Abstract：
OBJECTIVES:To confirm and extend previous results involving repetitive transcranial magnetic stimulation (rTMS) aimed at alleviating refractory central neuropathic pain (CNP). To evaluate pain relief in detail and to assess ongoing benefits after one year of treatment. DESIGN:Prospective observational study. SETTING:University hospital. Outpatient settings. PARTICIPANTS:Patients (N=80) with chronic central pain after brain or spinal cord injuries. INTERVENTIONS:High-frequency (20Hz) neuronavigated-rTMS sessions were applied on the primary motor cortex using a figure-of-eight coil positioned by a robotized arm. Patients received a minimum of 4 consecutive sessions, each separated by 3-4 weeks. MAIN OUTCOME MEASURES:Percentage of pain relief (%R), duration of pain relief (DPR), numeric rating scale (NRS), neuropathic pain symptom inventory (NPSI), and pain relief score (PRS). RESULTS:Seventy-one patients completed the study. On average, after the first 4 sessions, %R was 28% and DPR was 11 days. Fifty-four patients (76%) were responders with a permissive threshold of ≥10%R and 61% (43 patients) with a stringent threshold ≥30%R. After 12 months of treatment (15 sessions) we observed a cumulative effect on %R (48%), DPR (20d), and on the prevailing NPSI sub-score (-28%). This effect reached significance after 4 sessions and was further maintained over 12 months. Across participants, more than 1000 rTMS sessions were delivered over 6 years without any adverse effect. CONCLUSION:These results confirm that multiple rTMS sessions are both safe and have potential as a treatment for CNP. An ongoing randomized controlled trial will allow teasing out of this effect from placebo analgesia.
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Quesada C,Pommier B,Fauchon C,Bradley C,Créac'h C,Vassal F,Peyron Rdoi
10.1016/j.apmr.2018.04.013subject
Has Abstractpub_date
2018-11-01 00:00:00pages
2203-2215.e1issue
11eissn
0003-9993issn
1532-821Xpii
S0003-9993(18)30286-7journal_volume
99pub_type
杂志文章abstract：OBJECTIVES:The postural imbalance poststroke limits individuals' walking abilities as well as increase the risk of falling. We investigated the short-term treatment effects of noninvasive brain stimulation (NIBS) on functional balance and postural control in patients with stroke. DATA SOURCES:We started the search via...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,meta分析
doi：10.1016/j.apmr.2019.09.003
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:To assemble and synthesize the best evidence on the epidemiology, diagnosis, prognosis, treatment, and prevention of musculoskeletal injuries and pain in dancers. DATA SOURCES:Medline, CINAHL, PsycINFO, Embase, and other electronic databases were searched from 1966 to 2004 using key words such as dance, danc...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,评审
doi：10.1016/j.apmr.2008.02.020
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVES:To assess lumbopelvic muscle activity during different core stability exercises on and off a Swiss ball. DESIGN:Prospective comparison study. SETTING:Research laboratory. PARTICIPANTS:Eight healthy volunteers from a university population. INTERVENTION:Subjects performed 4 exercises on and off a Swiss bal...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2004.05.004
更新日期：2005-02-01 00:00:00
abstract：:The factors responsible for the increased susceptibility to decubitus ulcers of the insensitive skin of spinal cord injury (SCI) patients are not known. Autonomic dysfunction leading to defective vascularity is a possibility. SCI removes cerebral control of the isolated nervous system which may mimic denervation hyper...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(86)90073-0
更新日期：1986-03-01 00:00:00
abstract：OBJECTIVE:To examine incidence and predictors of employment stability in veterans and military service members with traumatic brain injury (TBI) who return to work. DESIGN:Prospective observational cohort study. SETTING:Four rehabilitation centers. PARTICIPANTS:Veterans and military service members (N=110) with mild...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,多中心研究
doi：10.1016/j.apmr.2017.05.012
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVE:To determine the effects of Pilates exercises on health-related quality of life (HRQOL) in individuals with juvenile idiopathic arthritis (JIA). DESIGN:Randomized, prospective, single-blind trial. SETTING:Outpatient clinic of pediatric rheumatology and the rehabilitation department. PARTICIPANTS:Children (...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2013.05.026
更新日期：2013-11-01 00:00:00
