Abstract:
:Stem and progenitor cell research is a complex and exciting field which promises curative discoveries in numerous areas including cancer, diabetes, and regenerative medicine. Use of biotic factors or growth factors has played an essential role in the development of stem cell research. These biologically active components have been administered into stem cells either to improve or maintain the stem cell proliferation, or to encourage controlled differentiation into more defined cell types. Small molecules such as 6-Bromoindirubin-3´-oxime (BIO), cardiogenol-C, etc can help stem cell research by controlling or influencing the regulatory changes in a controlled manner and to help understand the mechanisms during stem cell differentiation. Extra cellular matrix (ECM) is another significant biotic factor, which mediates cell and tissue behavior by influencing cell-matrix interactions. Thus, in this review we would like to emphasize significance of various growth factors in stem cell research.
journal_name
Curr Stem Cell Res Therjournal_title
Current stem cell research & therapyauthors
Baadhe RR,Mekala NK,Potumarthi Rdoi
10.2174/1574888x09666140507124727subject
Has Abstractpub_date
2014-01-01 00:00:00pages
489-96issue
6eissn
1574-888Xissn
2212-3946pii
CSCRT-EPUB-60404journal_volume
9pub_type
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journal_title:Current stem cell research & therapy
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journal_title:Current stem cell research & therapy
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pub_type: 杂志文章,meta分析
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:Current stem cell research & therapy
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journal_title:Current stem cell research & therapy
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更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章,评审
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abstract::Mesenchymal stem cells (MSCs) have been isolated not only from bone marrow, but also from many other tissues such as adipose tissue, skeletal muscle, liver, brain and pancreas. Because MSC were found to have the ability to differentiate into cells of multiple organs and systems such as bone, fat, cartilage, muscle, ne...
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