当前位置： SCI文献检索 > Photodiagnosis and Photodynamic Therapy期刊下所有文献 > Complete remission of two patients with recurrent and wide spread extramammary Paget disease obtained from 5-aminolevulinic acid-based photodynamic therapy and imiquimod combination treatment.

Complete remission of two patients with recurrent and wide spread extramammary Paget disease obtained from 5-aminolevulinic acid-based photodynamic therapy and imiquimod combination treatment.

Abstract：

BACKGROUND:Extramammary Paget disease (EMPD) is an uncommon malignant neoplasm affecting apocrine gland-bearing skin which usually occurs in the anogenital area of patients older than 50 years. However, as EMPD in old men develops in penoscrotal area and sometimes asymptomatic, in situ or dermal invasion is usually widely spread before a confirmed diagnosis was made. Skin graft is needed after surgery. Both photodynamic therapy (PDT) and topical use of imiquimod reported effective for EMPD. METHODS:Two patients with recurrent and wide spread at penoscrotal and groin area were diagnosed EMPD by biopsy and histopathological and immunohistochemical examination. We use 6 cycles of 20% 5-aminolevulinic acid (ALA) photodynamic therapy guided by 5-ALA induced porphyrin fluorescence. After PDT, patients were treated by topical use of imiquimod to prevent the recurrence. RESULTS:After 6 cycles of PDT and imiquimod treatments, the patients' examination showed total remission. At the end of the 6 and 12 months, biopsy and pathology examination remain no signal of recurrence. No clinical recurrence after 24 and 36 months' follow up. CONCLUSION:The combination treatment with 20% PDT and imiquimod acquired complete remission in treatment for recurrent and wide spread extramammary Paget disease in two patients.

journal_name

Photodiagnosis Photodyn Ther

journal_title

Photodiagnosis and photodynamic therapy

authors

Jing W,Juan X,Li X,Jiayuan C,Qin H,Qing L,Shengmei X

doi

10.1016/j.pdpdt.2014.03.006

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

434-40

issue

3

eissn

1572-1000

issn

1873-1597

pii

S1572-1000(14)00042-8

journal_volume

11

pub_type

杂志文章

相关文献

Photodiagnosis and Photodynamic Therapy文献大全
  • Hyperspectral imaging for diagnosis and detection of ex-vivo breast cancer.

    abstract：BACKGROUND AND PURPOSE:Breast cancer is one of the most widely recognized tumors. .Diagnosis made in the early stage of disease may imporve outcomes. The discovery of malignant growth utilizing noninvasive light intrusive methods in lieu of conventional excisional biopsy may assist in achieving this goal. MATERIALS AN...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101922

    authors： Aboughaleb IH,Aref MH,El-Sharkawy YH

    更新日期：2020-09-01 00:00:00

  • DAFE autofluorescence assessment of oral cavity, larynx and bronchus in head and neck cancer patients.

    abstract：:Head and neck (H&N) cancer patients have a high incidence of local field change as well as second primary lung tumours. We have applied the Wolf Diagnostic Autofluorescence Endoscopy (DAFE) system in a novel way, combining autofluorescence evaluation of both H&N region and bronchial. New H&N cases as well as "old" cas...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2006.07.004

    authors： Fielding D,Agnew J,Wright D,Hodge R

    更新日期：2006-12-01 00:00:00

  • Ultraviolet radiation exposure during daylight Photodynamic Therapy.

    abstract：BACKGROUND:Daylight photodynamic therapy (dPDT) is an effective treatment for field-change actinic keratoses (AK), with similar efficacy to conventional PDT but lower patient pain scores. Whilst AK occur consequent to chronic solar ultraviolet (UV) exposure, paradoxically solar visible radiation is used during PDT. OB...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2019.05.020

    authors： McLellan LJ,O'Mahoney P,Khazova M,Higlett M,Ibbotson SH,Eadie E

    更新日期：2019-09-01 00:00:00

  • Effect of 5-aminolevulinic acid photodynamic therapy on the expression of apoptosis inhibitors Bcl-2 and Survivin in keratinocytes of condyloma acuminatum.

