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Internal fixation for osteomyelitis of cervical spine: the issue of persistence of culture positive infection around the implants.

Abstract：

BACKGROUND:We describe the management of osteomyelitis of the cervical spine, utilizing internal fixation with subsequent removal and culture of the implants. Four out of five patients had evidence of bacterial colonisation in close proximity to the internal fixation device. METHODS:Five consecutive patients (all female, ranging in age from 50 to 74 yrs) presenting with unstable cervical osteomyelitis were treated by surgical decompression, primary internal fixation followed by three months of intravenous antibiotics. The internal fixation was removed in 4 out of 5 cases within a year of stopping the intravenous regime. The remaining patient was deemed medically unfit for further operation. Multiple specimens from the screw sites were taken at the time of metal removal. A final course of oral antibiotics was prescribed based on the results of these specimens. FINDINGS:Four patients, who had removal of the implants, had positive cultures growing different bacteria from the primary infection, at the time of removal of the implant. None of the patients developed instability after removal of the implant. INTERPRETATION:Asymptomatic bacterial colonisation of a metallic implant has profound management implications. We recommend long-term oral antibiotic regimes after insertion of internal fixation devices in the face of infection and eventual removal of these implants and microbiological re-sampling.

journal_name

Acta Neurochir (Wien)

journal_title

Acta neurochirurgica

authors

Shad A,Shariff S,Fairbank J,Byren I,Teddy PJ,Cadoux-Hudson TA

doi

10.1007/s00701-003-0129-8

subject

Has Abstract

pub_date

2003-11-01 00:00:00

pages

957-60; discussion 960

issue

11

eissn

0001-6268

issn

0942-0940

journal_volume

145

pub_type

杂志文章

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