Population pharmacokinetics of tacrolimus in paediatric systemic lupus erythematosus based on real-world study.

abstract：:A number of drugs have been reported to cause neuromuscular blockade and/or to increase weakness in myasthenia gravis. We report on two patients, treated with felodipine and nifedipine for arterial hypertension, who presented with an exacerbation of their myasthenia gravis and a myasthenic syndrome or exacerbation of ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Pina Latorre MA,Cobeta JC,Rodilla F,Navarro N,Zabala S

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:The aim of this review is to evaluate and summarize the available scientific information on the commonest plant extracts marketed in Western countries. In view of the intense, ongoing search for new plant extracts with powerful anti-inflammatory activity, we paid particular attention to this topic. The aim is...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Cravotto G,Boffa L,Genzini L,Garella D

更新日期：2010-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Rituximab, an anti-CD20 monoclonal antibody, is widely used with good response for the treatment of B-cell lymphoma and various refractory autoimmune diseases. Although rituximab is effective, rare but serious pulmonary adverse reactions have been reported. We report on a case of rituximab-i...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Wu Y,Jia Y,Xu J,Shuai X,Wu Y

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of 500 mg ornidazole vaginal ovules (VO) and vaginal tablets (VT) in the treatment of bacterial vaginosis. METHOD:Patients were allocated at random to one group of 50 subjects to be treated with a VO (500 mg) prepared in our laboratory and to a second group of 50 subjects to be treate...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Baloğlu E,Ozyazici M,Baloğlu A,Ova L

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the effect of diluent type, storage conditions and the nature of package on the stability of reconstituted Parecoxib sodium for injection (PSI). METHODS:Parecoxib sodium for injection is a lyophilized product for single use. It is intended for the management of acute...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Crane IM,Mulhern MG,Nema S

更新日期：2003-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Obsessive-compulsive disorder (OCD) is a chronic neuropsychiatric disorder. Selective serotonin reuptake inhibitors (SSRIs) are the first line of medication for OCD treatment; however, 40%-60% of patients with OCD do not respond to SSRIs adequately. There are growing pieces of evidence which...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Abdolhosseinzadeh S,Sina M,Ahmadiani A,Asadi S,Shams J

更新日期：2019-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:This study aimed to compare the ability of statin monotherapy (ST group), omega-3 fatty acid monotherapy (OM_A group) and combination therapy with omega-3 fatty acids and a statin (OM_S group), to reduce triglyceride (TG) levels in patients with hypertriglyceridaemia. METHODS:In this retros...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kim HS,Kim H,Jeong YJ,Yang SJ,Baik SJ,Lee H,Lee SH,Cho JH,Choi IY,Yim HW,Yoon KH

更新日期：2016-10-01 00:00:00

abstract：:A single dose pharmacokinetic study was conducted on two sustained-release formulations (75 mg) of indomethacin (Indocid capsules 'A' and Indogesic tablets 'B'). The study was carried out on 22 healthy male volunteers, who received a single oral dose (75 mg) of each product according to a randomized crossover design. ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Hasan MM,Najib NM,Muti HY

更新日期：1994-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:We report a special case of fenofibrate-induced acute severe DILI with sudden onset and rapid recovery, which is different from those in the LiverTox database. CASE SUMMARY DESCRIPTION:The acute severe DILI occurred within only 4 days after fenofibrate initial treatment for hypertriglycerid...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ma S,Liu S,Wang Q,Chen L,Yang P,Sun H

更新日期：2020-02-01 00:00:00

abstract：:Caffeine elimination was studied in 73 patients admitted to an intensive care unit, 33 of whom had liver disease. Mean plasma clearance of caffeine in patients with no liver disease (1.30 +/- 0.79 ml/kg/min) was significantly higher than in patients with liver disease (0.39 +/- 0.23 ml/kg/min). Mean half-life of caffe...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Calatayud O,Rodríguez M,Sánchez-Alcaraz A,Ibáñez P

更新日期：1995-02-01 00:00:00

abstract：:Recent reports of interactions between alcohol and benzodiazepines, tricyclic and tetracyclic antidepressants during their acute concomitant use are reviewed. Acute ingestion of alcohol (ethanol) with tranquilizers or hypnotics is responsible for several pharmacokinetic interactions that can have significant clinical ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tanaka E,Misawa S

更新日期：1998-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Bisphosphonates are the first-line medications for treating osteoporosis. The aim of our prospective study was to compare the efficacy of zoledronate with that of alendronate in women with post-menopausal osteoporosis based on the evaluations of bone mineral density (BMD) and serum levels of...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tan W,Sun J,Zhou L,Li Y,Wu X

更新日期：2016-10-01 00:00:00

abstract：:Graft patency is a major factor contributing to the long-term results of coronary artery bypass graft (CABG) surgery. The systematic overview of the Antiplatelet Trialists' Collaboration provides unequivocal evidence that antiplatelet therapy reduces by nearly one-half the odds of coronary graft occlusion following CA...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Galea J,Manché A,Goiti JJ,Locke TJ,Wilkinson GA,Smith GH

更新日期：1994-12-01 00:00:00

abstract：:The aim of the study was to determine the usage patterns of benzodiazepine hypnotics, the use of other ways of improving sleep and general sleep characteristics in patients prescribed these drugs on a regular basis and in a control group of age- and sex-matched patients not receiving hypnotics. Patients receiving regu...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Krska J,MacLeod TN

更新日期：1995-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Pregabalin is used for neuropathic and postherpetic pain and generalized anxiety. The aim of this study was to obtain the onset profiles of adverse events (AE) related to falls (AEFs) such as "somnolence," "dizziness," "loss of consciousness" and "fall" onset and several clinical factor comb...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Mukai R,Hasegawa S,Umetsu R,Nakao S,Shimada K,Uranishi H,Masuta M,Suzuki H,Nishibata Y,Nakamura M