    abstract：BACKGROUND:Condyloma acuminatum is a highly infectious disease caused by the human papillomavirus. Previous studies have shown that 5-aminolevulinic acid photodynamic therapy can inhibit proliferation of condyloma acuminatum keratinocytes. However, the effect of 5-aminolevulinic acid photodynamic therapy on condyloma a...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2019.07.018

    authors： Yin G,Li X,Wang X,Zhang H

    更新日期：2019-12-01 00:00:00

  • Real-world experience with 5-aminolevulinic acid for the photodynamic diagnosis of bladder cancer: Diagnostic accuracy and safety.

    abstract：BACKGROUND:5-Aminolevulinic acid (ALA)-mediated photodynamic diagnosis (PDD) has recently been approved in Japan for the management of non-muscle invasive bladder cancer. As such, the current study aimed to investigate the real-world diagnostic accuracy and safety of ALA-PDD-assisted transurethral resection of bladder ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101999

    authors： Yamamoto S,Fukuhara H,Karashima T,Inoue K

    更新日期：2020-12-01 00:00:00

  • Influence of ALA-mediated photodynamic therapy on secretion of interleukins 6, 8 and 10 by colon cancer cells in vitro.

    abstract：BACKGROUND:Photodynamic therapy has apart from a direct cytotoxic effect also immunomodulatory properties. The aim of our study was to investigate how photodynamic therapy with 5-aminolevulinic acid (ALA-PDT) in sublethal doses influences the secretion of interleukins 6, 8 and 10 from colon cancer cells in vitro. METH...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2018.02.021

    authors： Kawczyk-Krupka A,Czuba Z,Latos W,Wasilewska K,Verwanger T,Krammer B,Sieroń A

    更新日期：2018-06-01 00:00:00

  • Effect of phototherapy on dentin bond strength and microleakage when bonded to resin with different conditioning regimes.

    abstract：AIM:To assess the efficacy of phototherapy on bond strength and microleakage of bulk fill composites in comparison to conventional dentin surface treatments. MATERIALS AND METHODS:Ninety human third molars were divided into 3 groups (n = 30 each) according to surface conditioning treatment. Group 1 (Etch and Bond) EB,...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2018.12.014

    authors： Al Rifaiy MQ,Vohra F

    更新日期：2019-03-01 00:00:00

  • Photodynamic therapy in wound healing in vivo: a systematic review.

    abstract：:Wounds constitute severe problems in public health. Inappropriate manipulation to promote wound healing and indiscriminate use of antibiotics may contribute to failure in wound treatment, leading to bacterial growth and resistance. Appropriate and correct approaches to wound treatment are crucially important. Further,...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101682

    authors： Oyama J,Fernandes Herculano Ramos-Milaré ÁC,Lopes Lera-Nonose DSS,Nesi-Reis V,Galhardo Demarchi I,Alessi Aristides SM,Juarez Vieira Teixeira J,Gomes Verzignassi Silveira T,Campana Lonardoni MV

    更新日期：2020-06-01 00:00:00

  • Autofluorescence spectroscopy for NADH and flavoproteins redox state monitoring in the isolated rat heart subjected to ischemia-reperfusion.

    abstract：BACKGROUND:Reduction of myocardial ischemia-reperfusion injury in the patients undergoing cardiac surgery under cardiopulmonary bypass represents an important goal. Intraoperative monitoring of myocardial metabolic state using continuous registration of nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucl...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2014.05.003

    authors： Papayan G,Petrishchev N,Galagudza M

    更新日期：2014-09-01 00:00:00

  • Photodynamic therapy for Barretts' adenocarcinoma associated with an Angelchik device.

    abstract：:We present a novel case of an elderly patient with a Barrett's adenocarcinoma in the presence of an Angelchik prosthesis. We aim to draw attention to issues relating to metaplastic Barretts' oesphagus and its adenocarcinoma complications and highlight relevant issues in multimodal endoscopic management and palliation ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/S1572-1000(05)00091-8

    authors： Jenkins JT,Charles A,Mitchell KG,Fullarton GM

    更新日期：2005-09-01 00:00:00

  • Taking treatment decisions in non-melanoma skin cancer--the place for topical photodynamic therapy (PDT).

