Enhancement of broodstock health and maternal immunity in gilthead seabream (Sparus aurata L.) using ExcelMOS®.

Abstract:

:The current study was conducted to investigate the effect of ExcelMOS® in enhancing the immune system of Sparus aurata broodstock and their impact on offspring health through displaying the maternal transfer of immunity. Broodstock were divided into two groups: one was injected intraperitoneally with ExcelMOS® 1 month before spawning, while the other group was used as a control (without injection). Comprehensive increase in survival rate was observed for larvae hatched from ExcelMOS®-injected broodstock than those of the control (P ≤ 0.05). Hematological analysis showed increases in leukocyte count and hematocrit percentage (P ≤ 0.05) and significant enhancement in immune assays as phagocytic, respiratory burst, lysozyme activities in ExcelMOS®-injected broodstock (P ≤ 0.05). Additionally, total immunoglobulin levels in the serum, eggs, and larvae resulted from ExcelMOS®-injected broodstock were highly significant (P ≤ 0.05) than those in the control ones. Transmission electron microscopy and semi-thin sections in posterior intestine of ExcelMOS®-injected broodstock revealed reinforcement of the epithelial barrier structure, intestinal integrity, and functionality in combination with the stimulation of innate immune system. In conclusion, immunostimulation of Sparus aurata broodstock using ExcelMOS® has improved survival of larvae and enhanced both innate and adaptive immune defense mechanisms. Further investigations are required to show the effect of ExcelMOS® on fish cultured in intensive culture systems.

journal_name

Fish Physiol Biochem

authors

AbouShabana NM,AbdelKader R,Abdel-Rahman S,Abdel-Gawad HS,Abdel-Galil AM

doi

10.1007/s10695-018-0517-x

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

1241-1251

issue

4

eissn

0920-1742

issn

1573-5168

pii

10.1007/s10695-018-0517-x

journal_volume

44

pub_type

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