当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY期刊下所有文献 > The effectiveness of nasal saline irrigation (seawater) in treatment of allergic rhinitis in children.

The effectiveness of nasal saline irrigation (seawater) in treatment of allergic rhinitis in children.

Abstract：

OBJECTIVE:To evaluate the effect of nasal saline irrigation in the treatment of allergic rhinitis (AR) in children and to assess whether nasal saline irrigation could be used as a complementary therapy for AR in children in combination with the intranasal corticosteroids (INS). METHOD:In total, 61 children with AR were divided into three groups: the nasal irrigation, intranasal corticosteroid, and combined treatment groups. Symptoms and signs of AR and eosinophils (EOS) in the nasal secretions were evaluated after 4 weeks, 8 weeks, and 12 weeks of treatment. RESULTS:In AR children treated with nasal irrigation and a decreased the INS dose, a significant improvement in symptoms and signs and a significant decrease in the mean EOS count in nasal secretions were observed at week 12. CONCLUSION:Nasal saline irrigation with physiological seawater is well tolerated and benefits the patients with AR, and can thus be considered a good adjunctive treatment option to maintain the effectiveness of the INS at a lower dose, thus resulting in reduced side effects and a decreased economic burden.

journal_name

Int J Pediatr Otorhinolaryngol

journal_title

International journal of pediatric otorhinolaryngology

authors

Chen JR,Jin L,Li XY

doi

10.1016/j.ijporl.2014.04.026

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

1115-8

issue

7

eissn

0165-5876

issn

1872-8464

pii

S0165-5876(14)00238-9

journal_volume

78

pub_type

杂志文章,随机对照试验

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