The symbiont side of symbiosis: do microbes really benefit?

abstract：:Denitrification and dissimilatory nitrate reduction to ammonium (DNRA) compete for nitrate in natural and engineered environments. A known important factor in this microbial competition is the ratio of available electron donor and elector acceptor, here expressed as Ac/N ratio (acetate/nitrate-nitrogen). We studied th...

journal_title：Frontiers in microbiology

authors： van den Berg EM,Boleij M,Kuenen JG,Kleerebezem R,van Loosdrecht MC

更新日期：2016-11-24 00:00:00

abstract：:Current human immunodeficiency virus type 1 pandemic is believed to originate from cross-species transmission of simian immunodeficiency virus (SIV) into human population. Such cross-species transmission, however, is not efficient in general, because viral replication is modulated by host cell factors, with the specie...

journal_title：Frontiers in microbiology

authors： Sakuma R,Takeuchi H

更新日期：2012-04-27 00:00:00

abstract：:The lack of therapeutic options to treat infections caused by multidrug-resistant (MDR) pathogens, especially Gram-negative bacteria, is apparent. Therefore, it is imperative to develop new strategies to address the problem of antimicrobial resistance. Repurposing non-antibiotic commercial drugs for antimicrobial ther...

journal_title：Frontiers in microbiology

authors： Domalaon R,Ammeter D,Brizuela M,Gorityala BK,Zhanel GG,Schweizer F

更新日期：2019-07-10 00:00:00

abstract：:Combatting antimicrobial resistant (AMR) using a One-Health approach is essential as various bacteria, including Escherichia coli, a common bacteria, are becoming increasingly resistant and livestock may be a reservoir. The AMR gene content of 492 E. coli, isolated from 56 pig farms across Great Britain in 2014-2015, ...

journal_title：Frontiers in microbiology

authors： AbuOun M,O'Connor HM,Stubberfield EJ,Nunez-Garcia J,Sayers E,Crook DW,Smith RP,Anjum MF

更新日期：2020-05-25 00:00:00

abstract：:Omeprazole was shown to improve the anti-cancer effects of the nucleoside analogue 5-fluorouracil. Here, we combined omeprazole with the antiviral nucleoside analogues ribavirin and acyclovir. Omeprazole did not affect the antiviral effects of ribavirin in non-toxic concentrations up to 80 μg/mL but increased the acyc...

journal_title：Frontiers in microbiology

authors： Michaelis M,Kleinschmidt MC,Bojkova D,Rabenau HF,Wass MN,Cinatl J Jr

更新日期：2019-12-03 00:00:00

abstract：:Seasonal precipitation changes are increasingly severe in subtropical areas. However, the responses of soil nitrogen (N) cycle and its associated functional microorganisms to such precipitation changes remain unclear. In this study, two projected precipitation patterns were manipulated: intensifying the dry-season dro...

journal_title：Frontiers in microbiology

authors： Chen J,Nie Y,Liu W,Wang Z,Shen W

更新日期：2017-07-24 00:00:00

abstract：:In this study, we reconstructed for the first time a genome-scale metabolic model (GSMM) of Ganoderma lucidum strain CGMCC5.26, termed model iZBM1060, containing 1060 genes, 1202 metabolites, and 1404 reactions. Important findings based on model iZBM1060 and its predictions are as follows: (i) The extracellular polysa...

journal_title：Frontiers in microbiology

authors： Ma Z,Ye C,Deng W,Xu M,Wang Q,Liu G,Wang F,Liu L,Xu Z,Shi G,Ding Z

更新日期：2018-12-11 00:00:00

abstract：Background:The hepatitis E virus (HEV) represents a major cause of acute hepatitis worldwide. The majority of HEV cases occur in low-income countries, mainly Asia and Africa, where HEV causes large outbreaks associated with the consumption of contaminated water and high mortality in specific populations. In high-income...

journal_title：Frontiers in microbiology

authors： Rivero-Juarez A,Lopez-Lopez P,Frias M,Rivero A

更新日期：2019-06-26 00:00:00

abstract：:Panax ginseng rusty root rot caused by the Ilyonectria species complex is a devastating disease, and it is one of the main factors contributing to the difficulty in continual cropping. Rusty root rot occurs in all ginseng fields, but little is known about the taxonomy of the fungal pathogen complex, especially Ilyonec...

journal_title：Frontiers in microbiology

authors： Guan YM,Ma YY,Jin Q,Wang QX,Liu N,Fu YP,Zhang YY,Li Y

更新日期：2020-12-16 00:00:00

abstract：:Neisseria gonorrhoeae is the etiological factor of the sexually transmitted gonorrhea disease that may lead, under specific conditions, to systemic infections. The gonococcal genome encodes many restriction modification (RM) systems, which main biological role is to defend the pathogen from potentially harmful foreign...

