Abstract:
:An hypothesis is presented to explain the link between acquired immunodeficiency syndrome (AIDS) and Kaposi's sarcoma (KS). According to this hypothesis, AIDS involves all four components of the integrated lymphatic system--lymphatics, lymph nodes, lymphocytes, and lymph--and thereby resembles various congenital and acquired lymphologic syndromes characterized by one or more of the following features: lymphostasis, angiogenesis, and fibrosis; depletion of immunocompetent cells and immunosuppression; opportunistic infections; and vascular neoplasms. A better understanding of the steps in the evolution of these processes and their interrelationships to the four components of the lymphatic system should provide insight into the immunopathogenesis of AIDS-KS as well as its detection and treatment.
journal_name
Lymphologyjournal_title
Lymphologyauthors
Witte MH,Witte CLsubject
Has Abstractpub_date
1988-03-01 00:00:00pages
4-10issue
1eissn
0024-7766issn
2522-7963journal_volume
21pub_type
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