Abstract：
:Elevated levels of maternal serum alpha-fetoprotein (MSAFP) will identify a population at increased risk for specific congenital malformations, which are accurately diagnosed by amniotic fluid AFP and acetylcholinesterase. The risk for spontaneous abortion related to amniocentesis, combined with increasing confidence in the accuracy of ultrasound diagnosis, has caused us to question the need for amniocentesis in the diagnostic workup of pregnancies complicated by elevated levels of AFP in maternal serum. A retrospective study of 257 pregnancies evaluated for elevated serum AFP levels revealed 16 fetal malformations diagnosed by amniotic fluid AFP and acetylcholinesterase. Only 12 of these malformations were diagnosed on the initial ultrasound study. All malformations were diagnosed when ultrasound examination was repeated for increased acetylcholinesterase activity. Earlier gestational age at scanning, smaller defects, and pure technical failure were implicated as causes of misdiagnosis. The rate of fetal malformations identified in this high-risk population (6.23%) and the rate of ultrasound misdiagnosis (1.5% of the population with elevated levels of MSAFP) imply that amniocentesis should still be considered an essential part of the diagnostic workup in these situations.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Drugan A,Zador IE,Syner FN,Sokol RJ,Sacks AJ,Evans MIsubject
Has Abstractpub_date
1988-10-01 00:00:00pages
627-30issue
4eissn
0029-7844issn
1873-233Xjournal_volume
72pub_type
杂志文章abstract：:A light microscopic, an electron microscopic, and a ultrahistochemical study have been made of seven placentas from women with mild and excellently controlled chemical gestational diabetes. Only one placenta showed no significant abnormality; the remainder showed, to a varying degree, changes in the syncytiotrophoblas...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：OBJECTIVE:To compare the diagnostic and prognostic performance of maternal blood C-reactive protein, white blood cell count (WBC), and temperature with that of amniotic fluid (AF) WBC in preterm labor. METHODS:One hundred two women with preterm labor and intact membranes were studied. Maternal blood was collected to m...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0029-7844(95)00380-0
更新日期：1996-02-01 00:00:00
abstract：OBJECTIVE:To prospectively compare the Protein C Global assay results in a cohort of infertile women who conceived after assisted reproductive technology (ART) with results from women who conceived spontaneously. METHODS:Sixty-four infertile women who conceived after ART and 47 fertile women who conceived spontaneousl...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e3181db67f3
更新日期：2010-05-01 00:00:00
abstract：:The issue of race and ethnicity within obstetrics and gynecology has come to the forefront in the current social and political climate. Understanding the ill effects of racism within the clinical space requires an acknowledgment of both the ongoing problem and current limitations in the state of knowledge and praxis a...
journal_title：Obstetrics and gynecology
pub_type： 社论
doi：10.1097/AOG.0000000000002868
更新日期：2018-10-01 00:00:00
abstract：:Forty-eight of 100 pregnant women received a 100-g (nonfasting) glucose screening test at about 28 weeks' gestation, followed by a 100-g glucose tolerance test. Another 52 received a 100-g (nonfasting) glucose polymer screening test followed by a 100-g glucose polymer tolerance test. Mean plasma glucose one hour after...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：
更新日期：1985-10-01 00:00:00
abstract：:Preterm birth is the leading cause of neonatal mortality and a substantial portion of all birth-related short- and long-term morbidity. Spontaneous preterm labor is responsible for more than half of preterm births. Its management is the topic of this review. Although there are many maternal characteristics associated ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/s0029-7844(02)02212-3
更新日期：2002-11-01 00:00:00
abstract：OBJECTIVE:To define the frequency, risk factors, and outcomes of massive transfusion in obstetrics. METHODS:The State Inpatient Dataset for New York (1998-2007) was used to identify all delivery hospitalizations for hospitals that reported at least one delivery-related transfusion per year. Multivariable logistic regr...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000000021
更新日期：2013-12-01 00:00:00
abstract：:Predictors of postpartum endometritis were identified in 607 asymptomatic, laboring women. One hundred (16.5%) developed postpartum endometritis. Multivariate analysis using stepwise logistic regression identified cesarean delivery (relative risk 12.8; P less than .0001) as the dominant overall predictor. In patients ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：:Previous reports have implicated the Dalkon shield intrauterine device (IUD) in septic second trimester abortion and maternal death from sepsis. In the case reported here, Fusobacterium necrophorum, a rarely pathogenic vaginal anaerobe, gained access to the uterus in a woman wearing a Dalkon shield and caused acute pa...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1981-09-01 00:00:00
abstract：BACKGROUND:Uterine malignant mixed mesodermal tumor is a rare variant of uterine cancer. Data suggest that tamoxifen is involved in the pathogenesis. We report a case of a women in whom a malignant mixed mesodermal tumor was diagnosed while she was taking raloxifene, which is also a selective estrogen receptor modulato...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000160480.55365.a8
更新日期：2005-05-01 00:00:00
abstract：:This study was planned to determine the effects of estrogen and progestogen on female sexual behavior. Forty-nine women who had undergone hysterectomy and bilateral salpingo-oophorectomy took part in a double-blind placebo-controlled cross-over study. Over a 12-month period each woman received 3 months each of ethinyl...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1980-09-01 00:00:00
abstract：:Heavy menstrual bleeding is defined as excessive menstrual blood loss that interferes with a woman's physical, social, emotional, or material quality of life. If obstetrician-gynecologists suspect that a patient has a bleeding disorder, they should work in coordination with a hematologist for laboratory evaluation and...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003412
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To assess long-term clinical and urodynamic outcomes of suburethral sling procedures using polytetrafluoroethylene grafts. METHODS:Between January 1986 and May 1991, 108 women underwent suburethral sling placement to treat genuine stress incontinence. At least 1 year after surgery, 62 women participated in a...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：10.1016/0029-7844(95)00098-C
更新日期：1995-07-01 00:00:00