    abstract：BACKGROUND:Epithelial non-melanoma skin cancer (NMSC) like actinic keratosis (AK), Bowen's disease (BD) and basal cell carcinoma (BCC) represent the most common malignancies in the fair skinned population. Epidemiological data reveal high incidences, especially for actinic keratoses, which are basically non-invasive sq...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章,评审

    doi：10.1016/j.pdpdt.2009.12.004

    authors： Sidoroff A,Thaler P

    更新日期：2010-03-01 00:00:00

  • Antimicrobial activity of hypochlorite solutions and reciprocating instrumentation associated with photodynamic therapy on root canals infected with Enterococcus faecalis - An in vitro study.

    abstract：INTRODUCTION:The aim of this study is to evaluate the antimicrobial activity of hypochlorite solutions and reciprocating instrumentation associated with photodynamic therapy (PDT). METHODS:One hundred and thirty two root canals were enlarged up to #35 K-file and inoculated with E.faecalis for 14 days. The 132 samples ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2018.07.015

    authors： Souza MA,Tumelero Dias C,Zandoná J,Paim Hoffmann I,Sanches Menchik VH,Palhano HS,Bertol CD,Rossato-Grando LG,Cecchin D,de Figueiredo JAP

    更新日期：2018-09-01 00:00:00

  • Downregulation of Rac1/PAK1/LIMK1/cofilin signaling pathway in colon cancer SW620 cells treated with Chlorin e6 photodynamic therapy.

    abstract：BACKGROUND:Colorectal cancer is one of the most common gastrointestinal malignancies. Photodynamic therapy (PDT) is a novel and non-invasive treatment for multiple tumors with its features of small trauma, good applicability, accurate targeting, etc. PDT is also a potential treatment for colon cancer that induces lots ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.102143

    authors： Wufuer R,Ma HX,Luo MY,Xu KY,Kang L

    更新日期：2020-12-08 00:00:00

  • Mitomycin C-induced cell cycle arrest enhances 5-aminolevulinic acid-based photodynamic therapy for bladder cancer.

    abstract：BACKGROUND:Photodynamic therapy (PDT) and diagnosis (PDD) using 5-aminolevulinic acid (ALA) to control the production of the intracellular photosensitizer protoporphyrin IX (PpIX) are commonly used clinically. Previously, we demonstrated that dormant and drug-induced dormancy-like cancer cells accumulated high PpIX lev...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101893

    authors： Nakayama T,Nozawa N,Kawada C,Yamamoto S,Ishii T,Ishizuka M,Namikawa T,Ogura SI,Hanazaki K,Inoue K,Karashima T

    更新日期：2020-09-01 00:00:00

  • In vivo temporal evolution of ALA-induced normalized fluorescence at different anatomical locations of oral cavity: application to improve cancer diagnostic contrast and potential.

    abstract：BACKGROUND:The focal goal of this study is to identify optimal accumulation periods for ALA-induced PpIX in different healthy anatomical sites of human oral cavity and different types of abnormal mucosa to improve the accuracy of the clinical applications such as photodiagnosis and tissue grading. MATERIALS AND METHOD...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2010.06.006

    authors： Mallia RJ,Subhash N,Sebastian P,Kumar R,Thomas SS,Mathews A,Madhavan J

    更新日期：2010-09-01 00:00:00

  • Photodynamic effect of curcumin on Vibrio parahaemolyticus.

    abstract：:Vibrio parahaemolyticus (V. parahaemolyticus) is currently a major cause of bacterial diarrhoea associated with seafood consumption. The objective of this study was to determine the inactivation effect of curcumin-mediated photodynamic action on V. parahaemolyticus. First of all, V. parahaemolyticus suspended in PBS b...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2016.05.004

    authors： Wu J,Mou H,Xue C,Leung AW,Xu C,Tang QJ

    更新日期：2016-09-01 00:00:00

  • In vitro evaluation of methylene blue removal from root canal after Photodynamic Therapy.

    abstract：:In Endodontics, photosensitizers' such as methylene blue and toluidine blue have been used in Photodynamic Therapy due to their positive results. However, they can stain the dentin from the root canal after Photodynamic Therapy (PDT). The present in vitro study aimed to evaluate different stain removal protocols from ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2017.10.024

    authors： Ramalho KM,Cunha SR,Mayer-Santos E,Eduardo CP,Freitas PM,Aranha ACC,Moura-Netto C

