当前位置： SCI文献检索 > Frontiers in Human Neuroscience期刊下所有文献 > Examining the role of the temporo-parietal network in memory, imagery, and viewpoint transformations.

Examining the role of the temporo-parietal network in memory, imagery, and viewpoint transformations.

Abstract：

:The traditional view of the medial temporal lobe (MTL) focuses on its role in episodic memory. However, some of the underlying functions of the MTL can be ascertained from its wider role in supporting spatial cognition in concert with parietal and prefrontal regions. The MTL is strongly implicated in the formation of enduring allocentric representations (e.g., O'Keefe, 1976; King et al., 2002; Ekstrom et al., 2003). According to our BBB model (Byrne et al., 2007), these representations must interact with head-centered and body-centered representations in posterior parietal cortex via a transformation circuit involving retrosplenial areas. Egocentric sensory representations in parietal areas can then cue the recall of allocentric spatial representations in long-term memory and, conversely, the products of retrieval in MTL can generate mental imagery within a parietal "window." Such imagery is necessarily egocentric and forms part of visuospatial working memory, in which it can be manipulated for the purpose of planning/imagining the future. Recent fMRI evidence (Lambrey et al., 2012; Zhang et al., 2012) supports the BBB model. To further test the model, we had participants learn the locations of objects in a virtual scene and tested their spatial memory under conditions that impose varying demands on the transformation circuit. We analyzed how brain activity correlated with accuracy in judging the direction of an object (1) from visuospatial working memory (we assume transient working memory due to the order of tasks and the absence of change in viewpoint, but long-term memory retrieval is also possible), (2) after a rotation of viewpoint, or (3) after a rotation and translation of viewpoint (judgment of relative direction). We found performance-related activity in both tasks requiring viewpoint rotation (ROT and JRD, i.e., conditions 2 and 3) in the core medial temporal to medial parietal circuit identified by the BBB model. These results are consistent with the predictions of the BBB model, and shed further light on the neural mechanisms underlying spatial memory, mental imagery and viewpoint transformations.

journal_name

Front Hum Neurosci

journal_title

Frontiers in human neuroscience

authors

Dhindsa K,Drobinin V,King J,Hall GB,Burgess N,Becker S

doi

10.3389/fnhum.2014.00709

subject

Has Abstract

pub_date

2014-09-16 00:00:00

pages

709

issn

1662-5161

journal_volume

pub_type

杂志文章

在线工具

Examining the role of the temporo-parietal network in memory, imagery, and viewpoint transformations.