Abstract:
:The nucleotide sequence of tyrosine tRNAQ* psi A from bovine liver was determined to be pC-C-U-U-C-m2G-A-U-A-m2G-C-U-C-A-G-D-D-G-G-acp3U-A-G-A -G-C-m22G-m22G -A-G-G-A-C-U-Q*-psi-A-m1G-A-psi m-C-C-U-U-A-G-m7G-D-m5C-G-C-U-G-G-T-psi-C-G-m1A -U-U-C-C-G-G-C-U-C-G-A-A-G-G-A-C-C-AOH. This tyrosine tRNA is 76 nucleotides in length, and contains two hypermodified nucleosides--3 -3(3-amino-3-carboxylpropyl)uridine (acp3U) and beta-D-galactosylqueuosine (Q*). The molecule also has a pseudouridine in the middle position of the anticodon, and is the first tRNA sequenced which has an adjacent pair of N2,N2-dimethylguanosine (m22G) residues.
journal_name
Arch Biochem Biophysjournal_title
Archives of biochemistry and biophysicsauthors
Johnson GD,Pirtle IL,Pirtle RMdoi
10.1016/0003-9861(85)90647-2subject
Has Abstractpub_date
1985-01-01 00:00:00pages
448-53issue
1eissn
0003-9861issn
1096-0384pii
0003-9861(85)90647-2journal_volume
236pub_type
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