abstract：:Concerns have been raised about the capability of conventional prosthetic foot components to provide adequate support and function for activities other than walking to persons with lower limb amputations. Degenerative changes of the lumbar spine and knee joints have been linked to prolonged asymmetric loading, which m...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：OBJECTIVE:To quantify habitual walking speed and estimate the prevalence of low habitual walking speed (<0.8m/s and <0.5m/s) in nursing home residents; and secondarily to gain some insight into whether demographic, health, and functional outcomes could predict the nursing home residents' walking speed. DESIGN:Cross-se...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,多中心研究
doi：10.1016/j.apmr.2015.06.021
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:To investigate the relationship between pushrim forces and the progression of shoulder injuries in manual wheelchair users. DESIGN:Longitudinal case series. SETTING:Biomechanics laboratory and magnetic resonance imaging (MRI) facility at a Veterans Health Administration medical center and university hospita...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1053/s0003-9993(03)00282-x
更新日期：2003-11-01 00:00:00
abstract：:A 40-year-old patient with insulin-dependent (Type I) diabetes mellitus since childhood suffered a C6 spinal transection. Recurrent episodes of hypoglycemia resolved after the patient was placed on an insulin pump. The patient is able to set the insulin delivery rate and maintain the pump without assistance. Spinal co...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The purpose of this study was to analyze and compare the effects of the leg during swing and stance phases of forward propulsion of the body for both men and women. Twelve able-bodied subjects, six men and six women, were studied with a Vicon(a) gait-analysis system. A two-dimensional, sagittal-plane biomechanical ana...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：OBJECTIVE:To develop and validate a subjective measure of cognitive fatigue-the State-Trait Inventory of Cognitive Fatigue-in community-dwelling older adults. DESIGN:Scale development and test construction. SETTING:Community-dwelling older adults enrolled in a longitudinal cohort aging study. PARTICIPANTS:Participan...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2016.07.024
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:To assess the diagnostic and clinical utility of the 2-item Generalized Anxiety Disorder Scale (GAD-2) for screening anxiety symptoms in individuals with multiple sclerosis (MS). DESIGN:Cross-sectional. SETTING:University-affiliated MS neurology and rehabilitation center. PARTICIPANTS:The sample comprised ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2018.05.029
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVE:To understand the experiences of patients who had undergone neurologic rehabilitation. DESIGN:An interpretative phenomenological analysis of semistructured interviews. SETTING:Neurologic rehabilitation unit. PARTICIPANTS:A purposive convenience sample of 8 past patients. INTERVENTIONS:Not applicable. MAI...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2007.11.050
更新日期：2008-07-01 00:00:00
abstract：UNLABELLED:Pua Y-H, Cowan SM, Wrigley TV, Bennell KL. Discriminant validity of the Western Ontario and McMaster Universities Osteoarthritis Index Physical Functioning Subscale in community samples with hip osteoarthritis. OBJECTIVE:To evaluate, in a community hip osteoarthritis (OA) sample, the discriminant validity o...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2009.04.011
更新日期：2009-10-01 00:00:00
abstract：:Supine and sitting lower extremity cortical somatosensory evoked potential (CSEP) examinations were performed in 30 healthy volunteers to establish normal values and to determine variations in SEP parameters caused by positional changes, side of stimulation, and the influence of height. CSEPs were recorded at Cz'-Fz (...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：OBJECTIVE:To identify implementation priorities for poststroke aphasia management relevant to the Australian health care context. DATA SOURCES:Using systematized searches of databases (CINAHL and MEDLINE), guideline and stroke websites, and other sources, evidence was identified and extracted for 7 implementation crit...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2017.08.474
更新日期：2018-07-01 00:00:00
abstract：UNLABELLED:This self-directed learning module highlights recent developments in the acute care of stroke patients, prediction of outcome after stroke, evaluation of risk factors, secondary prevention of stroke, and the evaluation of the young adult with stroke. It is part of the study guide on stroke and neurodegenerat...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,评审
doi：10.1053/j.apmr.2003.11.013