journal_title：Frontiers in microbiology

authors： Kwiatek A,Mrozek A,Bacal P,Piekarowicz A,Adamczyk-Popławska M

更新日期：2015-12-21 00:00:00

abstract：:Two-component systems (TCS) are modular signal transduction pathways that allow cells to adapt to prevailing environmental conditions by modifying cellular physiology. Staphylococcus aureus has 16 TCSs to adapt to the diverse microenvironments encountered during its life cycle, including host tissues and implanted med...

journal_title：Frontiers in microbiology

authors： Burgui S,Gil C,Solano C,Lasa I,Valle J

更新日期：2018-03-07 00:00:00

abstract：:Type IV pili (T4P) are surface-exposed protein fibers that play key roles in the bacterial life cycle via surface attachment/adhesion, biofilm formation, motility, and development. The order Myxococcales (myxobacteria) are members of the class Deltaproteobacteria and known for their large genome size and complex socia...

journal_title：Frontiers in microbiology

authors： Sharma G,Burrows LL,Singer M

更新日期：2018-07-19 00:00:00

abstract：:Soil microorganisms historically have been a rich resource for natural product discovery, yet the majority of these microbes remain uncultivated and their biosynthetic capacity is left underexplored. To identify the biosynthetic potential of soil microorganisms using a culture-independent approach, we constructed a la...

journal_title：Frontiers in microbiology

authors： Santana-Pereira ALR,Sandoval-Powers M,Monsma S,Zhou J,Santos SR,Mead DA,Liles MR

更新日期：2020-12-07 00:00:00

abstract：:Bacterial cells are surrounded by an exoskeleton-like structure, the cell wall, composed primarily of the peptidoglycan (PG) sacculus. This structure is made up of glycan strands cross-linked by short peptides generating a covalent mesh that shapes bacteria and prevents their lysis due to their high internal osmotic p...

journal_title：Frontiers in microbiology

authors： Yadav AK,Espaillat A,Cava F

更新日期：2018-08-31 00:00:00

abstract：:Rhizaria are an important component of oceanic plankton communities worldwide. A number of species harbor eukaryotic microalgal symbionts, which are horizontally acquired in the environment at each generation. Although these photosymbioses are determinant for Rhizaria ability to thrive in oceanic ecosystems, the mecha...

journal_title：Frontiers in microbiology

authors： Balzano S,Corre E,Decelle J,Sierra R,Wincker P,Da Silva C,Poulain J,Pawlowski J,Not F

更新日期：2015-03-17 00:00:00

abstract：:Subseafloor sedimentary environments harbor remarkably diverse microbial communities. However, it remains unknown if the deeply buried fossils in these sediments play ecological roles in deep microbial habitats, or whether the microbial communities inhabiting such fossils differ from those in the surrounding sediment ...

journal_title：Frontiers in microbiology

authors： Hoshino T,Morono Y,Terada T,Imachi H,Ferdelman TG,Inagaki F

更新日期：2011-11-17 00:00:00

abstract：:Vitamin C is a critical dietary nutrient in human which has a wide range of regulatory effects on gene expression and physiology of Mycobacterium tuberculosis that leads to a dormant drug-tolerant phenotype. In the presence of iron, vitamin C shows a high bactericidal activity even in the drug resistant phenotype of M...

journal_title：Frontiers in microbiology

authors： Mishra A,Sarkar D

更新日期：2015-05-18 00:00:00

abstract：:Over the last years the role of fungal endophytes in plant biology has been extensively studied. A number of species were shown to positively affect plant growth and fitness, thus attempts have been made to utilize these microorganisms in agriculture and phytoremediation. Plant-fungi symbiosis requires multiple metabo...

journal_title：Frontiers in microbiology

authors： Rozpądek P,Domka AM,Nosek M,Ważny R,Jędrzejczyk RJ,Wiciarz M,Turnau K

更新日期：2018-03-19 00:00:00

abstract：:Lam proteins transport sterols between the membranes of different cellular compartments. In Saccharomyces cerevisiae, the LAM gene family consists of three pairs of paralogs. Because the function of paralogous genes can be redundant, the phenotypes of only a small number of LAM gene deletions have been reported; thus,...

journal_title：Frontiers in microbiology

authors： Sokolov SS,Vorobeva MA,Smirnova AI,Smirnova EA,Trushina NI,Galkina KV,Severin FF,Knorre DA

更新日期：2020-01-28 00:00:00

abstract：:Chlamydia muridarum, an obligate intracellular pathogen, was used to establish a murine model of female upper genital tract infection by Chlamydia trachomatis. TC0668 in C. muridarum is a hypothetical chromosomal virulence protein that is involved in upper genital tract pathogenesis. The infection of mice with the C. ...

