From childhood onset lymphedema to fatal fetal hydrops: Possible modifying genes for a FOXC2 mutation.

Abstract:

:We performed whole exome sequencing in a family with FOXC2 mutation where the phenotype in one generation was strikingly more severe. Although there were 3 mutations shared by 2 fatal fetal hydrops cases and not the mildly affected mother, none of them were likely to be the cause of the marked phenotypic change.

journal_name

Lymphology

journal_title

Lymphology

authors

Lai LW,Erickson RP,Bernas M,Witte MH

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

85-88

issue

2

eissn

0024-7766

issn

2522-7963

journal_volume

51

pub_type

杂志文章
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    authors: Baulieu F,Baulieu JL,Alison D,Barsotti J,Itti R

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  • Culture of smooth muscle cells from guinea pig mesenteric lymphatic vessels.

    abstract::The in vitro culture of lymphatic smooth muscle cells (SMCs) is a crucial step in studying their function and involvement in disease. Yet there is no efficient approach available so far because of the difficulties posed by the small size of most lymphatic vessels. We present a simple yet efficient method for isolating...

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    authors: Wang DG,Liu ZY,Bi YS,Sun SZ,Shi L,Wang X,Zhang XH

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  • Surgical treatment of scrotal lymphedema: modified surgical technique.

    abstract::Lymphedema is a chronic disease in which lymph accumulates under the subcutaneous tissue. The condition may be due to either congenital or acquired lymphatic system abnormalities. Genital lymphedema (scrotal lymphedema) has a high psychological and functional impact, and many surgical techniques have been tried in an ...

    journal_title:Lymphology

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    doi:

    authors: Atta A,Saber El Basiouny M,Mostafa Abass S

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  • Immune proteins and other biochemical constituents of peripheral lymph in patients with malignancy and postirradiation lymphedema.

    abstract::Concentration of immunoglobulins and complement proteins were studied in a group of 33 patients with localized tumors and lymphoproliferative disorders. Generally, low levels have been found, in many cases below the lowest limit of the control group. The reductions in concentration were more pronounced in patients wit...

    journal_title:Lymphology

    pub_type: 杂志文章

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    authors: Olszewski WL,Loe K,Engeset A

    更新日期:1978-12-01 00:00:00

  • Adventitial lymphatics and atherosclerosis.

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    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Drozdz K,Janczak D,Dziegiel P,Podhorska M,Piotrowska A,Patrzalek D,Andrzejak R,Szuba A

    更新日期:2012-03-01 00:00:00

  • Lymphography of the edematous extremities.

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    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Akisada M

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  • Who discovered the lymphatic system.

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    journal_title:Lymphology

    pub_type: 历史文章,杂志文章

    doi:

    authors: Chikly B

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  • Bronchovascular cuff formation and lung lymph flow in edema formation of anesthetized sheep.

    abstract::The relationship between bronchovascular cuff formation and lung lymph flow in hydrostatic edema was evaluated. After a balloon was inserted into the left atrium to increase left atrial pressure for 5 hrs, peripheral lung tissues were resected for analysis of the wet-dry ratio and cuff formation. The degree of cuff fo...

    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Naito T,Ozawa Y,Tomoyasu M,Inagaki M,Fukue M,Goto Y,Sakai M,Yamamoto T,Ishikawa S,Onizuka M

    更新日期:2009-09-01 00:00:00

  • A preliminary note on the composition of lymphocytes in human peripheral lymph.

    abstract::Pilot experiments on the composition of lymphocytes in human peripheral lymph, mainly from healthy human volunteers, are presented. The experiments undertaken so far show a reduced proportion of B cells and an increased proportion of "Ia" positive lymphocytes in peripheral lymph as compared to peripheral blood. If con...

    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Godal T,Engeset A

    更新日期:1978-12-01 00:00:00

  • Effect of tumor necrosis factor-alpha and interleukin-2 on spleen lymphocyte migration in mouse skin.

    abstract::Tumor necrosis factor-alpha (TNF-alpha) and interleukin-2 (IL-2) are reported to enhance lymphocyte binding to endothelial cells in vitro. We examined these two agents on lymphocyte migration in vivo. Spleen lymphocytes were radiolabeled with tritiated uridine (3H-UR) and then injected i.v. into mice. Each cytokine (T...