abstract：:Non-Hodgkin lymphoma was diagnosed initially in a curettage specimen of a puerperal uterus 3 weeks after normal delivery of a healthy infant. The disease, which probably existed during the last trimester of pregnancy, was classified as clinical stage IVb. Combination chemotherapy resulted in immediate improvement and ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：OBJECTIVE:To assess the effect of variables that influence the pregnancy outcome of intrauterine insemination with frozen donor sperm. METHODS:A retrospective analysis of 408 cycles of frozen donor sperm inseminations were studied. Cycle fecundity and cumulative probability of pregnancy were compared according to seve...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0029-7844(96)00074-9
更新日期：1996-07-01 00:00:00
abstract：OBJECTIVE:To describe obstetric health care providers' responses and counseling approaches to patients' disclosures of marijuana use during first prenatal visits. METHODS:We performed a content analysis of audio-recorded patient-health care provider first prenatal visits for obstetrics health care providers' responses...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001343
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVE:To estimate the influence of adequacy of prenatal care and other known risk factors on the risk of repeating low birth weight (LBW) (less than 2500 g). METHODS:This was a retrospective cohort study of women having two births in Washington state during 1984-1990, as recorded using linked birth certificate rec...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：:Magnetic resonance imaging is a new noninvasive diagnostic technique that involves no ionizing radiation, has no known significant adverse biologic effects, and produces high resolution cross-sectional body images. When compared with sonography and x-ray computed axial tomography, magnetic resonance imaging may have s...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1985-11-01 00:00:00
abstract：:Insulin-dependent diabetic women without adequate glucose control have a higher spontaneous abortion rate when compared with the general population. The present study examined whether the increased rate of spontaneous abortions in insulin-dependent diabetic women was associated with poor glycemic control in the early ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-198609000-00015
更新日期：1986-09-01 00:00:00
abstract：:To determine whether amnio-polymerase chain reaction (amnio-PCR) can replace conventional cytogenetic study for confirming the karyotype of fetuses in women with positive biochemical screening for fetal Down syndrome. To check the accuracy of this technique in our laboratory, we first compared the amnio-PCR results wi...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(03)00222-9
更新日期：2003-05-01 00:00:00
abstract：OBJECTIVE:To determine the relationships among the pregnancy outcomes of growth-retarded fetuses, Doppler flow velocimetry of the fetomaternal circulation, and pathologic changes in the placenta. METHODS:Forty-seven fetuses confirmed to be growth-retarded by ultrasonographic biometry were monitored during pregnancy in...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1993-10-01 00:00:00
abstract：:The Acyclovir in Pregnancy Registry was established to gather data on prenatal exposure to acyclovir. Exposed pregnancies are tracked prospectively to ascertain exposure, risk factors, and pregnancy outcome. Through June 30, 1990, 312 acyclovir-exposed pregnancies had been reported and followed. Of these, 239 were exp...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：BACKGROUND:The single-incision midurethral sling has been introduced as an alternative to the traditional midurethral sling. Complications have been reported rarely. CASE:A 57-year-old multiparous woman with history of osteogenesis imperfecta type I underwent single-incision midurethral sling placement for stress urin...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e3182431951
更新日期：2012-02-01 00:00:00
abstract：:Although not all multifetal pregnancies occur after the use of assisted reproductive technology, fertility treatments have contributed significantly to the increase in multifetal pregnancies. In almost all cases, it is preferable to avoid the risk of higher-order multifetal pregnancy by limiting the number of embryos ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,实务指引
doi：10.1097/AOG.0000000000002302
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVE:To test the hypothesis that fetal growth restriction (FGR) associated with a maternal hypertensive disorder results in worse perinatal outcome than FGR in pregnancies without maternal hypertension. METHODS:All consecutive, singleton, nondiabetic, small for gestational age (SGA) deliveries (birth weight at or...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0029-7844(96)02169-2
更新日期：1996-08-01 00:00:00
abstract：:Two hundred ninety-four women with cervical intraepithelial neoplasia were treated once with either cryotherapy or laser vaporization. Treatment results were controlled for grade, size, and distribution of cervical intraepithelial neoplasia. Cervical intraepithelial neoplasia measuring less than 3 cm in diameter witho...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1985-12-01 00:00:00
abstract：BACKGROUND:Traditional methods of exchange of research information may not be rapid enough, especially for international multicenter studies or when discussing controversial issues such as the value of fetal monitoring. The Internet is a useful tool that provides numerous opportunities for immediate communication withi...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(99)00569-4
更新日期：2000-02-01 00:00:00
abstract：OBJECTIVE:To determine whether maternal midtrimester serum N-terminal peptide of proatrial natriuretic peptide, free beta subunit of human chorionic gonadotropin (hCGbeta), or alpha-fetoprotein (AFP) levels can predict preeclampsia. METHODS:A population-based cohort included 1037 nulliparous women, of whom 637 (61%) p...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(98)00112-4
更新日期：1998-06-01 00:00:00
abstract：OBJECTIVE:To determine the association of intimate partner violence with maternal cigarette smoking before and during pregnancy. METHODS:Data were obtained for 196,391 U.S. mothers who delivered live neonates from 2004-2008 and completed the Pregnancy Risk Assessment Monitoring System survey 2-9 months postpartum. Int...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000000609
更新日期：2015-02-01 00:00:00
abstract：:A rapid, simple method for screening individuals at high risk for the presence of Y chromosomes is described. The correlation with actual sex using probability tables from Baye's formula have shown to be accurate, when used with a 99% confidence limit. This procedure can be utilized in the investigation of amenorrhea ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1976-12-01 00:00:00