journal_title：Frontiers in microbiology

authors： Wang Y,Arthur EW,Liu N,Li X,Xiang W,Maxwell A,Li Z,Zhou Z

更新日期：2019-11-07 00:00:00

abstract：:The use of antibiotics in food-producing animals has significantly increased animal health by lowering mortality and the incidence of diseases. Antibiotics also have largely contributed to increase productivity of farms. However, antibiotic usage in general and relevance of non-therapeutic antibiotics (growth promoter...

journal_title：Frontiers in microbiology

authors： Diarra MS,Malouin F

更新日期：2014-06-17 00:00:00

abstract：:Cyanobacteria are major contributors to global biogeochemical cycles. The genetic diversity among Cyanobacteria enables them to thrive across many habitats, although only a few studies have analyzed the association of phylogenomic clades to specific environmental niches. In this study, we adopted an ecogenomics strate...

journal_title：Frontiers in microbiology

authors： Walter JM,Coutinho FH,Dutilh BE,Swings J,Thompson FL,Thompson CC

更新日期：2017-11-14 00:00:00

abstract：:Seaweeds of the intertidal regions are a rich source of surface associated bacteria and are potential source of antimicrobial molecules. In the present study, 77 epiphytic isolates from eight different algae collected from Little Andaman were enumerated. On testing for their antimicrobial activities against certain pa...

journal_title：Frontiers in microbiology

authors： Karthick P,Mohanraju R

更新日期：2018-04-04 00:00:00

abstract：:The respiratory diseases caused by rhinovirus, respiratory syncytial virus, and influenza virus represent a large social and financial burden on healthcare worldwide. Although all three viruses have distinctly unique properties in terms of infection and replication, they share the ability to exploit/manipulate the hos...

journal_title：Frontiers in microbiology

authors： Caly L,Ghildyal R,Jans DA

更新日期：2015-08-14 00:00:00

abstract：:The abundance of methane in shale gas and of other gases such as carbon monoxide, hydrogen, and carbon dioxide as chemical process byproducts has motivated the use of gas fermentation for bioproduction. Recent advances in metabolic engineering and synthetic biology allow for engineering of microbes metabolizing a vari...

journal_title：Frontiers in microbiology

authors： Nazem-Bokaee H,Maranas CD

更新日期：2018-08-24 00:00:00

abstract：Background:Tuberculosis (TB) and non-tuberculous mycobacteriosis are serious threats to health worldwide. A simple non-sequencing method is needed for rapid diagnosis, especially in less experienced hospitals, but there is no specific biomarker commonly used for all mycobacteria. The ku gene of the prokaryotic error-pr...

journal_title：Frontiers in microbiology

authors： Zhou L,Ma C,Xiao T,Li M,Liu H,Zhao X,Wan K,Wang R

更新日期：2019-08-13 00:00:00

abstract：:High level expression of recombinant proteins in bacteria often results in their aggregation into inclusion bodies. Formation of inclusion bodies poses a major bottleneck in high-throughput recovery of recombinant protein. These aggregates have amyloid-like nature and can retain biological activity. Here, effect of ex...

journal_title：Frontiers in microbiology

authors： Singh A,Upadhyay V,Singh A,Panda AK

更新日期：2020-05-08 00:00:00

abstract：:Laccases are a family of copper-containing oxidases with important applications in bioremediation and other various industrial and biotechnological areas. There have been over two dozen reviews on laccases since 2010 covering various aspects of this group of versatile enzymes, from their occurrence, biochemical proper...

journal_title：Frontiers in microbiology

authors： Yang J,Li W,Ng TB,Deng X,Lin J,Ye X

更新日期：2017-05-16 00:00:00

abstract：:The worldwide dissemination of carbapenemase-producing Enterobacteriaceae (CPE) has become a major therapeutic concern in clinical settings. Enterobacter cloacae is a major pathogen that causes serious hospital-acquired infections. We investigated the clinical characteristics and molecular mechanisms of the first IMP-...

journal_title：Frontiers in microbiology

authors： Lee JH,Bae IK,Lee CH,Jeong S

更新日期：2017-11-28 00:00:00

abstract：:The success of Ericaceae in stressful habitats enriched in heavy metals has been ascribed to the distinctive abilities of their mycorrhizal fungal partners to withstand heavy metal stress and to enhance metal tolerance in the host plant. Whereas heavy metal tolerance has been extensively investigated in some ericoid m...

journal_title：Frontiers in microbiology

authors： Casarrubia S,Martino E,Daghino S,Kohler A,Morin E,Khouja HR,Murat C,Barry KW,Lindquist EA,Martin FM,Perotto S

更新日期：2020-03-09 00:00:00