Abstract:
:DNA analysis was performed by flow cytometry (FCM) in 59 cases of different types of pituitary adenomas who underwent microsurgery and were actively followed over a period of 3-6 years. Aneuploid DNA patterns were detected in 12 (20%) cases. Frequency of aneuploidy was highest in prolactin-secreting (36%) as compared to 17% in GH- and 7% in non-secreting adenomas. Some adenoma parameters valid for tumour growth, such as rate of recurrences and mitotic index, were correlated with aneuploidy of the tumour. FCM studies are, therefore, recommended to gain further parameters for the estimation of proliferative activity of pituitary adenomas.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Lüdecke DK,Beck-Bornholdt HP,Saeger W,Schmidt Wdoi
10.1007/BF01403824subject
Has Abstractpub_date
1985-01-01 00:00:00pages
18-22issue
1-2eissn
0001-6268issn
0942-0940journal_volume
76pub_type
杂志文章abstract:OBJECTIVES:Ballistic injuries to peripheral nerves pose special challenges in terms of indications, timing and type of surgical intervention. The aim of the present work was to analyze our experience in the surgical treatment of peripheral nerve ballistic injuries with respect to the mechanism of injury (gunshot versus...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-014-2139-0
更新日期:2014-08-01 00:00:00
abstract::We report the case of a large osteoblastoma arising in the frontal bone of a 20-year-old female. The lesion was first noted after a fall, and grew steadily in size following further head injury during pregnancy. Initial plain radiography demonstrated an area of radiolucency, with subsequent cross-sectional imaging rev...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-016-3024-9
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Spinal intramedullary arteriovenous malformations (AVMs) fed by an anterior spinal artery are surgically challenging vascular lesions. METHOD:We herein presented microsurgical resection techniques for an intramedullary glomus AVM located in the lateral part of the high cervical spinal cord with an operative...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-015-2531-4
更新日期:2015-10-01 00:00:00
abstract:STUDY DESIGN:Spinal subarachnoid hematomas are unusual and difficult to diagnose and the outcome of treatment is influenced by the lesions that frequently accompany them. OBJECTIVES:To clarify the neuroradiological diagnostic aspects of spinal subarachnoid hematoma as well as the results of treatment. BACKGROUND:Only...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-004-0458-2
更新日期:2005-07-01 00:00:00
abstract::Subdural collections or hematomas are frequently observed after shunt placement [7-9, 13], but rarely after ETV [6]. A review of literature revealed 7 cases [1, 5, 6, 10, 12], of which only 1 was symptomatic [5]. We will discuss the causes, management, and methods of prevention of this complication and we will present...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-005-0715-z
更新日期:2006-05-01 00:00:00
abstract::The clinico-pathological findings are reported in a case with persistent vegetative state after multiple cerebral lesions. The lesions are small in size, and are situated at different levels of the CNS, some of them being important in the maintenance of wakefulness and motor initiative. The differential diagnosis and ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01411190
更新日期:1981-01-01 00:00:00
abstract::Giant cell tumors of the spine are uncommon. Usually they are benign and solitary, but locally very aggressive. Most of them occur at the sacral spine. There are only 26 reported cases in the literature involving this type of tumor in the lumbar spine, in particular exhibiting an intraperitoneal growth. We present the...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-013-1713-1
更新日期:2013-07-01 00:00:00
abstract::Four patients harbouring a colloid cyst of the 3rd ventricle were operated on endoscopically. With the "classical" monoportal technique, through a precoronal burr hole only partial removal could be achieved in the first case. As the crucial point of the procedure is the safe dissection of the cyst from the thela chori...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050466
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:The management of pineal cysts is still debatable, especially for asymptomatic incidental ones. For symptomatic cysts associated with hydrocephalus, the surgical management is mandatory and may include either classical microsurgical approaches to the pineal region or endoscopic trans-ventricular approaches i...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1849-z
更新日期:2013-10-01 00:00:00
abstract::Two-hundred seven patients who were operated on consecutively between January 1983 and December 1990 to relieve disabling positional vertigo (DPV) using the microvascular decompression (MVD) procedure were studied. Selection of the patients for MVD operations was based on both case history and the results of otoneurol...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401831
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:To illustrate the use of indocyanine green (ICG) video-angiography to confirm abolition of spinal dural arteriovenous fistula (SDAVF) and preserve the normal vascular anatomy intraoperatively. METHODS:A 73-year-old woman presenting with progressive myelopathy was diagnosed with an SDAVF, where the origin of th...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-009-0445-8
更新日期:2010-03-01 00:00:00
abstract::Hormonal disturbances caused by hypothalamic pathology can be treated effectively by target hormone replacement in the case of failure of glandotropic hormone secretion. Hyposomatotropism in children has to be substituted by parenteral administration of growth hormone. In addition gonadotropins respectively gonadotrop...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01406335
更新日期:1985-01-01 00:00:00
abstract::The application of gallium-67 (67Ga) citrate has not been reported for the detection of an intracranial germinoma. The purpose of this report is to further evaluate the effectiveness of 67Ga scintigraphy in neurohypophyseal germinomas. 67Ga studies in five male patients with histologically verified intracranial pure g...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010070109
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:In terms of response to fractionated radiotherapy, metastatic brain tumors of certain origins are considered radioresistant. OBJECTIVE:To determine the influence of "radioresistant" histology on outcomes of brain metastases treated with radiosurgery. METHODS:Between 2001 and 2017, 121 patients with brain m...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-018-3726-2
