Serial transcranial Doppler measurements in traumatic brain injury with special focus on the early posttraumatic period.

Abstract:

BACKGROUND:Cerebral ischemia is considered a key factor in the development of secondary damage after Traumatic Brain Injury (TBI). Studies on Cerebral Blood Flow (CBF) have documented decreased flow in over 50% of patients with TBI, studied in the acute phase. Transcranial Doppler (TCD) sonography is a non-invasive technique, permitting frequent or continuous measurements of blood flow velocity in the basal cerebral arteries. OBJECTIVES:To investigate the potential of TCD to detect decreased blood flow velocity in the early phase after TBI;To investigate whether flow velocity differs between hemispheres in patients with focal lesions versus those with more diffuse injuries;To investigate if decreased blood flow velocity is indicative of cerebral ischemia, as evidenced by measurements of brain tissue pO(2). METHODS:TCD examinations were performed in 57 patients with severe TBI (GCS

journal_name

Acta Neurochir (Wien)

journal_title

Acta neurochirurgica

authors

van Santbrink H,Schouten JW,Steyerberg EW,Avezaat CJ,Maas AI

doi

10.1007/s00701-002-1012-8

subject

Has Abstract

pub_date

2002-11-01 00:00:00

pages

1141-9

issue

11

eissn

0001-6268

issn

0942-0940

journal_volume

144

pub_type

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