Abstract:
BACKGROUND:The gastroesophageal reflux disease (GERD) questionnaire (GerdQ) is a validated questionnaire that was developed recently to help identify GERD patients. The sensitivity and specificity of GerdQ for the diagnosis of GERD in adult patients were 65% and 71%, respectively. Because the application of GerdQ in pediatric population is largely unknown, the aim of this study is to establish the endoscopic correlation between Chinese GerdQ and grades of erosive esophagitis (EE) in Taiwanese children. METHODS:Seventy-four children (aged 9-18 years) were evaluated by our version of the Chinese GerdQ prior to receiving esophagogastroduodenoscopy for warning upper gastrointestinal symptoms. Grades of EE were assessed blindly, according to the Los Angeles classification. The sensitivity and specificity of GerdQ for detecting endoscopic EE were analyzed. RESULTS:In 74 patients, the male to female ratio was 1:1.1 and the mean age was 14.2 ± 2.3 years (age range: 9.2-17.9 years). Thirty-nine percent of the enrolled patients had EE. The sensitivity and specificity of GerdQ (with a cutoff score of ≥7) to identify EE patients were 65.5% and 80%, respectively. The odds ratio of GerdQ for a cutoff score of 7 to identify EE was 7.6 (95% confidence interval = 2.6-21.9, p < 0.001). CONCLUSION:For the identification of EE in children, the Chinese GerdQ had similar sensitivity and specificity to that used for adults. This questionnaire may be applied as a noninvasive screening tool.
journal_name
Pediatr Neonatoljournal_title
Pediatrics and neonatologyauthors
Chiu JY,Wu JF,Ni YHdoi
10.1016/j.pedneo.2014.01.004subject
Has Abstractpub_date
2014-12-01 00:00:00pages
439-43issue
6eissn
1875-9572issn
2212-1692pii
S1875-9572(14)00036-9journal_volume
55pub_type
杂志文章abstract:BACKGROUND:The parameters of oxidative stress [advanced oxidation protein products (AOPPs), malondialdehyde (MDA), and S100B] and the effect of intensive phototherapy (PT) on these parameters have not been studied extensively in newborns with significant hyperbilirubinemia (SH). We aimed to measure the levels of MDA, S...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2014.06.006
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Neonatal sepsis contributes to great mortality and morbidity among very-low-birth-weight (VLBW) infants. Prevalence and pathogen distribution of sepsis in the neonatal intensive care units (NICUs) vary with time and geographic location. Such information serves as a guide for selection of empirical antibiotic...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2012.06.003
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:We aimed to study the changes of serum N-terminal pro-brain natriuretic to peptide (NT-proBNP) levels after asphyxia-induced myocardial injury in children and explore the relationship between serum NT-proBNP levels and neonatal asphyxia. METHODS:One hundred and six cases of neonatal asphyxia were randomly s...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2015.08.001
更新日期:2016-04-01 00:00:00
abstract::Juvenile myelomonocytic leukemia (JMML) is a rare hematologic malignancy in children. Its presentations include anemia, thrombocytopenia, monocytosis, skin rash, marked hepatomegaly, and/or splenomegaly. Fever and respiratory involvement are common. Here, we report a case of a premature neonate with initial symptoms o...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2013.06.009
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Zellweger syndrome (ZS) is a peroxisome biogenesis disorder attributed to a mutation of the PEX genes family. The incidence of this disease in Africa and the Arab world remains unknown. This contribution is aimed at describing the clinical phenotype and biochemical features in Tunisian patients with ZS in or...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2016.08.011
更新日期:2017-12-01 00:00:00
abstract::Pneumothorax-associated pneumoretroperitoneum and perirenal air have rarely been reported in infants. We report a case of an extremely low-birth-weight infant who developed pneumoretroperitoneum and perirenal air associated with tension pneumothorax and deteriorated acutely despite prompt pleural water-seal vacuum dra...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2010.12.004
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Management of a first attack of acute urticaria in children is dependent on the etiology of the disease. Knowledge of the various etiologies of urticaria will help primary physicians to perform appropriate clinical assessments. In this study, we analyzed the etiologies and their prevalence in first-attack ac...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/S1875-9572(08)60014-5
更新日期:2008-06-01 00:00:00
abstract::Glycogen storage disease (GSD) type Ib is caused by the deficiency of glucose-6-phosphate translocase activity. The elder brother of the proband died at age 20 months, and GSD Ia, a disease caused by the deficiency of glucose-6-phosphatase, was the diagnosis. Theproband developed hypoglycemia shortly after birth. Diet...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/S1875-9572(09)60048-6
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Lenticulostriate vasculopathy is associated with various disorders, in particular cytomegalovirus infection, which can cause neurological consequences. We wanted to evaluate the association of lenticulostriate vasculopathy and cytomegalovirus infection. We retrospectively collected data on lenticulostriate v...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2015.04.002
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Kawasaki disease (KD), first described by Dr. Tomisaku Kawasaki in 1967, was found for the first time in Taiwan in 1976. It continued to occur in increased numbers. For the study of incidence rates and epidemiological features of KD, we conducted five nationwide hospital surveys (NHS) in 1987, 1992, 1994, 20...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2013.05.011
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Nonketotic hyperglycinemia (NKH) is a rare, inherited disease, with very poor outcome. It is difficult to confirm the diagnosis due to nonspecific presentations and rapid progression. The incidence was reported in a few countries. We report the clinical and genetic features of typical neonatal NKH with novel...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2015.10.008
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Parents often express concerns about feeding difficulties in their child. We hypothesized that these parental concerns were associated with adverse growth status in early childhood. We aimed to determine the prevalence of such concerns and whether these concerns were associated with adverse growth status in ...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2019.04.004
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Anterior displacement of the anus has been reported to be a cause of chronic constipation amongst young children. However, the normal position of the anus has not been studied in Taiwan. PATIENTS AND METHODS:Normal anal positioning was studied in 200 neonates (100 males and 100 females). All of these indivi...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/S1875-9572(09)60055-3
更新日期:2009-08-01 00:00:00
