Abstract：
:The extraction and determination of phthalic acid esters (PAEs) residue in Chinese herbal preparations (CHP) by C18-functionalized magnetic nanoparticles (C18-FS-MNP) has been firstly performed. It was synthesized through coating Fe3O4 nanoparticles with sodium silicate, followed by freeze-drying technique and then modified with C18 groups. C18-FS-MNPs prepared via freeze-drying technique were superior to those particles prepared via common vacuum drying method in terms of dispersion and extraction recovery. C18-FS-MNPs demonstrated obvious enrichment effect for four model PAEs and 478-627-fold enrichment factors were obtained. The limit of detection was <1.89ng/mL and relative standard deviation was ranging from 3.7 to 5.8%. It was successfully applied for determination of trace PAEs residue in CHP with good recoveries.
journal_name
J Pharm Biomed Analjournal_title
Journal of pharmaceutical and biomedical analysisauthors
Guo B,Ji S,Zhang F,Yang B,Gu J,Liang Xdoi
10.1016/j.jpba.2014.08.027subject
Has Abstractpub_date
2014-11-01 00:00:00pages
365-368eissn
0731-7085issn
1873-264Xpii
S0731-7085(14)00411-7journal_volume
100pub_type
杂志文章abstract：:A validated analytical method for the quantitative determination of seven chemical markers occurring in a hydroalcoholic extract of Vitex agnus-castus fruits by liquid chromatography electrospray triple quadrupole tandem mass spectrometry (LC/ESI/(QqQ)MSMS) is reported. To carry out a comparative study, five commercia...
journal_title：Journal of pharmaceutical and biomedical analysis
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journal_title：Journal of pharmaceutical and biomedical analysis
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pub_type： 杂志文章
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journal_title：Journal of pharmaceutical and biomedical analysis
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journal_title：Journal of pharmaceutical and biomedical analysis
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journal_title：Journal of pharmaceutical and biomedical analysis
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journal_title：Journal of pharmaceutical and biomedical analysis
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Journal of pharmaceutical and biomedical analysis
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journal_title：Journal of pharmaceutical and biomedical analysis
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journal_title：Journal of pharmaceutical and biomedical analysis
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abstract：:The temperature dependent vibrational spectra of Genistein and Biochanin A, major components in Mongolian medicines Agi, in the range of 0.5-4.5 THz (16.7-150 cm(-1)) are presented for the first time. Over the temperature range from 295 to 77K, 12 highly resolved spectral features for the Genistein and 13 features for...
journal_title：Journal of pharmaceutical and biomedical analysis
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journal_title：Journal of pharmaceutical and biomedical analysis
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journal_title：Journal of pharmaceutical and biomedical analysis
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