当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY期刊下所有文献 > Granulomatosis with polyangiitis presenting as facial nerve palsy in a teenager.

Granulomatosis with polyangiitis presenting as facial nerve palsy in a teenager.

Abstract：

:Granulomatosis with polyangiitis (GPA, previously known as Wegener's granulomatosis) is an autoimmune systemic small-vessel vasculitis, associated with the presence of anti-neurophil cytoplasmic antibodies with a cytoplasmic staining pattern (c-ANCA). It is characterized by necrotizing granulomas, usually affecting the airways and kidneys. GPA should be considered when patients do not improve despite adequate treatment of otologic symptoms, when patients have unspecific symptoms suggesting systemic disease (e.g. fever, malaise), or when other organs are involved (kidney, lungs, etc.). We present an interesting case of a 14-year-old female with eight-weeks of bilateral otalgia, unilateral facial nerve palsy, decreased appetite, and fatigue refractory to steroid, anti-viral, and antibiotic treatment ultimately diagnosed with GPA.

journal_name

Int J Pediatr Otorhinolaryngol

journal_title

International journal of pediatric otorhinolaryngology

authors

Wang JC,Leader BA,Crane RA,Koch BL,Smith MM,Ishman SL

doi

10.1016/j.ijporl.2018.02.009

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

160-163

eissn

0165-5876

issn

1872-8464

pii

S0165-5876(18)30075-2

journal_volume

107

pub_type

杂志文章

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