones are known to have some influence on nasal functions, but their effect on the decongestive response of the nasal mucosa during menstrual cycle is still undetermined. OBJECTIVES:The aim of this study was to examine the nasal physiology, the interconnectedness of olfactory and respiratory nasal fu...

journal_title：American journal of rhinology & allergy

authors： Bogdan MS,Slavic DO,Babovic SS,Zvezdin BS,Kolarov VP,Kljajic VL

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND:One of the major causes of olfactory disturbances is chronic rhinosinusitis (CRS), and the main surgical modality to treat CRS is functional endoscopic sinus surgery (FESS). It, therefore, is essential to assess the effect of this surgery on olfaction. Also, it is necessary to find new ways of measuring olfa...

journal_title：American journal of rhinology & allergy

authors： Gupta D,Gulati A,Singh I,Tekur U

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Laryngeal edema is a life-threatening manifestation of hereditary angioedema (HAE), an autosomal-dominant disorder caused by quantitative or functional C1 esterase inhibitor (C1 INH) deficiency. The preparation of nanofiltered C1 INH (C1 INH-nf) used in this study is indicated for routine prophylaxis against...

journal_title：American journal of rhinology & allergy

authors： Riedl MA,Lumry WR,Li HH,Craig TJ,Fitts D,Kalfus I,Uknis ME

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Volumetric analysis of the olfactory cleft by using computed tomography has been associated with olfaction in patients with chronic rhinosinusitis (CRS). However, existing studies have not comprehensively measured olfaction, and it thus remains unknown whether correlations differ across specific dimensions o...

journal_title：American journal of rhinology & allergy

authors： Kohli P,Schlosser RJ,Storck K,Soler ZM

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Allergen immunotherapy (AIT) has been in practice for more than 100 years. However, research in novel routes and delivery methods of immunotherapy to treat allergic rhinitis (AR) and conjunctivitis has only recently occurred in the United States, where the predominant form of AIT provided is largely via a su...

journal_title：American journal of rhinology & allergy

authors： Lee S,Nolte H,Benninger MS

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The treatment of chronic rhinosinusitis (CRS) often requires chronic or intermittent oral steroid therapy, which has the potential for adverse skeletal effects, including osteoporosis and increased risk of fragility fractures. The purpose of this study was to determine the prevalence of osteopenia/osteoporos...

journal_title：American journal of rhinology & allergy

authors： Rajasekaran K,Seth R,Abelson A,Batra PS

更新日期：2010-05-01 00:00:00