    更新日期：2017-12-01 00:00:00

  • Comparison of 5-aminolevulinic acid photodynamic therapy and red light for treatment of photoaging.

    abstract：OBJECTIVE:The aim of this pilot study was to compare the efficacy of ALA-PDT and red light alone in the treatment of photoaging. METHODS:A total of 14 adults with photoaging skin were recruited. ALA-PDT or red light alone was applied to the forearm extensor. Before and after treatment, the treated sites were examined ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2014.02.007

    authors： Ji J,Zhang LL,Ding HL,Wang HW,Huang Z,Wang XX,Wang PR,Wang XL

    更新日期：2014-06-01 00:00:00

  • Deep proteome profiling of SW837 cells treated by photodynamic therapy (PDT) reveals the underlying mechanisms of metronomic and acute PDTs.

    abstract：AIM:Metronomic photodynamic therapy (mPDT) with a longer irradiation time and lower energy compared with acute (or classic) photodynamic therapy (aPDT) is a more effective treatment than aPDT for tumor cells, especially colorectal cancer. However, the underlying mechanisms of the superior effects of mPDT are unknown. ...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101809

    authors： Gao H,Shi X,Chen Q,Che B,Yin H,Li Y

    更新日期：2020-09-01 00:00:00

  • Effects of low-dose ALA-PDT on fibroblast photoaging induced by UVA irradiation and the underlying mechanisms.

    abstract：OBJECTIVES:To investigate the effects of low-dose aminolevulinic acid photodynamic therapy (ALA-PDT) on photoaging in human dermal fibroblasts (HDFs) and to explore the mechanism of Nuclear factor erythroid 2-related factor 2(Nrf2)-mediated photorejuvenation in vitro. METHODS:A photoaging model was established through...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2019.05.006

    authors： Chen J,Luo J,Tan Y,Wang M,Liu Z,Yang T,Lei X

    更新日期：2019-09-01 00:00:00

  • Antibacterial effect of S-Porphin sodium photodynamic therapy on Staphylococcus aureus and multiple drug resistance Staphylococcus aureus.

    abstract：BACKGROUND:Antibacterial photodynamic therapy (aPDT) has been proposed as an alternative strategy to inactivate bacteria. This study was designed to investigate the antibacterial effect of a novel photosensitizer S-Porphin sodium (S-PS) on plankton and biofilm cultures of Staphylococcus aureus (S. aureus) and its multi...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2019.08.031

    authors： Jia M,Mai B,Liu S,Li Z,Liu Q,Wang P

    更新日期：2019-12-01 00:00:00

  • The application of 5-aminolevulinic acid-induced fluorescence for cystoscopic diagnosis and treatment of bladder carcinoma.

    abstract：PURPOSE:To investigate the clinical application of 5-aminolevulinic acid (ALA) assisted fluorescence cystoscopy for early detection of bladder carcinoma and completely transurethral resection. METHOD:ALA-assisted fluorescence cystoscopy was performed on 51 cases of anodynia haematuria. Fluorescence cystoscopy was perf...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2006.12.001

    authors： Song X,Ye Z,Zhou S,Yang W,Zhang X,Liu J,Ma Y

    更新日期：2007-03-01 00:00:00

  • 5-aminolevulinic acid mediated photodynamic therapy inhibits survival activity and promotes apoptosis of A375 and A431 cells.

    abstract：OBJECTIVES:The purpose of this study was to investigate the effects of 5-aminolaevulinic acid mediated photodynamic therapy (ALA-PDT) on the survival activity and apoptosis of human melanoma cell line A375 and non-melanoma skin carcinoma cell line A431 cells. The mechanism for cellular apoptosis was explored. METHODS:...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2018.01.004

    authors： Cai J,Zheng Q,Huang H,Li B

    更新日期：2018-03-01 00:00:00

  • Photodynamic therapy with the use of superluminescent diodes (sLED) in the treatment of actinic keratosis.

