Abstract:
:This report presents a method for tracking Motor Evoked Potential (MEP) amplitudes over the course of a case using a moving least squares linear regression (LSMAs). During a case, newly obtained MEP amplitudes are compared to those predicted by a just previous linear regression (least squares moving average or LSMA). When detected by this comparison, a set criterion amplitude loss will then trigger linear regression of ensuing MEP amplitudes on an expanding step function which tracks the persistence of the amplitude loss for the remainder of the case. Three cases are presented. One in which the patient woke up with a newly acquired weakness in the left tibialis anterior and another in which MEP amplitudes were suddenly lost from the right foot, but after intervention, they were restored again. In a third case the patient again woke up with a new post-operative deficit, but MEP trial sampling had been more limited and variable than in the first two cases. When the linear trending method was applied to the affected myotome in the first case, the expanding step function regression was triggered after the moment of MEP loss and remained at a high level until the end of case. In the second case, the expanding step function regression was also triggered in the relevant myotome at the time of the reported MEP change, but diminished by end of case. In the third case the tracking method again successfully triggered a predictive R-Square despite the limited number of pre-event trials. The R-Square value of the expanding step function regression appears to have discriminative capability with regard to new post-op deficit. Given the importance of the intra-operative MEP for monitoring motor functioning and the high degree of variability that can affect it, the development of new quantitative, statistical methods to detect real from apparent MEP change will be necessary.
journal_name
J Clin Monit Computjournal_title
Journal of clinical monitoring and computingauthors
Jasiukaitis P,Lyon Rdoi
10.1007/s10877-018-0181-9subject
Has Abstractpub_date
2019-06-01 00:00:00pages
481-491issue
3eissn
1387-1307issn
1573-2614pii
10.1007/s10877-018-0181-9journal_volume
33pub_type
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
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doi:10.1007/s10877-020-00481-3
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章,随机对照试验
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
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更新日期:2017-06-01 00:00:00
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journal_title:Journal of clinical monitoring and computing
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pub_type: 临床试验,杂志文章
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
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journal_title:Journal of clinical monitoring and computing
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pub_type: 杂志文章
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
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