Hepatitis E Infection in HIV-Infected Patients.

Abstract:

Background:The hepatitis E virus (HEV) represents a major cause of acute hepatitis worldwide. The majority of HEV cases occur in low-income countries, mainly Asia and Africa, where HEV causes large outbreaks associated with the consumption of contaminated water and high mortality in specific populations. In high-income countries, HEV infection is considered a zoonotic disease that is linked to the consumption of contaminated food. Although a high proportion of cases have self-limiting asymptomatic or subclinical infections, immunosuppression may modify the pathogenesis and clinical impact of this emerging disease. Results and Discussion:Here, we review the current knowledge about the epidemiology, diagnosis, clinical manifestations, management and prevention of HEV infection in HIV-infected subjects. Conclusions:Despite the increasing knowledge about the pathogenesis, epidemiology and clinical impact of HEV infection, several major factors are faced by HIV-infected patients, including treatment recommendations, immunization and risk practices.

journal_name

Front Microbiol

authors

Rivero-Juarez A,Lopez-Lopez P,Frias M,Rivero A

doi

10.3389/fmicb.2019.01425

subject

Has Abstract

pub_date

2019-06-26 00:00:00

pages

1425

issn

1664-302X

journal_volume

10

pub_type

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