    abstract：BACKGROUND:Superluminescent diodes (sLED) appear to be an innovative and promising light source in photodynamic therapy (PDT), especially in actinic keratosis (AK) lesions treatment. AIM:Assessment of tolerability and efficacy of sLED in topical 5-aminolevulinic acid (ALA) PDT of AK lesions. METHODS:27 patients recei...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2018.04.010

    authors： Bartosińska J,Wolska-Gawron K,Gerkowicz A,Niewiedzioł M,Michalska-Jakubus M,Komza M,Klepaczewski T,Kwaśny M,Krasowska D

    更新日期：2018-06-01 00:00:00

  • Acanthopanacis Cortex extract: A novel photosensitizer for head and neck squamous cell carcinoma therapy.

    abstract：OBJECTIVES:The aim of this study was to develop a novel photosensitizer from traditional plant extracts and to investigate the photodynamic therapy (PDT) effect and mechanism of action of the novel photosensitizer on KB and Hep-2 cells. METHODS:Fluorescence emission, cell viability, and intracellular distribution of c...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2019.02.020

    authors： Shi S,Cho H,Sun Q,He Y,Ma G,Kim Y,Kim B,Kim O

    更新日期：2019-06-01 00:00:00

  • Vascular targeted photodynamic therapy for bleeding gastrointestinal mucosal vascular lesions: a preliminary study.

    abstract：BACKGROUND:Vascular-targeted photodynamic therapy (V-PDT) has shown good selectivity and efficacy in the treatment of certain types of vascular disease, including port wine stains, age-related macular degeneration, and esophageal varices. This study was conducted to test the efficacy and safety of V-PDT in the treatmen...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2011.11.003

    authors： Qiu H,Mao Y,Gu Y,Wang Y,Zhu J,Zeng J

    更新日期：2012-06-01 00:00:00

  • Synthesis, spectral characterization, crystal structure, cytotoxicity and apoptosis-Inducing activity of two derivatives of 2-hydroxy-1,4-naphthaquinone.

    abstract：:A phenaxazone compound [5H-Benzo[a]phenoxazin-5-one (BP)] along with an aminoquinone[2-[(o-hydroxyphenyl)amino]-1,4-naphthaquinone (HAN)] derivatives were synthesized from lawsone using ultrasound irradiation technique. The structure of the compounds were characterized by elemental analysis and various spectral studie...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2017.01.180

    authors： P R KR,Fernandez A,Laila SP,B A,C S S,V S V

    更新日期：2017-03-01 00:00:00

  • Delineation of the Arm Blood Vessels Utilizing Hyperspectral Imaging to Assist with Phlebotomy for Exploiting the Cutaneous Tissue Oxygen Concentration.

    abstract：SIGNIFICANCE:The estimation of tissue oxygenation is vital in the diagnosis and therapeutic evaluation of a huge assortment of diseases. However, the hyperspectral (HS) imaging system is a rising innovation that can be utilized to build a highly sensitive, non-invasive, and tissue hemoglobin immersion map. OBJECTIVE:A...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2021.102190

    authors： Fouad Aref MH,Sharawi AAR,El-Sharkawy YH

    更新日期：2021-01-25 00:00:00

  • The assessment of different bleaching agents' efficiency on discoloured teeth using image-processing methods.

    abstract：BACKGROUND:Although triple antibiotic paste (TAP) has been successfully used as an intracanal medicament for regenerative endodontic treatments, TAP has also been shown to cause discolouration. The aim of this study is to investigate the efficacy of different bleaching agents to bleach teeth discoloured from TAP. METH...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101901

    authors： Ozkocak I,Hekim M,Gokturk H,Adem K,Comert O

    更新日期：2020-09-01 00:00:00

  • In vivo detection of circulating tumour cell clusters by photodiagnostic spectroscopy.

    abstract：BACKGROUND:We demonstrate a new diagnostic method, Photodiagnostic Infrared Spectroscoppy (PDIS), which is able to detect circulating tumor clusters and circulating tumor cells in the circulatory system. METHODS:The PDIS method is based on photodiagnostic physics and high resolution spectroscopy and is using calibrate...

    journal_title：Photodiagnosis and photodynamic therapy

    pub_type： 杂志文章

    doi：10.1016/j.pdpdt.2020.101755

    authors： Schikora D

    更新日期：2020-06-01 00:00:00