更新日期：2019-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Moringa oleifera (MO) Lam (Moringaceae) is commonly used as food supplement and as medicine in most African countries where malaria is also endemic. Therefore, co-administration of MO with antimalarials is a possibility. This study investigated the effects of MO leaves powder on the pharmaco...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Olawoye OS,Adeagbo BA,Bolaji OO

更新日期：2018-10-01 00:00:00

abstract：:Parenterals, sterile preparations intended to be injected in man or animal, should be free from pyrogenic substances which are able to raise the thermostatic setting in the hypothalamus. This article gives an up-to-date review of the principal detection and quantification methods for these agents, with special attenti...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Vanhaecke E,Pijck J,Vuye A

更新日期：1987-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The CHOP regimen with rituximab (R-CHOP) remains the standard for chemotherapy in patients with aggressive non-Hodgkin's lymphoma (NHL). The cardiotoxicity of doxorubicin appears to be a key problem in clinical practice. We studied the cardiotoxicity of CHOP/R-CHOP regimen in a retrospective...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Limat S,Daguindau E,Cahn JY,Nerich V,Brion A,Perrin S,Woronoff-Lemsi MC,Deconinck E

更新日期：2014-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The potential beneficial therapeutic effects of cannabinoid CB₁ receptor antagonists or partial agonists have driven drug discovery and development efforts and have led to clinical candidates. It is generally assumed that these compounds are CB₁ 'selective' and produce their effects exclusiv...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Raffa RB,Ward SJ

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In September 1998, legislation was introduced in the United Kingdom to limit paracetamol pack sizes to 16 tablets of 500 mg at general sales outlets and 32 tablets of 500 mg at pharmacies. The effect of the regulations on severity of paracetamol poisoning is unclear. The aim of this study was t...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Morgan O,Hawkins L,Edwards N,Dargan P

更新日期：2007-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Chemotherapy can increase treatment-related mortality associated with future haematopoietic stem cell transplantation (HSCT) for patients with relapsed/refractory acute myeloid leukaemia (AML). There is usually insufficient time to find a suitable unrelated donor for these patients. We repor...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Zhang C,Chen XH,Liu J,Gao L,Liu Y,Gao L,Kong PY,Zhang X

更新日期：2015-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Despite recommendations to avoid fluoroquinolones (FQs) as a first-line treatment for uncomplicated cystitis, recent data suggest that FQs remain widely prescribed. Therefore, the objectives of this study were to evaluate the appropriateness of empiric FQ use compared to nitrofurantoin for u...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Robinson TF,Barsoumian AE,Aden JK,Giancola SE

更新日期：2020-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Ceftriaxone is a third-generation cephalosporin with broad-spectrum antibacterial activity. Ceftriaxone-associated urolithiasis and post-renal acute renal failure (PARF) in adults is exceedingly rare and perhaps underappreciated. We report one such case to increase appreciation of this risk ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Shen-Hua W,Fan-Yi M,Qing-Ling Z,Li-Na Z,Li-Jun M

更新日期：2016-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:The development of rapid diagnostics has revolutionized antimicrobial stewardship with efforts targeting earlier de-escalation or discontinuation of antibiotics. The respiratory viral panel (RVP) is one tool quickly able to detect common viral and bacterial pathogens using polymerase chain r...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Covert K,Bashore E,Edds M,Lewis PO

更新日期：2020-12-05 00:00:00

abstract：PURPOSE:Empirical use of intravenous (IV) itraconazole (ITZ) for febrile neutropenic patients has recently been introduced in Korea. This study was designed to investigate the population pharmacokinetics (PK) of IV-ITZ. METHODS:Sparse PK data were collected from febrile neutropenic patients undergoing empirical ITZ th...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Lee DG,Chae H,Yim DS,Park SH,Choi SM,Kim S,Choi JH,Yoo JH,Shin WS

更新日期：2009-06-01 00:00:00

abstract：:Although acetylsalicylic acid is prescribed for a broad range of diseases, it can induce a wide array of clinically recognized hypersensitivity reactions, including aspirin-intolerant asthma (AIA) with rhinitis and aspirin-intolerant urticaria (AIU) with anaphylaxis. Altered eicosanoid metabolism is the generally acce...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Palikhe NS,Kim SH,Park HS

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Antiviral medications cost-effectively reduce influenza-related morbidity and potentially mortality. We sought to assess the appropriateness of antiviral prescribing for influenza. METHOD:We performed a retrospective analysis of visits by adults to primary care clinics during influenza seasons...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Linder JA,Chan JC,Bates DW

更新日期：2006-06-01 00:00:00

abstract：:The effects of age and co-medication on steady-state phenobarbital (PB) level-dose (L/D) ratios were evaluated retrospectively in 539 paediatric patients. The PB L/D ratio increased significantly with age up to 15 years. Associated anti-epileptic therapy affected the PB L/D ratio, which was significantly increased in ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Yukawa E,Higuchi S,Aoyama T

更新日期：1992-08-01 00:00:00

abstract：:An information package was developed for general practitioners (GPs) involved in the management of home parenteral nutrition (HPN) patients. The booklet covered five major sections: background information; HPN training; complications of HPN; arrangements for a particular patient; and hospital management of HPN. This s...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Malone M

更新日期：1988-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are one of the preferred approved treatment options for people with type 2 diabetes (T2D) and inadequate glycaemic control. The objective of this review is to provide a general clinical overview of the similarities and differences in the ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Cornell S

更新日期：2020-09-01 00:00:00