abstract::Interstitial deletion of the proximal short arm of chromosome 4 has rarely been described. This defect is associated with variable clinical manifestations, including mental retardation, unusual facial appearance, and minor limb abnormalities. We describe a girl diagnosed with moderate mental retardation and seizures w...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2011.03.009
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:To improve the objective assessment of continuous video-EEG (cEEG) monitoring of neonatal brain function, the aim was to relate automated derived amplitude and duration parameters of the suppressed periods in the EEG background (dynamic Interburst Interval= dIBIs) after neonatal hypoxic-ischemic encephalopat...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2018.03.010
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Meconium peritonitis (MP) develops when bowel perforation occurs in utero or soon after birth, resulting in leakage of meconium into the peritoneal cavity. The clinical features are often variable and prenatal ultrasonography plays an important role in prenatal diagnosis. METHODS:We conducted a retrospectiv...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/s1875-9572(09)60034-6
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Tracheostomy is a valuable procedure in infants and neonates with chronic respiratory failure or severe airway obstruction. The aim of this study is to identify the indication, hospital course, and long-term outcome in a cohort of infants who required tracheostomy in a neonatal and pediatric tertiary care ce...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2017.07.003
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:This study was conducted to investigate whether glycated albumin is a useful glycemic marker from the point of view of infant complications for monitoring glycemic control in pregnant women with diabetes or gestational diabetes mellitus. METHODS:We retrospectively studied 42 Japanese infants of diabetic mot...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2016.02.003
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:The benefits of feeding human milk to infants, even in prematurity, have been well documented. Well-organized donor milk processing has made the milk bank a good source of nutrition for premature or sick infants if their own mother's milk is not sufficient or suitable. The Taipei City Hospital Milk Bank was ...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2012.11.004
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Human metapneumovirus (HMPV) is a recently discovered respiratory pathogen of the family Paramyxoviridae, the same family as that of respiratory syncytial virus (RSV). Premature children are at high risk of severe RSV infections, however, it is unclear whether HMPV infection is more severe in hospitalized ch...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2015.03.008
更新日期:2016-02-01 00:00:00
abstract::Recently, heated humidified high-flow nasal cannula (HHHFNC) has been introduced and applied as a noninvasive respiratory support in neonates. Although HHHFNC is widely used in neonates presenting with respiratory distress, the efficiency and safety when compared with nasal continuous positive airway pressure or nonin...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章,评审
doi:10.1016/j.pedneo.2016.08.007
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:The most severe form of pneumococcal disease is invasive pneumococcal disease (IPD), including empyema, sepsis and meningitis. Thomsen-Friedenreich antigen (TA; Galβ1-3GalNAc) activation is known to be a predictor of Streptococcus pneumoniae-associated hemolytic uremic syndrome (Sp-HUS). There have been limi...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2020.02.005
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Community-acquired Gram-Negative (GN) bacteremia caused more morbidity and mortality recently in children. The increasing drug resistance was also an important issue. However, published reference was few about children. METHODS:We conducted a retrospective study to collect febrile patients with blood cultur...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2019.05.009
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Persistent pulmonary hypertension of the newborn (PPHN) contributes to neonatal hypoxemia and is associated with a high mortality. Some PPHN patients are unresponsive to inhaled nitric oxide (iNO). Bosentan, an oral endothelin-1 receptor antagonist, reduces pulmonary vascular resistance and hence may play a ...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2017.02.003
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:The noisy component of bubble continuous positive airway pressure (CPAP) is thought to contribute to breathing efficiency and lung volume recruitment, mainly because of stochastic resonance. The magnitude and frequency of the superimposed noise are vital to this process. We wanted to evaluate the in vitro ef...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2012.08.013
更新日期:2012-12-01 00:00:00
abstract::Head trauma is one of the most challenging fields of traumatology and demands immediate attention and intervention by first-line clinicians. Symptoms can vary from victim to victim and according to the victim's age, leading to difficulties in making timely and accurate decisions at the point of care. In children, fall...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章,评审
doi:10.1016/j.pedneo.2012.12.011
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Thrombotic microangiopathies (TMA) are microvascular occlusive disorders characterized by systemic or intrarenal platelet aggregation, thrombocytopenia, and red cell fragmentation. Post-operative TMA mostly occurs in adult patients with cardiovascular surgery, with the distinct pathophysiology from classical...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2018.02.002
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:The study of genetic polymorphisms of surfactant-lipids related genes can help to understand individual variability in the susceptibility to development of pulmonary pathologies. The purpose of this study was to evaluate the association of polymorphisms of surfactant-lipids related genes (LPCAT1, CHPT1 and P...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2019.12.012
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:There are few reports on the symptoms of rotavirus infections in neonates. This study aims to describe clinical signs of rotavirus infections among neonates, with a particular focus on preterm infants, and to show the distribution of genotypes in a neonatal intensive care unit (NICU). METHODS:A prospective ...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2011.11.005
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:We determined the chest height in a cohort of patients with primary spontaneous pneumothorax (PSP) who had received chest radiographic examinations prior to the attack. The aim of this study was to determine when their chest height began to change and how this was related to the PSP. METHODS:From June 2009 ...
journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2014.07.002
更新日期:2015-02-01 00:00:00