    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Sun J,Liu Z,Bi Y,Guo Z,Hua T,Ding Z

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  • Enzyme-histochemical staining of dermal lymphatic capillaries by guanylate cyclase.

    abstract::Human foreskins were examined for enzyme-histochemical staining of microvessels using guanylate cyclase, an enzyme similar to adenylate cyclase. Like 5'-nucleotidase (which hydrolyzes 5'-adenosine monophosphate to adenosine), and adenylate cyclase (which converts adenosine triphosphate to cyclic AMP), guanylate cyclas...

    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Nishida S,Ohkuma M

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  • Self-reported information sources and perceived knowledge in individuals with lymphedema.

    abstract::Currently, a limited number of studies have been conducted that examine sources of information and knowledge level in individuals with lymphedema. This study aimed (1) to examine self-reported information sources and perceived lymphedema knowledge among individuals with lymphedema; and (2) to examine differences in se...

    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Deng J,Fu MR,Armer JM,Cormier JN,Radina E,Thiadens SR,Dietrich MS,Weiss J,Tuppo CM,Ridner SH

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  • The lymphatic drainage of the left ventricle in the Yucatan minipig.

    abstract::The gross anatomy of the cardiac lymphatic system draining the left ventricle was studied in 15 Yucatan minipigs and 2 regular swine. The findings confirm that the drainage pathways are similar to those of man and dog. After a coloring marker is injected near the apex of the left ventricle, one or more lymphatics are ...

    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Palmer AS,Miller AJ,Greene R

    更新日期:1998-03-01 00:00:00

  • Surgical exploration of the abdominal lymphatic system in patients with malignancies.

    abstract::In the management of selected patient with malignant diseases, laparotomy can be useful for determining the anatomic extent of disease in order to individualize appropriate intensive treatment. The decision to subject a patient to a staging laparotomy requires joint decisions by surgeons, radiation therapists, chemoth...

    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Glatstein E

    更新日期:1977-06-01 00:00:00

  • Lymphatic aneurysm of the heart.

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    journal_title:Lymphology

    pub_type: 杂志文章

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    authors: Lupinski RW

    更新日期:2004-09-01 00:00:00

  • Experimental study on lymphatic vascular changes in the development of cancer.

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    journal_title:Lymphology

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    authors: Tanigawa N,Kanazawa T,Satomura K,Hikasa Y,Hashida M,Muranishi S,Sezaki H

    更新日期:1981-12-01 00:00:00

  • Abdominal lymph flow response to intraperitoneal fluid in awake sheep.

    abstract::Lymphatic vessels are important in draining excess fluid from the abdominal space and preventing ascites. In sheep, diaphragmatic lymph vessels draining the abdominal space run to the caudal mediastinal lymph node and efferent vessels from the node drain into veins in the neck. To estimate the lymph flow response to e...

    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Drake RE,Gabel JC

    更新日期:1991-06-01 00:00:00

  • Benign supraclavicular tumorous lymphangiectasia--a new disease?

    abstract::We describe an isolated recurrent non-inflammatory tumorous swelling of the supraclavicular fossa in four premenopausal women. Ultrasonography, magnetic resonance imaging and computer tomography of the neck each suggested an inhomogeneous mass consistent with "lymphangioma." In each patient the clinical course and his...

    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Preyer S,Kaiserling E,Heinle H,Földi E,Zenner HP,Földi M

    更新日期:1995-09-01 00:00:00

  • REPEATED INTRANODAL LYMPHANGIOGRAPHY FOR THE TREATMENT OF LYMPHATIC LEAKAGE.

    abstract::Treatment of patients with chylous or non-chylous lymphatic leakage can be difficult. An approach using therapeutic lymphangiography can reduce the lymphatic leakage, but it seldom stops the leakage immediately and subsequent conservative treatment is necessary. We report three cases in which intranodal lymphangiograp...

