[Potential difference of the gastric mucosa in gastroduodenal disease. Relation with endoscopical and histologic findings].

Abstract:

:Most studies of gastric transmucosal potential difference concern acute damage. We studied this phenomenon in 168 patients with different pathologic processes: erosive gastritis, duodenal and prepyloric ulcer, atrophic gastritis, gastric ulcer and normal controls. Ag-AgCl electrodes and Agar-KCl bridges were used to record potential differences. Biopsies were taken from gastric antrum and body and potential differences were related to endoscopic and histologic findings. Maximal values of -29.2 + 2 and -22.2 + 1.6 for body and antrum, respectively, were found in normals. Lowest values (-19.4 + 1.4 and -14.3 + 1.5, respectively) were found in gastric ulcer, with intermediate values for the other conditions. Normal histologic findings were associated to potentials of -31 + 2 and -20 + 3.1 whereas lower values were recorded in patients with moderate or severe atrophic changes. Our findings suggest a relation between mucosal atrophy and lower transmucosal potential differences.

journal_name

Rev Med Chil

journal_title

Revista medica de Chile

authors

Defilippi C,Morales A,Smok G,Angelo S

subject

Has Abstract

pub_date

1989-04-01 00:00:00

pages

373-9

issue

4

eissn

0034-9887

issn

0717-6163

journal_volume

117

pub_type

杂志文章
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  • [Squamous cell carcinoma of the lip survival rate].

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  • [Treatment of a severe Clostridium difficile infection with colonic lavages. Report of one case].

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  • [Mitral valve repair for degenerative mitral insufficiency: likelihood of success, early and-long term results at 20 years].

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  • [Scientific ethics and frozen embryos].

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  • [Characteristics of gastric cancer in the IX region of Chile].

    abstract::The results of a prospective protocol for the management of patients with gastric cancer applied from May 1988 to June 1991 are reported. 123 patients were operated on and a resection performed in 55%. Only 14 patients had incipient tumor and 44 had "curative" surgery. There was a preponderance of non differentiated t...

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  • [Efficacy of propylthiouracil in the treatment of amiodarone-induced hyperthyroidism].

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    更新日期:1989-03-01 00:00:00

  • [Screening and barriers for treatment of postpartum depression in Chilean public primary health care centers].

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  • [Fascioliasis in populations of rural areas with high prevalence of animal infection].

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  • [Cholesterol and triglycerides in atherosclerosis: epidemiologic and physiopathologic considerations].

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    更新日期:1991-09-01 00:00:00

  • [Sexually transmitted diseases: epidemiological characteristics of cases notified in the health service of Viña del Mar-Quillota].

    abstract::During 1987 and 1988 sexually transmitted diseases affected 87.2 per 100,000 inhabitants of the Viña del Mar-Quillota area. At all ages rates were 3.8 times higher in males compared to females. Gonorrhoea, syphilis and non gonorrheal urethritis accounted for most cases. In males, 82% of cases corresponded to gonorrhoe...

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    更新日期:1991-10-01 00:00:00

  • [Cerebrovascular disease in a Neurologic Intermediate Care Unit in Chile. Analysis of 459 consecutive patients].

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  • [Default mode network and Alzheimer's disease].

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    更新日期:1995-04-01 00:00:00

  • [Impact of a diploma on medical education in a medical school in Chile].

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  • [Significance of Helicobacter pylori infection in the pathogenesis and natural history of peptic ulcer].

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