Abstract:
INTRODUCTION:The ever-increasing developments in pharmaceutical formulations have led to the widespread use of biodegradable polymers in various forms and configurations. In particular, interpenetrating network (IPN) and semi-IPN polymer structures that are capable of releasing drugs in a controlled manner have gained much wider importance in recent years. AREAS COVERED:Recently, IPNs and semi-IPNs have emerged as innovative materials of choice in controlled release (CR) of drugs as the release from these systems depends on pH of the media and temperature in addition to the nature of the system. These networks can be prepared as smart hydrogels following chemical or physical crosslinking methods to show remarkable drug release patterns compared to single polymer systems. EXPERT OPINION:A large number of IPNs and semi-IPNs have been reported in the literature. The present review is focused on the preparation methods and their CR properties with reference to anticancer, anti-asthmatic, antibiotic, anti-inflammatory, anti-tuberculosis and antihypertensive drugs, as majority of these drugs have been reported to be the ideal choices for using IPNs and semi-IPNs.
journal_name
Expert Opin Drug Delivjournal_title
Expert opinion on drug deliveryauthors
Aminabhavi TM,Nadagouda MN,More UA,Joshi SD,Kulkarni VH,Noolvi MN,Kulkarni PVdoi
10.1517/17425247.2014.974871subject
Has Abstractpub_date
2015-04-01 00:00:00pages
669-88issue
4eissn
1742-5247issn
1744-7593journal_volume
12pub_type
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journal_title:Expert opinion on drug delivery
pub_type: 杂志文章,评审
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journal_title:Expert opinion on drug delivery
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journal_title:Expert opinion on drug delivery
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journal_title:Expert opinion on drug delivery
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journal_title:Expert opinion on drug delivery
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journal_title:Expert opinion on drug delivery
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journal_title:Expert opinion on drug delivery
pub_type: 杂志文章,评审
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journal_title:Expert opinion on drug delivery
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pub_type: 社论
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