    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Kariya S,Nakatani M,Yoshida R,Ueno Y,Komemushi A,Tanigawa N

    更新日期:2015-06-01 00:00:00

  • Alterations of untreated lymphedema and it's grades over time.

    abstract::Lymphedema is assumed to increase in amount and Grade with time. This work verifies that assumption, and may be helpful in persuading patients to undergo treatment and provides prognosis for likelihood of future disability. Before-treatment volumes of lymphedema/normal, Grades and durations' are compared in 231 postma...

    journal_title:Lymphology

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    doi:

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  • Modulation of mouse spleen natural killer (NK) cell activity by beta-interferon, interleukin-1, and prostaglandins.

    abstract::By using CBA/J mice as a source of effector cells and Yac-1 lymphoma line as "target" cells, the natural killer (NK) cell activity was assayed following both in vivo and in vitro immunomodulation [beta-interferon (IF), interleukin-1 (IL-1), indomethacin (IND), prostaglandin-E2 (PGE)]. Only IF/IND and IL-1/IND mixed in...

    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Voiculescu CL,Rosu L,Rogoz S

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  • Arteriovenous shunts in peripheral lymphedema: hemodynamic features and isotopic visualization.

    abstract::The hemodynamic characteristics of peripheral lymphedema were studied in 28 patients with uni- or bilateral leg swelling. Leg blood flow was measured by venous isotope dilution (a technique for nutritive--capillary blood flow) and arteriovenous shunts were visualized by perfusion scintigraphy using radiolabelled macro...

    journal_title:Lymphology

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    authors: Solti F,Iskum M,Banos C,Salamon F

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  • Fibrosclerotic lymphedema: pathophysiology and therapy.

    abstract::We describe our experience with 12 patients with severe fibrotic lymphedema treated between 1979 and 1987. Each patient initially underwent nonoperative treatment (postural drainage and pneumatic compression) and in 10 patients who required operation, these measures were continued postoperatively. Operation included e...

    journal_title:Lymphology

    pub_type: 杂志文章

    doi:

    authors: Talarico F,Brunetto D,Scialabba M,Pernice I,Valenti G,Benvegna S,Mastrandrea G,Rusignuolo F

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  • Syndromic classification of hereditary lymphedema.

    abstract::Since the late 1800's, the familial occurrence of peripheral lymphedema has been well-documented in Milroy and Meige syndromes. However, the presence of lymphedema in many other hereditary dysmorphic syndromes has not been fully appreciated. In order to establish more standardized and detailed clinical phenotypic crit...

    journal_title:Lymphology

    pub_type: 杂志文章,评审

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  • Massive localized lipolymphedema pseudotumor in a morbidly obese patient.

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  • AIDS-Kaposi's sarcoma complex: evolution of a full-blown lymphologic syndrome.

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  • The Diagnosis and Treatment of Peripheral Lymphedema: 2016 Consensus Document of the International Society of Lymphology.

    abstract::This International Society of Lymphology (ISL) Consensus Document is the latest revision of the 1995 Document for the evaluation and management of peripheral lymphedema (1). It is based upon modifications: [A] suggested and published following the 1997 XVI International Congress of Lymphology (ICL) in Madrid, Spain (2...

    journal_title:Lymphology

    pub_type: 杂志文章,实务指引

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  • Effects of lymph stasis on healing of rat intestinal anastomosis.

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    authors: De Franco S,Gelmetti M,Lampugnani R,Gamrielli M

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  • The energetics of lymph formation.

    abstract::A very important unanswered problem is the source of the energy required for formation of lymph. The most widely held theory has been that fluid filters from the capillaries, flows through the tissues, and then enters the lymphatic as a result of a continuous positive pressure gradient from the blood capillary to the ...

    journal_title:Lymphology

    pub_type: 杂志文章,评审

    doi:

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  • Differential expression of collagens type I and type IV in lymphangiogenesis during the angiogenic process associated with bleomycin-induced pulmonary fibrosis in rat.

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    doi:

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