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to determine the duration of physical activity (PA) monitoring required for reliable measurements following stroke. DESIGN:Single-center, prospective, observational study. SETTING:PA was measured in a community setting. PARTICIPANTS:Adults (N=70) poststroke. MAIN OUTCOME MEASURES...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2018.10.006
更新日期：2019-05-01 00:00:00
abstract：OBJECTIVE:To assess whether variables from a postural control test relate to and predict falls efficacy in prosthesis users. DESIGN:Twelve-month within- and between-participants repeated measures design. Participants performed the limits of stability (LOS) test protocol at study baseline and at 6-month follow-up. Part...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2018.05.016
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVE:To determine the effects of locomotor training on: (1) the International Standards for Neurological Classification of Spinal Cord Injury examination; (2) locomotion (gait speed, distance); (3) balance; and (4) functional gait speed stratifications after chronic incomplete spinal cord injury (SCI). DESIGN:Pro...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,多中心研究
doi：10.1016/j.apmr.2012.02.035
更新日期：2012-09-01 00:00:00
abstract：:This first report on the use of the Wright linear pump and its successful application in the treatment of a child with Park-Weber syndrome indicates that sequenced linear pumping is efficacious when previously tried single cell intermittent compression fails. Programmable intermittent pressure in the management of lym...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1983-03-01 00:00:00
abstract：OBJECTIVE:To compare cardiorespiratory responses between pool floor walking and overground walking (OW) in people poststroke. DESIGN:Cross-sectional study. SETTING:University-based therapeutic exercise facility. PARTICIPANTS:Participants (N=28) were comprised of 14 community-dwelling individuals poststroke (5.57±3.5...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2017.09.112
更新日期：2018-03-01 00:00:00
abstract：:The purpose of this study was to evaluate and compare resistance exercise training with and without pelvic stabilization on the development of isolated lumbar extension strength. Isometric torque of the isolated lumbar extensor muscles was measured at seven positions through a 72 degree range-of-motion on 47 men and 3...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of unilateral upper-limb strength training on the finger-pinch force control of older men. DESIGN:Pretest and post-test 6-week intervention study. SETTING:Exercise science research laboratory. PARTICIPANTS:Eleven neurologically fit older men (age range, 70-80y). INTERVENTION:The ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2007.05.014
更新日期：2007-08-01 00:00:00
abstract：:The relationship between surface myoelectric signal variables and ankle joint angle is studied in the tibialis anterior muscle of ten normal subjects during electrical stimulation of the main muscle motor point in isometric conditions. Rectangular current pulses of 0.1 ms width and 20Hz repetition rate were applied fo...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(93)90114-p
更新日期：1993-05-01 00:00:00
abstract：OBJECTIVE:To report the efficacy of injected liquid silicone (ILS) in the foot at 2 years after administration. DESIGN:Randomized controlled trial. SETTING:Diabetic foot clinic in the United Kingdom. PARTICIPANTS:Twenty-eight diabetic neuropathic patients, randomized into an active treatment group (n=14) and a place...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1053/apmr.2002.33058
更新日期：2002-07-01 00:00:00
abstract：OBJECTIVES:(1) To determine the effects of concussion-related motor impairments at different task complexities in isolation and with a cognitive dual-task and (2) to determine if self-reported balance deficits after concussion are associated with gait, quiet stance, or cognitive dual-task impairments. DESIGN:Cross-sec...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2018.07.441
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:To determine whether vestibular or cervical proprioceptive information influence the cervicocephalic relocation test to the neutral head position, by comparing head repositioning errors obtained in asymptomatic, unimpaired control subjects with those obtained in bilateral labyrinthine-defective patients and c...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2008.06.009
更新日期：2008-12-01 00:00:00
abstract：OBJECTIVE:To examine functional outcome and descriptive data of individuals with neoplastic spinal cord compression admitted to a rehabilitation unit. DESIGN:A 5-year review of consecutive patients admitted to a spinal cord injury rehabilitation unit with a diagnosis of neoplastic spinal cord compression. SETTING:A t...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(96)90276-2
更新日期：1996-09-01 00:00:00
