Does neoadjuvant chemotherapy impair long-term survival for ovarian cancer patients? A nationwide Danish study.

abstract：INTRODUCTION:Focused ultrasound under real-time MR guidance and control (MRgFUS) can be used for the thermal ablation of tissue. Currently this technique is used clinically for the noninvasive treatment of uterine leiomyomas and is in clinical evaluation for breast cancer, adenomyosis and other indications. MRgFUS is b...

journal_title：Gynecologic oncology

authors： Machtinger R,Inbar Y,Ben-Baruch G,Korach J,Rabinovici J

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:To assess the utility of tumor diameter (TD) for predicting lymphatic dissemination (LD) and determining need for lymphadenectomy following diagnosis of endometrioid endometrial cancer. METHODS:Patients diagnosed with stage I-III endometrioid endometrial cancer during 2003-2013 who underwent pelvic or para-...

journal_title：Gynecologic oncology

authors： Cox Bauer CM,Greer DM,Kram JJF,Kamelle SA

更新日期：2016-05-01 00:00:00

abstract：:In approximately ten months' time, the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected over 34 million people and caused over one million deaths worldwide. The impact of this virus on our health, relationships, and careers is difficult to overstate. As the economic realiti...

journal_title：Gynecologic oncology

authors： Ferriss JS,Rose S,Rungruang B,Urban R,Spencer R,Uppal S,Sinno AK,Duska L,Walsh C

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:Cone margin status has been reported to be the most important predictor of residual disease in patients with cervical intraepithelial neoplasia (CIN) undergoing electrosurgical excisional treatment. The primary aim of this study of patients treated with electrosurgical conization was to evaluate the associati...

journal_title：Gynecologic oncology

authors： Costa S,De Nuzzo M,Infante FE,Bonavita B,Marinelli M,Rubino A,Rambelli V,Santini D,Cristiani P,Bucchi L

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:MDM2 is an important negative regulator of the p53 tumor suppressor protein. A naturally occurring T/G single nucleotide polymorphism (SNP) in the MDM2 gene promoter, SNP309, causes an increase in MDM2 protein levels and impairment of p53 tumor suppressor activity. SNP309 occurs at a relatively high frequenc...

journal_title：Gynecologic oncology

authors： Walsh CS,Miller CW,Karlan BY,Koeffler HP

更新日期：2007-03-01 00:00:00

abstract：:Sixty-eight patients with FIGO stage I, grade 2 or 3 adenocarcinoma of the endometrium were treated according to a protocol involving 10 Gy external pelvic irradiation, prompt hysterectomy with surgical staging, and postoperative therapy individualized according to surgical-pathologic findings. Five-year survival for ...

journal_title：Gynecologic oncology

authors： Shimm DS,Wang CC,Fuller AF Jr,Nelson JH Jr,Nikrui N,Young RH,Scully RE

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVES:The effect on progesterone and estrogen receptor expression in glands and stroma after two different treatment regimens of endometrial hyperplasia was determined. METHODS:Pre- and post-treatment paraffin-embedded endometrial hyperplasia specimens from women treated with levonorgestrel (LNG) intrauterine dev...

journal_title：Gynecologic oncology

authors： Vereide AB,Kaino T,Sager G,Arnes M,Ørbo A

更新日期：2006-05-01 00:00:00

abstract：:To determine how patients with invasive cervical cancer present and whether presentation affects disease-free survival (DFS), a review of 81 patients treated for cervical cancer by the Division of Gynecologic Oncology and Pelvic Surgery at the Southern California Permanente Medical Group between January 1, 1986, and D...

journal_title：Gynecologic oncology

authors： Pretorius R,Semrad N,Watring W,Fotheringham N

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Microglandular adenocarcinoma is a rare type of endometrium carcinoma and had some potential diagnostic problems with difficulties in discriminating from some malign and benign lesions of cervix. CASE REPORT:A 70-year-old woman misdiagnosed as cervical adenocarcinoma was referred to our clinic, and the lesi...

journal_title：Gynecologic oncology

authors： Karateke A,Haliloglu B,Atay V,Gurbuz A,Kir G

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the contribution of molecular subtype to 30-day postoperative complications and 90-day mortality after primary debulking surgery (PDS) in advanced stage high-grade serous ovarian cancer (HGSOC). METHODS:Patients with stages III-IV HGSOC undergoing PDS from 1994 to 2011 with available molecular su...

journal_title：Gynecologic oncology

authors： Torres D,Kumar A,Bakkum-Gamez JN,Weaver AL,McGree ME,Wang C,Langstraat CL,Cliby WA