更新日期:2018-12-01 00:00:00
abstract:OBJECT:Hydrocephalus is characterised by elevated intracranial pressure (ICP) and gives rise to brain damage. The aim of this study was to investigate the significance of brain specific proteins as markers in the evaluation of brain damage in hydrocephalus. Therefore we determined the levels of four brain specific prot...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-002-1019-1
更新日期:2003-01-01 00:00:00
abstract::Eosinophilic granuloma (EG) is a rare disease but is more common in adults than children. It's often self-limiting. Spinal involvement is rare. It is the localized and most benign form of Langerhans' cell histiocytosis (previously known as histiocytosis X), characterised by lytic lesions in one or more bones. Spontane...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-003-0182-3
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Several models for the application of intra-operative magnetic resonance imaging (IMRI) have recently been reported, most of them unique. Two fundamental issues need to be addressed: optimal use of the scanner to ensure a wide base for research, development and clinical application, and an organisational mod...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010200035
更新日期:2002-03-01 00:00:00
abstract:BACKGROUND:We describe the management of osteomyelitis of the cervical spine, utilizing internal fixation with subsequent removal and culture of the implants. Four out of five patients had evidence of bacterial colonisation in close proximity to the internal fixation device. METHODS:Five consecutive patients (all fema...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-003-0129-8
更新日期:2003-11-01 00:00:00
abstract::The feline infusion model of brain edema was used to evaluate the pathophysiological effects of 0.6 ml infusions of autologous serum protein (66%), human serum protein (66%), human glioma cyst fluid and a tissue culture medium (TCM) on the structure and function of the forebrain white matter. These infusions increased...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02112037
更新日期:1993-01-01 00:00:00
abstract::We analyze a series of 44 medulloblastomas in patients aged 20 and older, listed in the Connecticut Tumor Registry. Average age was 34.1 years. Incidence was 0.058 per 100,000 per year. Headache and ataxia were the most frequent presenting complaints. Findings at diagnosis most often were papilloedema, cranial nerve p...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01419496
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an established therapeutic approach for the management of patients with late-stage idiopathic Parkinson's disease (PD). The aim of the present study was to assess regional cerebral blood flow (rCBF) changes related to mot...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-012-1610-z
更新日期:2013-03-01 00:00:00
abstract::A 35-year-old female presented with partial complex seizures. Computed tomography (CT) showed a slightly high density mass over the right frontal convexity, with heterogeneous contrast enhancement. T1-weighted magnetic resonance (MR) imaging showed the tumour as a hypo-intense lesion, with faint reticular enhancement ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050493
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Cerebrospinal fluid (CSF) shunting is a highly effective treatment for idiopathic normal pressure hydrocephalus (iNPH). However, secondary deterioration can occur at a later time. Thus, the current study aimed to evaluate the incidence rate and causes of secondary deterioration. METHODS:A retrospective anal...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-020-04475-7
更新日期:2020-10-01 00:00:00
abstract::Quantitative isotope ventriculography (QIV) has been suggested as a method for diagnosing hydrocephalus and predicting the results of CSF shunt insertion. However, the physiological significance of this and other tracer clearance studies is questionable. Using a simplified mathematical model for tracer clearance follo...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01808440
更新日期:1981-01-01 00:00:00
abstract::While bone invasion and hyperostosis are frequent phenomena in meningiomas, primary intra-osseous meningiomas are rare. With only 15 reported cases, the osteolytic form of primary intra-osseous meningiomas is most uncommon. Its occurrence in the skull base is an extra-ordinary exception. We have reviewed and categoriz...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-004-0380-7
更新日期:2004-11-01 00:00:00
abstract::The findings of computerized tomography and clinical features were studied in 19 patients with traumatic intraventricular haemorrhage. Blood was found in various portion of the ventricles. Main sites of the blood was as follows: around the foramen of Monro, 6 patients; in the body and occipital horn of the lateral ven...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01404144
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Some intracranial aneurysms treated by stent-assisted coiling (SAC) with incomplete occlusion undergo progressive occlusion (PO) during follow-up period. We analyzed the predictors for the occurrence of PO. METHODS:Among 74 cerebral aneurysms treated by SAC using the Enterprise or Neuroform stents from 2010...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-017-3199-8
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:By now it has been well established that vertebral artery injury (VAI) is associated with unstable cervical spine injuries resulting from blunt trauma. A more complete understanding of predisposing factors and the mechanism of injury in VAI should result in improved outcomes and reduced risk for patients wit...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-012-1499-6
更新日期:2012-11-01 00:00:00
abstract::We report 2 cases with haemorrhagic complications following percutaneous transluminal angioplasty (PTA) for carotid stenosis. Computed tomography (CT) scanning of these cases demonstrated diffuse subarachnoid haemorrhage in 1 case, and intracerebral haemorrhage in the other case on the next day after PTA. In the latte...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010070006
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:The understanding of molecular alterations of tumors has severely changed the concept of classification in all fields of pathology. The availability of high-throughput technologies such as next-generation sequencing allows for a much more precise definition of tumor entities. Also in the field of brain tumor...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-016-3062-3
更新日期:2017-03-01 00:00:00