Abstract:
:This paper focuses on the DNA insecticides as a novel preparation against gypsy moth (Lymantria dispar) based on DNA fragments of the anti-apoptotic gene of its nuclear polyhedrosis virus. It was found that the external application of a solution with two single-stranded DNA fragments from BIR and RING domains of LdMNPV (L.dispar multicapsid nuclear polyhedrosis virus) IAP-3 (inhibitor of apoptosis) gene induces a significantly higher mortality of gypsy moth caterpillars in comparison with the application of the control solutions. This effect does not depend on the infection of caterpillars with LdMNPV. The results also show that DNA insecticides based on LdMNPV IAP-3 gene fragments can be selective in action, and at least are not harmful to tobacco hornworm (Manduca sexta) and black cutworm (Agrotis ipsilon). Part of the gypsy moth genome cloned with the fragments of BIR and RING domains of LdMNPV IAP-3 gene as primers, has an overlap with the corresponding part of the LdMNPV IAP-3 gene and L.dispar IAP-1 mRNA for an inhibitor of apoptosis protein with the high cover by query, allows assuming that we cloned a part of gypsy moth anti-apoptosis gene. This finding gives the grounding that proposed here DNA insecticides might act through the blocking of the mechanisms involved in post transcriptional expression of insect anti-apoptosis genes. The results show the insecticidal potential of the viral genome fragments that can be used to create safe and relatively fast-acting DNA insecticides to control the quantity of gypsy moth populations, important task for forestry and agriculture.
journal_name
Pestic Biochem Physioljournal_title
Pesticide biochemistry and physiologyauthors
Oberemok VV,Skorokhod OAdoi
10.1016/j.pestbp.2014.05.005subject
Has Abstractpub_date
2014-07-01 00:00:00pages
1-7eissn
0048-3575issn
1095-9939pii
S0048-3575(14)00088-1journal_volume
113pub_type
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journal_title:Pesticide biochemistry and physiology
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2014.11.010
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2017.07.009
更新日期:2017-11-01 00:00:00
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2020.104728
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pub_type: 杂志文章
doi:10.1016/j.pestbp.2012.11.007
更新日期:2013-01-01 00:00:00
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journal_title:Pesticide biochemistry and physiology
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章,评审
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更新日期:2017-11-01 00:00:00
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2020.104757
更新日期:2021-02-01 00:00:00
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章,评审
doi:10.1016/j.pestbp.2014.04.007
更新日期:2014-06-01 00:00:00
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2015.08.003
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doi:10.1016/j.pestbp.2019.07.006
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2017.01.008
更新日期:2017-10-01 00:00:00
abstract::Although insecticide resistance is a widespread problem for most insect pests, frequently the assessment of resistance occurs over a limited geographic range. Herein, we report the first widespread survey of insecticide resistance in the USA ever undertaken for the house fly, Musca domestica, a major pest in animal pr...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2013.10.006
更新日期:2013-11-01 00:00:00
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doi:10.1016/j.pestbp.2014.04.004
更新日期:2014-05-01 00:00:00
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2011.02.012
更新日期:2011-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.pestbp.2015.12.007
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journal_title:Pesticide biochemistry and physiology
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
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更新日期:2018-06-01 00:00:00
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
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