更新日期：2019-02-01 00:00:00

abstract：:Twenty-nine patients with recurrent advanced stage ovarian cancer were treated with 5-fluorouracil (5-FU) and leucovorin by intravenous bolus on 5 consecutive days, repeated every 3 weeks. Twenty-one of these patients had experienced disease progression while receiving a cisplatin- or carboplatin-based regimen. There ...

journal_title：Gynecologic oncology

authors： Reed E,Jacob J,Ozols RF,Young RC,Allegra C

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:To compare the efficacy of chemotherapy (C) combined with bevacizumab (Bev) versus Bev alone in recurrent, heavily pretreated epithelial ovarian cancer (EOC). METHODS:A multicenter analysis of patients treated from 2004 to 2011 was performed. Demographic, treatment, response, and adverse event information w...

journal_title：Gynecologic oncology

authors： Fuh KC,Secord AA,Bevis KS,Huh W,ElNaggar A,Blansit K,Previs R,Tillmanns T,Kapp DS,Chan JK

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the hospital and patient factors associated with robotic surgery for endometrial cancer in the United States. METHODS:Data was obtained from the Nationwide Inpatient Sample from the year 2010. Chi-squared and multivariate analyses were used for statistical analysis. RESULTS:Of the 6560 endometri...

journal_title：Gynecologic oncology

authors： Chan JK,Gardner AB,Taylor K,Blansit K,Thompson CA,Brooks R,Yu X,Kapp DS

更新日期：2015-07-01 00:00:00

abstract：:A patient with Stage IIB squamous cell cancer of the cervix presented 10 days into her primary radiation therapy with neutropenic fever and diarrhea requiring hospitalization and delay in treatment. The patient's history revealed extensive use of alternative therapies including potential toxic botanicals. This case ra...

journal_title：Gynecologic oncology

authors： von Gruenigen VE,Hopkins MP

更新日期：2000-04-01 00:00:00

abstract：:Less extensive surgical treatment has become possible for limited vulvar cancer. However, primary closure is advisable only when the defect is minimal and tissue replacement is always needed in radical excisions. Local flaps are always considered the first choice because of their characteristics of similarity to the r...

journal_title：Gynecologic oncology

authors： Tateo A,Tateo S,Bernasconi C,Zara C

更新日期：1996-08-01 00:00:00

abstract：:We have previously reported that simple hysterectomy is adequate therapy for microinvasive carcinoma of the cervix with less than 3 mm stromal invasion (Yajima, A., et al, Am. J. Obstet. Gynecol. 135, 685-688, 1979). However, whether it is possible to effectively treat patients with deeper stromal invasion remained in...

journal_title：Gynecologic oncology

authors： Yaegashi N,Sato S,Inoue Y,Noda K,Yajima A

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVES:Fixed-dose rate gemcitabine plus docetaxel is active as second-line therapy for metastatic uterine leiomyosarcoma. We sought to determine the activity of this regimen as first-line treatment. METHODS:Eligible women with advanced uterine leiomyosarcoma were treated with gemcitabine 900 mg/m(2) over 90 min, o...

journal_title：Gynecologic oncology

authors： Hensley ML,Blessing JA,Mannel R,Rose PG

更新日期：2008-06-01 00:00:00

abstract：:Forty-one eligible patients with metastatic or recurrent carcinoma of the uterine cervix received 149 courses of carboplatin. The drug was administered at a starting dosage of 400 mg/m2 IV every 28 days. The overall response rate was 15% (two complete responses, four partial responses; 95% confidence interval 6-29%) a...

journal_title：Gynecologic oncology

authors： Weiss GR,Green S,Hannigan EV,Boutselis JG,Surwit EA,Wallace DL,Alberts DS

更新日期：1990-12-01 00:00:00

abstract：OBJECTIVE:Younger patients with invasive epithelial ovarian cancer (EOC) frequently want to preserve their fertility, but the role of fertility-sparing surgery in EOC has not been well defined. We therefore assessed tumor recurrence, patient survival and pregnancy outcomes in patients with invasive EOC who underwent fe...

journal_title：Gynecologic oncology

authors： Park JY,Kim DY,Suh DS,Kim JH,Kim YM,Kim YT,Nam JH

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Primary vaginal adenosarcomas are extremely rare, and typical adenosarcomas are of low malignancy. However, aggressive forms with sarcomatous overgrowth have been reported, those appear to have a poor prognosis. CASE:A 52-year-old woman who had undergone prior surgery for uterine leiomyoma and an ovarian cy...

journal_title：Gynecologic oncology

authors： Toyoshima M,Akahira J,Moriya T,Hayakawa S,Yaegashi N

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Yolk sac tumors of the ovary are generally very responsive to chemotherapy; however, they are difficult to manage in the setting of platinum resistance where treatment options are limited and outcomes are poorer. CASE:We present a 39-year-old woman who had a platinum-resistant yolk sac ovarian tumor. She ac...

journal_title：Gynecologic oncology

authors： Jeyakumar A,Chalas E,Hindenburg A

更新日期：2001-09-01 00:00:00

abstract：:Of a group of 68 patients treated with standard polychemotherapy (CAP-5), 52 were evaluated by an early second-look laparotomy, preferably after three cycles of treatment. Of 21 patients with initial tumor residuals smaller than 2 cm, only 5 had residual tumor, and of 31 patients with tumor larger than 2 cm, 27 had re...

journal_title：Gynecologic oncology

authors： van Lith JM,Bouma J,Aalders JG,Boonstra H,Sleijfer DT,Willemse PH

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVE:To evaluate safety, tolerability, and antitumor activity of pembrolizumab monotherapy in patients with programmed death ligand 1 (PD-L1)-expressing advanced ovarian cancer enrolled in the multicohort, phase Ib KEYNOTE-028 trial. METHODS:Key inclusion criteria were age ≥18 years; advanced ovarian epithelial, ...

journal_title：Gynecologic oncology

authors： Varga A,Piha-Paul S,Ott PA,Mehnert JM,Berton-Rigaud D,Morosky A,Yang P,Ruman J,Matei D

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:To report the intermediate-term results of trans-abdominal ultrasound (TAUS)-guided brachytherapy in cervical cancer. MATERIALS AND METHODS:Ninety-two patients with cervical cancer (stage IB-IVA, according to FIGO staging), were treated by curative radiotherapy from February 2012 to June 2015. All patients ...

journal_title：Gynecologic oncology

authors： Tharavichitkul E,Chakrabandhu S,Klunklin P,Onchan W,Jia-Mahasap B,Wanwilairat S,Tippanya D,Jayasvasti R,Sripan P,Galalae RM,Chitapanarux I

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate clinical manifestations, management options, and prognosis for women presenting with gestational trophoblastic tumors with vaginal metastasis. METHOD:Fifty-one patients with vaginal metastases were analyzed retrospectively between January 1985 and September 2000. Vaginal...

journal_title：Gynecologic oncology

authors： Yingna S,Yang X,Xiuyu Y,Hongzhao S

更新日期：2002-03-01 00:00:00

abstract：PURPOSE:To examine the differentially expressed cancer-related genes in two morphologically different uterine cervical carcinoma cell lines derived from the same patient by an Affymetrix Human Cancer G110 Array carrying 1700 cancer-associated genes. In addition, to investigate specific gene expression depending on hist...

journal_title：Gynecologic oncology

authors： Fujimoto T,Nishikawa A,Iwasaki M,Akutagawa N,Teramoto M,Kudo R

更新日期：2004-05-01 00:00:00

abstract：:This article describes the first reported case of a primary transitional cell carcinoma of the renal pelvis metastatic to the ovary. The clinical presentation in our patient was similar to that of a primary ovarian carcinoma. The differential diagnosis of a primary or metastatic transitional cell carcinoma in the ovar...

journal_title：Gynecologic oncology

authors： Hsiu JG,Kemp GM,Singer GA,Rawls WH,Siddiky MA

更新日期：1991-05-01 00:00:00

abstract：:Ovarian management at the time of radical hysterectomy for cervical cancer was reviewed retrospectively over a 7-year period. All patients had early-stage cancer except three who had stage IIB disease. Approximately 80% of patients had squamous cancer and 20% adenocarcinoma or adenosquamous carcinoma. The mean age was...

journal_title：Gynecologic oncology

authors： Owens S,Roberts WS,Fiorica JV,Hoffman MS,LaPolla JP,Cavanagh D

更新日期：1989-12-01 00:00:00

abstract：OBJECTIVE:Timely surgery has been shown to impact outcome in endometrial cancer patients. Social determinants of health (SDH) are associated with adverse cancer outcomes. We sought to evaluate the association of SDH with surgical treatment indicators in endometrial cancer patients in a public healthcare system. METHOD...

journal_title：Gynecologic oncology

authors： Helpman L,Pond GR,Elit L,Anderson LN,Seow H

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To estimate the frequency of cervical cytologic/histologic discrepancies in a group of obstetric patients diagnosed as HIV infected by routine prenatal screening. Also, to determine if serum CD4 levels or sexually transmitted diseases (STDs) are associated with the occurrence of preinvasive cervical disease i...

journal_title：Gynecologic oncology

authors： Robinson WR,Barnes SE,Adams S,Perrin MS

更新日期：1997-06-01 00:00:00